*************Generated from HitPredict database (15Jul2024)************* List of interactions for Q08967|FLC1|Saccharomyces cerevisiae S288C|Interactions:42 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:Q08967 uniprotkb:Q03640 uniprotkb:FLC1_YEAST(gene name) uniprotkb:TCB3_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557|pubmed:22615397 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.60|method-score:0.63|interaction-score:0.613 uniprotkb:Q08967 uniprotkb:P53049 uniprotkb:FLC1_YEAST(gene name) uniprotkb:YOR1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.55|method-score:0.63|interaction-score:0.588 uniprotkb:Q08967 uniprotkb:P09620 uniprotkb:FLC1_YEAST(gene name) uniprotkb:KEX1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P19807 uniprotkb:FLC1_YEAST(gene name) uniprotkb:HNM1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P25623 uniprotkb:FLC1_YEAST(gene name) uniprotkb:SYP1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P29465 uniprotkb:FLC1_YEAST(gene name) uniprotkb:CHS3_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P50276 uniprotkb:FLC1_YEAST(gene name) uniprotkb:MUP1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P51533 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PDR10_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0112(ubiquitin reconstruction) - pubmed:23831759 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:8284879 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:Q12256 uniprotkb:FLC1_YEAST(gene name) uniprotkb:TPO4_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q08967 uniprotkb:P13134 uniprotkb:FLC1_YEAST(gene name) uniprotkb:KEX2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.55|method-score:0.49|interaction-score:0.518 uniprotkb:Q08967 uniprotkb:P25619 uniprotkb:FLC1_YEAST(gene name) uniprotkb:HSP30_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.55|method-score:0.49|interaction-score:0.518 uniprotkb:Q08967 uniprotkb:P38755 uniprotkb:FLC1_YEAST(gene name) uniprotkb:OSH7_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.55|method-score:0.49|interaction-score:0.518 uniprotkb:Q08967 uniprotkb:P53390 uniprotkb:FLC1_YEAST(gene name) uniprotkb:MEP3_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.55|method-score:0.49|interaction-score:0.518 uniprotkb:Q08967 uniprotkb:P10823 uniprotkb:FLC1_YEAST(gene name) uniprotkb:GPA2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:P35735 uniprotkb:FLC1_YEAST(gene name) uniprotkb:SFK1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:P40088 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FTR1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:24927 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:Q04383 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PLM2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:Q07651 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FMP45_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:Q12335 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PST2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.50|method-score:0.49|interaction-score:0.494 uniprotkb:Q08967 uniprotkb:P38631 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FKS1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3609308 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q08967 uniprotkb:P40989 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FKS2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3617738 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q08967 uniprotkb:P00546 uniprotkb:FLC1_YEAST(gene name) uniprotkb:CDK1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:24374311 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1276953 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q08967 uniprotkb:P40015 uniprotkb:FLC1_YEAST(gene name) uniprotkb:ISC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3606152 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q08967 uniprotkb:P46992 uniprotkb:FLC1_YEAST(gene name) uniprotkb:TOH1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616698 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q08967 uniprotkb:Q03516 uniprotkb:FLC1_YEAST(gene name) uniprotkb:RSN1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616675 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q08967 uniprotkb:P30605 uniprotkb:FLC1_YEAST(gene name) uniprotkb:ITR1_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.60|method-score:0.35|interaction-score:0.457 uniprotkb:Q08967 uniprotkb:P38310 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FTH1_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16713950 annotation-score:0.60|method-score:0.35|interaction-score:0.457 uniprotkb:Q08967 uniprotkb:P53283 uniprotkb:FLC1_YEAST(gene name) uniprotkb:TPO2_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16712632 annotation-score:0.60|method-score:0.35|interaction-score:0.457 uniprotkb:Q08967 uniprotkb:P38873 uniprotkb:FLC1_YEAST(gene name) uniprotkb:KOG1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay) - pubmed:33566094 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3460297 annotation-score:0.50|method-score:0.39|interaction-score:0.439 uniprotkb:Q08967 uniprotkb:P10614 uniprotkb:FLC1_YEAST(gene name) uniprotkb:CP51_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.55|method-score:0.35|interaction-score:0.438 uniprotkb:Q08967 uniprotkb:Q06689 uniprotkb:FLC1_YEAST(gene name) uniprotkb:YL413_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16714009 annotation-score:0.55|method-score:0.35|interaction-score:0.438 uniprotkb:Q08967 uniprotkb:P33302 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PDR5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616654 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:Q08967 uniprotkb:P02829 uniprotkb:FLC1_YEAST(gene name) uniprotkb:HSP82_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3811551 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q08967 uniprotkb:Q12230 uniprotkb:FLC1_YEAST(gene name) uniprotkb:LSP1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557|pubmed:22615397 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.16|method-score:0.63|interaction-score:0.319 uniprotkb:Q08967 uniprotkb:P26570 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PPZ1_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.16|method-score:0.49|interaction-score:0.282 uniprotkb:Q08967 uniprotkb:P32791 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FRE1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3617745 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:Q08967 uniprotkb:P17064 uniprotkb:FLC1_YEAST(gene name) uniprotkb:FCY2_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16713974 annotation-score:0.16|method-score:0.35|interaction-score:0.238 uniprotkb:Q08967 uniprotkb:P38009 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PUR92_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16714021 annotation-score:0.16|method-score:0.35|interaction-score:0.238 uniprotkb:Q08967 uniprotkb:P38720 uniprotkb:FLC1_YEAST(gene name) uniprotkb:6PGD1_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16713986 annotation-score:0.16|method-score:0.35|interaction-score:0.238 uniprotkb:Q08967 uniprotkb:P47072 uniprotkb:FLC1_YEAST(gene name) uniprotkb:YJB6_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16712692 annotation-score:0.16|method-score:0.35|interaction-score:0.238 uniprotkb:Q08967 uniprotkb:P53278 uniprotkb:FLC1_YEAST(gene name) uniprotkb:YG3A_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16712716 annotation-score:0.16|method-score:0.35|interaction-score:0.238 uniprotkb:Q08967 uniprotkb:P87284 uniprotkb:FLC1_YEAST(gene name) uniprotkb:PMP3_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:28183979 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-16713962 annotation-score:0.16|method-score:0.35|interaction-score:0.238 *************Service provided by Combinatics****************************