*************Generated from HitPredict database (15Jul2024)*************
List of interactions for Q6S5L8|SHC4|Homo sapiens|Interactions:21
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Interactor A ID	Interactor B ID	Interactor A Name	Interactor B Name	Interactor A Alias	Interactor B Alias	Interaction detection methods	First author	Publications	Interactor A Taxonomy	Interactor B Taxonomy	Interaction type	Source database	Interaction identifier	Confidence score
uniprotkb:Q6S5L8	uniprotkb:P00533	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:EGFR_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0112(ubiquitin reconstruction)|psi-mi:MI:0729(luminescence based mammalian interactome mapping)	-	pubmed:24430869|pubmed:25402006|pubmed:24658140|pubmed:28724758|pubmed:22973453|pubmed:unassigned2173	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-9690020	annotation-score:1.00|method-score:0.91|interaction-score:0.952
uniprotkb:Q6S5L8	uniprotkb:Q92529	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:SHC3_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:28514442|pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54652316	annotation-score:1.00|method-score:0.62|interaction-score:0.789
uniprotkb:Q6S5L8	uniprotkb:P62993	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:GRB2_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:24430869|pubmed:28213521	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2561485	annotation-score:1.00|method-score:0.57|interaction-score:0.754
uniprotkb:Q6S5L8	uniprotkb:P08581	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:MET_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0053(fluorescence polarization spectroscopy)	-	pubmed:24728074	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-9475578	annotation-score:1.00|method-score:0.48|interaction-score:0.692
uniprotkb:Q6S5L8	uniprotkb:P10721	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:KIT_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0053(fluorescence polarization spectroscopy)	-	pubmed:24728074	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-9466760	annotation-score:1.00|method-score:0.48|interaction-score:0.692
uniprotkb:Q6S5L8	uniprotkb:Q02763	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:TIE2_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0415(enzymatic study)	-	pubmed:33495401	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:3201134	annotation-score:1.00|method-score:0.48|interaction-score:0.692
uniprotkb:Q6S5L8	uniprotkb:P04626	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:ERBB2_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)	-	pubmed:22973453	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2846972	annotation-score:1.00|method-score:0.42|interaction-score:0.647
uniprotkb:Q6S5L8	uniprotkb:P21860	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:ERBB3_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)	-	pubmed:22973453	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2847034	annotation-score:1.00|method-score:0.42|interaction-score:0.647
uniprotkb:Q6S5L8	uniprotkb:Q15303	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:ERBB4_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)	-	pubmed:22973453	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2847097	annotation-score:1.00|method-score:0.42|interaction-score:0.647
uniprotkb:Q6S5L8	uniprotkb:P04629	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:NTRK1_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:28213521	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2561484	annotation-score:1.00|method-score:0.38|interaction-score:0.618
uniprotkb:Q6S5L8	uniprotkb:Q06124	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:PTN11_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:28213521	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2561487	annotation-score:1.00|method-score:0.38|interaction-score:0.618
uniprotkb:Q6S5L8	uniprotkb:Q16620	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:NTRK2_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:28213521	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2529636	annotation-score:1.00|method-score:0.38|interaction-score:0.618
uniprotkb:Q6S5L8	uniprotkb:Q8NFP9	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:NBEA_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:28514442|pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54652316	annotation-score:0.60|method-score:0.62|interaction-score:0.611
uniprotkb:Q6S5L8	uniprotkb:Q9H706	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:GARE1_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:28514442|pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54652316	annotation-score:0.60|method-score:0.62|interaction-score:0.611
uniprotkb:Q6S5L8	uniprotkb:O15111	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:IKKA_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:28514442|pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54652316	annotation-score:0.50|method-score:0.62|interaction-score:0.558
uniprotkb:Q6S5L8	uniprotkb:P17707	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:DCAM_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:28514442|pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54652316	annotation-score:0.50|method-score:0.62|interaction-score:0.558
uniprotkb:Q6S5L8	uniprotkb:P10275	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:ANDR_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0053(fluorescence polarization spectroscopy)	-	pubmed:24728074	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0469(intact)	intact:EBI-9455041	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:Q6S5L8	uniprotkb:Q9H093	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:NUAK2_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:33961781	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-54644142	annotation-score:0.60|method-score:0.48|interaction-score:0.536
uniprotkb:Q6S5L8	uniprotkb:P07949	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:RET_HUMAN(gene name)	-	-	psi-mi:MI:0686(unspecified method)	-	pubmed:28213521	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2561483	annotation-score:1.00|method-score:0.28|interaction-score:0.527
uniprotkb:Q6S5L8	uniprotkb:P22681	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:CBL_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:28724758	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2485593	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:Q6S5L8	uniprotkb:Q15025	uniprotkb:SHC4_HUMAN(gene name)	uniprotkb:TNIP1_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:36574265	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3652639	annotation-score:0.50|method-score:0.38|interaction-score:0.437
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