*************Generated from HitPredict database (15Jul2024)*************
List of interactions for P06700|SIR2|Saccharomyces cerevisiae S288C|Interactions:103
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Interactor A ID	Interactor B ID	Interactor A Name	Interactor B Name	Interactor A Alias	Interactor B Alias	Interaction detection methods	First author	Publications	Interactor A Taxonomy	Interactor B Taxonomy	Interaction type	Source database	Interaction identifier	Confidence score
uniprotkb:P06700	uniprotkb:P11978	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SIR4_YEAST(gene name)	-	-	psi-mi:MI:0045(experimental interaction detection)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0096(pull down)|psi-mi:MI:0401(biochemical)|psi-mi:MI:0114(x-ray crystallography)	-	pubmed:9000052|pubmed:9122169|pubmed:11805837|pubmed:11805826|pubmed:8752220|pubmed:12024030|pubmed:11500379|pubmed:15282295|pubmed:26319015|pubmed:16956377|pubmed:19217406|pubmed:19782027|pubmed:21822217|pubmed:21896656|pubmed:22654676|pubmed:23299941|pubmed:10219245|pubmed:10757754|pubmed:10835361|pubmed:16554755|pubmed:16543151|pubmed:17043313|pubmed:17316680|pubmed:17676954|pubmed:37968396|pubmed:21664583|pubmed:21690292|pubmed:23307867|pubmed:21179020|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:2271162	annotation-score:1.00|method-score:0.99|interaction-score:0.993
uniprotkb:P06700	uniprotkb:P06700	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SIR2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0114(x-ray crystallography)|psi-mi:MI:0096(pull down)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:9122169|pubmed:27185881|pubmed:16543151|pubmed:17043313|pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-2887777	annotation-score:1.00|method-score:0.81|interaction-score:0.902
uniprotkb:P06700	uniprotkb:P47035	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NET1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0096(pull down)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0401(biochemical)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:10219244|pubmed:11511359|pubmed:11805826|pubmed:11960554|pubmed:12923057|pubmed:11500379|pubmed:10219245|pubmed:10835361|pubmed:15282295|pubmed:26951198|pubmed:17043313|pubmed:30802237|pubmed:37968396|pubmed:20489023|pubmed:26319015|pubmed:16554755|pubmed:17316680|pubmed:20947565|pubmed:21179020|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.60|method-score:0.98|interaction-score:0.766
uniprotkb:P06700	uniprotkb:P06701	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SIR3_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down)|psi-mi:MI:0401(biochemical)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:10219245|pubmed:15282295|pubmed:16543151|pubmed:17043313|pubmed:9122169|pubmed:15907466|pubmed:15899856|pubmed:18794362	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-443615	annotation-score:0.60|method-score:0.93|interaction-score:0.749
uniprotkb:P06700	uniprotkb:Q00684	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:CDC14_YEAST(gene name)	-	-	psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:10219244|pubmed:15282295|pubmed:17043313|pubmed:37968396|pubmed:29738528|pubmed:20489023|pubmed:21127052|pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-443603	annotation-score:0.60|method-score:0.92|interaction-score:0.745
uniprotkb:P06700	uniprotkb:P02309	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H4_YEAST(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0415(enzymatic study)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:30455303|pubmed:10693811|pubmed:17889663|pubmed:19217406|pubmed:22654676|pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2887777	annotation-score:0.60|method-score:0.88|interaction-score:0.726
uniprotkb:P06700	uniprotkb:P61830	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H3_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0415(enzymatic study)|psi-mi:MI:0686(unspecified method)	-	pubmed:19782027|pubmed:10693811|pubmed:17889663|pubmed:19217406|pubmed:22474337	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:644619	annotation-score:0.60|method-score:0.84|interaction-score:0.708
uniprotkb:P06700	uniprotkb:O13329	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:FOB1_YEAST(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:26063576|pubmed:12923057|pubmed:26951198|pubmed:20179323|pubmed:22362748|pubmed:17043313|pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2887777	annotation-score:0.55|method-score:0.91|interaction-score:0.706
uniprotkb:P06700	uniprotkb:Q02208	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:TOF2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:17043313|pubmed:37968396|pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.60|method-score:0.74|interaction-score:0.667
uniprotkb:P06700	uniprotkb:P00359	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:G3P3_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:11805826|pubmed:24146631|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.60|method-score:0.74|interaction-score:0.665
uniprotkb:P06700	uniprotkb:P32354	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MCM10_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:16328881|pubmed:19064704|pubmed:16085704	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-1565438	annotation-score:0.55|method-score:0.74|interaction-score:0.636
uniprotkb:P06700	uniprotkb:P02293	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H2B1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:17043313|pubmed:19217406|pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2884858	annotation-score:0.60|method-score:0.67|interaction-score:0.633
uniprotkb:P06700	uniprotkb:Q06340	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ESC2_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:12399377|pubmed:25631822|pubmed:18757937	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:320435	annotation-score:0.55|method-score:0.69|interaction-score:0.617
uniprotkb:P06700	uniprotkb:P19454	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:CSK22_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:26329457|pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:7713125	annotation-score:0.60|method-score:0.62|interaction-score:0.611
uniprotkb:P06700	uniprotkb:P02829	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP82_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0397(two hybrid array)	-	pubmed:15879519|pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-864078	annotation-score:0.60|method-score:0.62|interaction-score:0.608
uniprotkb:P06700	uniprotkb:Q08119	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ESC8_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:12399377|pubmed:27185881	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:1535097	annotation-score:0.55|method-score:0.64|interaction-score:0.593
uniprotkb:P06700	uniprotkb:P10964	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPA1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:12923057|pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3610764	annotation-score:0.60|method-score:0.57|interaction-score:0.584
uniprotkb:P06700	uniprotkb:P22138	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPA2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:12923057|pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3612197	annotation-score:0.60|method-score:0.57|interaction-score:0.584
uniprotkb:P06700	uniprotkb:Q12457	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NSI1_YEAST(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:22362748	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:635409	annotation-score:0.60|method-score:0.52|interaction-score:0.561
uniprotkb:P06700	uniprotkb:P24279	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MCM3_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:19064704	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:351376	annotation-score:0.60|method-score:0.51|interaction-score:0.552
uniprotkb:P06700	uniprotkb:P10592	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP72_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.60|method-score:0.51|interaction-score:0.552
uniprotkb:P06700	uniprotkb:P11484	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SSB1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.60|method-score:0.51|interaction-score:0.552
uniprotkb:P06700	uniprotkb:P32589	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP7F_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.60|method-score:0.51|interaction-score:0.552
uniprotkb:P06700	uniprotkb:Q12192	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RFM1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:17043313|pubmed:21690292	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-2212712	annotation-score:0.50|method-score:0.60|interaction-score:0.549
