*************Generated from HitPredict database (11Aug2025)*************
List of interactions for P30189|TOP1|Drosophila melanogaster|Interactions:37
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Interactor A ID	Interactor B ID	Interactor A Name	Interactor B Name	Interactor A Alias	Interactor B Alias	Interaction detection methods	First author	Publications	Interactor A Taxonomy	Interactor B Taxonomy	Interaction type	Source database	Interaction identifier	Confidence score
uniprotkb:P30189	uniprotkb:Q9W124	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9W124_DROME(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:22036573|pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.54|interaction-score:0.571
uniprotkb:P30189	uniprotkb:Q9V8P9	uniprotkb:TOP1_DROME(gene name)	uniprotkb:TOPRS_DROME(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down)	-	pubmed:14871887	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-2295664	annotation-score:0.60|method-score:0.52|interaction-score:0.561
uniprotkb:P30189	uniprotkb:Q9VDE5	uniprotkb:TOP1_DROME(gene name)	uniprotkb:PPAN_DROME(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:22036573|pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.54|interaction-score:0.547
uniprotkb:P30189	uniprotkb:Q9I7K8	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9I7K8_DROME(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38270169	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-52312724	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P30189	uniprotkb:Q9VGU4	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VGU4_DROME(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38270169	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-52313553	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P30189	uniprotkb:Q9W379	uniprotkb:TOP1_DROME(gene name)	uniprotkb:ZPR1_DROME(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:14605208	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-279935	annotation-score:0.55|method-score:0.43|interaction-score:0.486
uniprotkb:P30189	uniprotkb:P46150	uniprotkb:TOP1_DROME(gene name)	uniprotkb:MOEH_DROME(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:15710747	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:445013	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P30189	uniprotkb:Q04652	uniprotkb:TOP1_DROME(gene name)	uniprotkb:KELC_DROME(gene name)	-	-	psi-mi:MI:1313(proximity labelling technology)	-	pubmed:31208963	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2869833	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P30189	uniprotkb:A1Z909	uniprotkb:TOP1_DROME(gene name)	uniprotkb:A1Z909_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q6NQY9	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q6NQY9_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q7JQN4	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q7JQN4_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q8SY39	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q8SY39_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VD28	uniprotkb:TOP1_DROME(gene name)	uniprotkb:JMJD6_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VFH2	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VFH2_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VJG2	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VJG2_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VJZ7	uniprotkb:TOP1_DROME(gene name)	uniprotkb:RRP1L_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VRI0	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VRI0_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56890428	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VYQ9	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VYQ9_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VZ88	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VZ88_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9VZF5	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VZF5_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:Q9W3C2	uniprotkb:TOP1_DROME(gene name)	uniprotkb:NOP53_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P30189	uniprotkb:O96651	uniprotkb:TOP1_DROME(gene name)	uniprotkb:TOP3B_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q7K2B0	uniprotkb:TOP1_DROME(gene name)	uniprotkb:RRP8_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q7KVQ0	uniprotkb:TOP1_DROME(gene name)	uniprotkb:GAR1_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q94513	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q94513_DROME(gene name)	-	-	psi-mi:MI:0006(anti bait coimmunoprecipitation)	-	pubmed:36029240	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-38257722	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9V426	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9V426_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9VBX1	uniprotkb:TOP1_DROME(gene name)	uniprotkb:NEMF_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9VC93	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VC93_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9VGZ2	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VGZ2_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9VHM3	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VHM3_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9W3Y0	uniprotkb:TOP1_DROME(gene name)	uniprotkb:ZN593_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P30189	uniprotkb:Q9W0R0	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9W0R0_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P30189	uniprotkb:Q9W108	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9W108_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P30189	uniprotkb:P91926	uniprotkb:TOP1_DROME(gene name)	uniprotkb:AP2A_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.16|method-score:0.33|interaction-score:0.232
uniprotkb:P30189	uniprotkb:Q7K0L8	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q7K0L8_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.16|method-score:0.33|interaction-score:0.232
uniprotkb:P30189	uniprotkb:Q9VT38	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9VT38_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56922741	annotation-score:0.16|method-score:0.33|interaction-score:0.232
uniprotkb:P30189	uniprotkb:Q9W4K1	uniprotkb:TOP1_DROME(gene name)	uniprotkb:Q9W4K1_DROME(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:38944040	taxid:7227(Drosophila melanogaster)	taxid:7227(Drosophila melanogaster)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-56894209	annotation-score:0.16|method-score:0.33|interaction-score:0.232
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