*************Generated from HitPredict database (15Jul2024)************* List of interactions for Q12365|BBP1|Saccharomyces cerevisiae S288C|Interactions:44 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:Q12365 uniprotkb:P53159 uniprotkb:BBP1_YEAST(gene name) uniprotkb:MPS2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0055(fluorescent resonance energy transfer)|psi-mi:MI:0096(pull down)|psi-mi:MI:0401(biochemical)|psi-mi:MI:0007(anti tag coimmunoprecipitation) - pubmed:10654940|pubmed:37968396|pubmed:20139001|pubmed:12917332|pubmed:11952896|pubmed:28356353|pubmed:32059771|pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3871072 annotation-score:0.55|method-score:0.95|interaction-score:0.725 uniprotkb:Q12365 uniprotkb:P33419 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPC29_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down) - pubmed:10654940|pubmed:28356353|pubmed:30044722|pubmed:30862629 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-3870998 annotation-score:0.55|method-score:0.81|interaction-score:0.668 uniprotkb:Q12365 uniprotkb:Q12365 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BBP1_YEAST(gene name) - - psi-mi:MI:0686(unspecified method)|psi-mi:MI:0096(pull down)|psi-mi:MI:0055(fluorescent resonance energy transfer)|psi-mi:MI:0018(two hybrid) - pubmed:11967834|pubmed:20139001|pubmed:10654940 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-3870957 annotation-score:0.55|method-score:0.70|interaction-score:0.619 uniprotkb:Q12365 uniprotkb:P40457 uniprotkb:BBP1_YEAST(gene name) uniprotkb:MLP2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down) - pubmed:24500206|pubmed:21700874|pubmed:16027220 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-2212931 annotation-score:0.55|method-score:0.68|interaction-score:0.613 uniprotkb:Q12365 uniprotkb:P32562 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CDC5_YEAST(gene name) - - psi-mi:MI:0096(pull down)|psi-mi:MI:0018(two hybrid) - pubmed:14767068|pubmed:15509790 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:644314 annotation-score:0.55|method-score:0.63|interaction-score:0.588 uniprotkb:Q12365 uniprotkb:Q07732 uniprotkb:BBP1_YEAST(gene name) uniprotkb:ADY3_YEAST(gene name) - - psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid) - pubmed:11283351|pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-16257896 annotation-score:0.55|method-score:0.63|interaction-score:0.587 uniprotkb:Q12365 uniprotkb:P32500 uniprotkb:BBP1_YEAST(gene name) uniprotkb:NDC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid) - pubmed:28356353|pubmed:30862629 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2934564 annotation-score:0.55|method-score:0.57|interaction-score:0.561 uniprotkb:Q12365 uniprotkb:P38934 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BFR1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:8913743|pubmed:19571182 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:349848 annotation-score:0.55|method-score:0.57|interaction-score:0.561 uniprotkb:Q12365 uniprotkb:P00546 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CDK1_YEAST(gene name) - - psi-mi:MI:0424(protein kinase assay)|psi-mi:MI:0415(enzymatic study) - pubmed:14574415 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:152029 annotation-score:0.55|method-score:0.52|interaction-score:0.537 uniprotkb:Q12365 uniprotkb:P52919 uniprotkb:BBP1_YEAST(gene name) uniprotkb:NBP1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16436507 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-2132993 annotation-score:0.55|method-score:0.44|interaction-score:0.493 uniprotkb:Q12365 uniprotkb:P11927 uniprotkb:BBP1_YEAST(gene name) uniprotkb:KAR1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:10654940 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-3870985 annotation-score:0.55|method-score:0.43|interaction-score:0.486 uniprotkb:Q12365 uniprotkb:P39743 uniprotkb:BBP1_YEAST(gene name) uniprotkb:RV167_YEAST(gene name) - - psi-mi:MI:0081(peptide array) - pubmed:14737190 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-488809 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:Q12365 uniprotkb:P29311 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BMH1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3611244 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12365 uniprotkb:P34730 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BMH2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3611349 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12365 uniprotkb:P38042 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CDC27_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:17634282 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:257319 annotation-score:0.55|method-score:0.39|interaction-score:0.460 uniprotkb:Q12365 uniprotkb:P36094 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPC42_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:29903865 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2446996 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12365 uniprotkb:P38863 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPC97_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:25897084 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2347393 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12365 uniprotkb:Q00684 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CDC14_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:29738528 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2447346 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12365 