uniprotkb:P06700	uniprotkb:P53165	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SGF73_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down)	-	pubmed:25043177	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2396666	annotation-score:0.55|method-score:0.52|interaction-score:0.537
uniprotkb:P06700	uniprotkb:P16521	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:EF3A_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:11805826|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.50|method-score:0.58|interaction-score:0.537
uniprotkb:P06700	uniprotkb:P07248	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ADR1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P06700	uniprotkb:P15790	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:CSK21_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:7713125	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P06700	uniprotkb:P38147	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:CHK1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:7713125	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P06700	uniprotkb:P53233	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:FMP48_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:7556670	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P06700	uniprotkb:Q04660	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ERB1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:P06700	uniprotkb:P22146	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:GAS1_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down)	-	pubmed:19541632	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-15789981	annotation-score:0.55|method-score:0.51|interaction-score:0.529
uniprotkb:P06700	uniprotkb:P04051	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPC1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16554755	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0471(mint)	mint:2271040	annotation-score:0.60|method-score:0.44|interaction-score:0.515
uniprotkb:P06700	uniprotkb:P28000	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPAC2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16554755	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0471(mint)	mint:2271076	annotation-score:0.60|method-score:0.44|interaction-score:0.515
uniprotkb:P06700	uniprotkb:Q06142	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:IMB1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:17043313	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-2212712	annotation-score:0.60|method-score:0.44|interaction-score:0.515
uniprotkb:P06700	uniprotkb:P00572	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:KTHY_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:7713125	annotation-score:0.55|method-score:0.48|interaction-score:0.513
uniprotkb:P06700	uniprotkb:P29539	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RIF1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.55|method-score:0.48|interaction-score:0.513
uniprotkb:P06700	uniprotkb:Q03785	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:VHS1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.55|method-score:0.48|interaction-score:0.513
uniprotkb:P06700	uniprotkb:P54786	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ZDS2_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:10398844	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:143201	annotation-score:0.60|method-score:0.43|interaction-score:0.508
uniprotkb:P06700	uniprotkb:P32828	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SLX5_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down)	-	pubmed:18086879	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:268437	annotation-score:0.55|method-score:0.46|interaction-score:0.504
uniprotkb:P06700	uniprotkb:P39520	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:IFH1_YEAST(gene name)	-	-	psi-mi:MI:0415(enzymatic study)	-	pubmed:23973296	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:887082	annotation-score:0.60|method-score:0.42|interaction-score:0.501
uniprotkb:P06700	uniprotkb:P21691	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SIR1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:17043313	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-2212712	annotation-score:0.55|method-score:0.44|interaction-score:0.493
uniprotkb:P06700	uniprotkb:P22139	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPAB5_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16554755	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0471(mint)	mint:2271110	annotation-score:0.55|method-score:0.44|interaction-score:0.493
uniprotkb:P06700	uniprotkb:P38990	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SAK1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.50|method-score:0.48|interaction-score:0.489
uniprotkb:P06700	uniprotkb:P54861	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:DNM1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.50|method-score:0.48|interaction-score:0.489
uniprotkb:P06700	uniprotkb:P29496	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MCM5_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:19064704	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:351372	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P06700	uniprotkb:P32829	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MRE11_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:25631822	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2384580	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P06700	uniprotkb:P38132	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MCM7_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:19064704	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:351374	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P06700	uniprotkb:P50111	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ZDS1_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:10398844	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:143197	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P06700	uniprotkb:P53091	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MCM6_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)	-	pubmed:19064704	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:351373	annotation-score:0.60|method-score:0.39|interaction-score:0.481
uniprotkb:P06700	uniprotkb:P02294	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H2B2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:17043313	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:238030	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P04786	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:TOP1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:27825925	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:1536715	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P04911	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H2A1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:19217406	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:346483	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P07703	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPAC1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3611758	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P22216	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RAD53_YEAST(gene name)	-	-	psi-mi:MI:1313(proximity labelling technology)	-	pubmed:37766847	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3574850	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P25364	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HCM1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:20847055	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:479687	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P30822	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:XPO1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:36585257	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3539489	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P32505	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NAB2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:33137177	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2907335	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P32529	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPA12_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3612282	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P32583	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SRP40_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3614241	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P32642	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:GLRX4_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:27085841	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2393960	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P34241	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:URB1_YEAST(gene name)	-	-	psi-mi:MI:1313(proximity labelling technology)	-	pubmed:36018804	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3540746	