*************Generated from HitPredict database (15Jul2024)************* List of interactions for P36004|KKQ8|Saccharomyces cerevisiae S288C|Interactions:46 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:P36004 uniprotkb:P22204 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:DBF2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894|pubmed:16242037 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:204967 annotation-score:1.00|method-score:0.60|interaction-score:0.778 uniprotkb:P36004 uniprotkb:P29311 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:BMH1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0007(anti tag coimmunoprecipitation) - pubmed:37968396|pubmed:18719252|pubmed:20489023 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0471(mint) mint:7713125 annotation-score:0.60|method-score:0.74|interaction-score:0.664 uniprotkb:P36004 uniprotkb:P00546 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:CDK1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:463695 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P21965 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:MCK1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:199157 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P23292 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:KC12_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:201445 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P31374 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PSK1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:198343 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P32361 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:IRE1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:198653 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P32581 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:IME2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:198552 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P35182 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PP2C1_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520969 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P38623 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:RCK2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:200228 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P38691 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:KSP1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:198890 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P47116 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PTK2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:199967 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:Q01389 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:BCK1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:197997 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:Q12310 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PRR2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:199733 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:P36004 uniprotkb:P34730 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:BMH2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:18719252|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-2344220 annotation-score:0.60|method-score:0.60|interaction-score:0.600 uniprotkb:P36004 uniprotkb:P21734 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:UBC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation) - pubmed:20489023 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0471(mint) mint:7556670 annotation-score:0.60|method-score:0.48|interaction-score:0.536 uniprotkb:P36004 uniprotkb:P04650 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:RL39_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520972 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P10081 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:IF4A_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520975 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P32288 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:GLNA_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520968 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P32458 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:CDC11_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520965 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P37254 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:ADCS_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520963 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P40210 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:SIP5_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520974 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P40825 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:SYA_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520964 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P43123 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:UAP1_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520970 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P43573 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:BUD27_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520967 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:Q04336 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:YM54_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520979 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:P36004 uniprotkb:P36068 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:SHE2_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520973 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:P36004 uniprotkb:P38870 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:YHY2_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520977 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:P36004 uniprotkb:P42938 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:TDA10_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520976 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:P36004 uniprotkb:P49723 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:RIR4_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520971 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:P36004 uniprotkb:P04801 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:SYTC_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3610929 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P36004 uniprotkb:P0CS90 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:HSP77_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:25792736 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1534581 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P36004 uniprotkb:P38187 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:UBP13_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:22902402 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:931954 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P36004 uniprotkb:P47069 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:MPS3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:30417519 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2543539 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P36004 uniprotkb:P33324 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:YKJ1_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520978 annotation-score:0.50|method-score:0.42|interaction-score:0.457 uniprotkb:P36004 uniprotkb:P07259 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PYR1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-784865 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P36004 uniprotkb:P10591 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:HSP71_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3671964 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P36004 uniprotkb:P39076 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:TCPB_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3823329 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P36004 uniprotkb:P40433 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:6P21_YEAST(gene name) - - psi-mi:MI:0007(anti tag coimmunoprecipitation) - pubmed:17559233 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0471(mint) mint:6489723 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P36004 uniprotkb:P29055 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:TF2B_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37863410 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3640590 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:P36004 uniprotkb:P38931 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:SSN2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:33678121 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3403645 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:P36004 uniprotkb:P43583 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:BLM10_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-784865 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P36004 uniprotkb:P46988 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:PFD1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3737883 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P36004 uniprotkb:P40355 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:YJ31_YEAST(gene name) - - psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11805837 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-16289899 annotation-score:0.16|method-score:0.48|interaction-score:0.279 uniprotkb:P36004 uniprotkb:Q03981 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:CSN9_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:21460040 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:520966 annotation-score:0.16|method-score:0.42|interaction-score:0.261 uniprotkb:P36004 uniprotkb:P53120 uniprotkb:KKQ8_YEAST(gene name) uniprotkb:YGO0_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3610928 annotation-score:0.16|method-score:0.38|interaction-score:0.249 *************Service provided by Combinatics****************************