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P35208	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SPT10_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:25228766	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:1027934	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P38074	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HMT1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:22997150	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:736511	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P46676	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SUM1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:17676954	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:239652	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P53940	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:APJ1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:32492414	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3018079	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q01080	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RPA49_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3610791	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q02336	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ADA2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:19737915	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:349660	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q02821	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:IMA1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:17043313	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-2212712	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q03835	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:GLRX3_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:27085841	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2393961	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q12196	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RIO1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37263996	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3547001	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:Q12749	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SMC6_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:33979898	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3021903	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P06700	uniprotkb:P47123	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:MOG1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:30249596	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2535102	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P06700	uniprotkb:Q06148	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NEJ1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:34244791	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3389012	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P06700	uniprotkb:Q08490	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SGO1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:33929514	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3563554	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P06700	uniprotkb:P53919	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NAF1_YEAST(gene name)	-	-	psi-mi:MI:0397(two hybrid array)	-	pubmed:14690591	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-859036	annotation-score:0.60|method-score:0.35|interaction-score:0.457
uniprotkb:P06700	uniprotkb:P04912	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:H2A2_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2887777	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P07259	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:PYR1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P10591	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP71_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-3677146	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P32590	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP79_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-3684543	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P36124	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SET3_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2887220	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P39101	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:CAJ1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-3654138	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P40150	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:SSB2_YEAST(gene name)	-	-	psi-mi:MI:0401(biochemical)	-	pubmed:23332755	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0463(biogrid)	biogrid:1062269	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:Q12495	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RLF2_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2882508	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P06700	uniprotkb:P14126	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RL3_YEAST(gene name)	-	-	psi-mi:MI:1313(proximity labelling technology)	-	pubmed:36018804	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3540716	annotation-score:0.50|method-score:0.38|interaction-score:0.437
uniprotkb:P06700	uniprotkb:P38182	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ATG8_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:36585257	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3539488	annotation-score:0.50|method-score:0.38|interaction-score:0.437
uniprotkb:P06700	uniprotkb:P39960	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:BEM2_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3609405	annotation-score:0.50|method-score:0.38|interaction-score:0.437
uniprotkb:P06700	uniprotkb:Q04947	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RTN1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:17043313	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:238034	annotation-score:0.50|method-score:0.38|interaction-score:0.437
uniprotkb:P06700	uniprotkb:P32447	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ASF1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2881951	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P06700	uniprotkb:Q99337	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:YN12B_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2887777	annotation-score:0.55|method-score:0.33|interaction-score:0.426
uniprotkb:P06700	uniprotkb:P02994	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:EF1A_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P05317	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RLA0_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P32324	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:EF2_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P32905	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:RSSA1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P33416	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:HSP78_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-3747203	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P46675	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:STU2_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:21179020	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-2888241	annotation-score:0.50|method-score:0.33|interaction-score:0.407
uniprotkb:P06700	uniprotkb:P00330	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:ADH1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:11805826|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.16|method-score:0.58|interaction-score:0.307
uniprotkb:P06700	uniprotkb:P15703	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:BGL2_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:11805826|pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.16|method-score:0.58|interaction-score:0.307
uniprotkb:P06700	uniprotkb:P36103	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:YKC3_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:20489023	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0471(mint)	mint:4653931	annotation-score:0.16|method-score:0.48|interaction-score:0.279
uniprotkb:P06700	uniprotkb:P10963	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:PCKA_YEAST(gene name)	-	-	psi-mi:MI:0415(enzymatic study)	-	pubmed:19303850	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:336253	annotation-score:0.16|method-score:0.42|interaction-score:0.261
uniprotkb:P06700	uniprotkb:Q06389	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:NCS1_YEAST(gene name)	-	-	psi-mi:MI:0397(two hybrid array)	-	pubmed:14690591	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-854659	annotation-score:0.16|method-score:0.35|interaction-score:0.238
uniprotkb:P06700	uniprotkb:P00549	uniprotkb:SIR2_YEAST(gene name)	uniprotkb:KPYK1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-784758	annotation-score:0.16|method-score:0.33|interaction-score:0.232
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