uniprotkb:Q07468 uniprotkb:BBP1_YEAST(gene name) uniprotkb:VAM6_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:25026036 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1254291 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12365 uniprotkb:P10591 uniprotkb:BBP1_YEAST(gene name) uniprotkb:HSP71_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3667651 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q12365 uniprotkb:P10592 uniprotkb:BBP1_YEAST(gene name) uniprotkb:HSP72_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3708819 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q12365 uniprotkb:P11484 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3778064 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P14832 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CYPH_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2882919 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P32380 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SP110_YEAST(gene name) - - psi-mi:MI:0401(biochemical) - pubmed:9585415 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0463(biogrid) biogrid:152919 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P32472 uniprotkb:BBP1_YEAST(gene name) uniprotkb:FKBP2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2883301 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P38788 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SSZ1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3789210 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P39723 uniprotkb:BBP1_YEAST(gene name) uniprotkb:MBO1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2887969 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P40433 uniprotkb:BBP1_YEAST(gene name) uniprotkb:6P21_YEAST(gene name) - - psi-mi:MI:0007(anti tag coimmunoprecipitation) - pubmed:17559233 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0471(mint) mint:6489723 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q12365 uniprotkb:P32902 uniprotkb:BBP1_YEAST(gene name) uniprotkb:RT04_YEAST(gene name) - - psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid) - pubmed:11283351 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:237448 annotation-score:0.16|method-score:0.49|interaction-score:0.282 uniprotkb:Q12365 uniprotkb:P38346 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BIT2_YEAST(gene name) - - psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid) - pubmed:11283351 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-16252456 annotation-score:0.16|method-score:0.49|interaction-score:0.282 uniprotkb:Q12365 uniprotkb:P39923 uniprotkb:BBP1_YEAST(gene name) uniprotkb:NPR2_YEAST(gene name) - - psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid) - pubmed:11283351 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-16299212 annotation-score:0.16|method-score:0.49|interaction-score:0.282 uniprotkb:Q12365 uniprotkb:P39969 uniprotkb:BBP1_YEAST(gene name) uniprotkb:BOI2_YEAST(gene name) - - psi-mi:MI:0081(peptide array) - pubmed:14737190 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-488912 annotation-score:0.16|method-score:0.42|interaction-score:0.261 uniprotkb:Q12365 uniprotkb:P33122 uniprotkb:BBP1_YEAST(gene name) uniprotkb:TYE7_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:700791 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:P34237 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CASP_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:699646 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:P42944 uniprotkb:BBP1_YEAST(gene name) uniprotkb:GZF3_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:699372 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:P46679 uniprotkb:BBP1_YEAST(gene name) uniprotkb:STB2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:700161 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:P47167 uniprotkb:BBP1_YEAST(gene name) uniprotkb:CENPK_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:17634282 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:257561 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:Q06162 uniprotkb:BBP1_YEAST(gene name) uniprotkb:NKP2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:17634282 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:257610 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:Q06629 uniprotkb:BBP1_YEAST(gene name) uniprotkb:HDA2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:22875988 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:698547 annotation-score:0.16|method-score:0.39|interaction-score:0.251 uniprotkb:Q12365 uniprotkb:P35208 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPT10_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:25228766 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1027797 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:Q12365 uniprotkb:P35209 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPT21_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:25228766 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1027992 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:Q12365 uniprotkb:Q08649 uniprotkb:BBP1_YEAST(gene name) uniprotkb:ESA1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:23572591 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:857836 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:Q12365 uniprotkb:Q04477 uniprotkb:BBP1_YEAST(gene name) uniprotkb:SPC24_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2887856 annotation-score:0.16|method-score:0.33|interaction-score:0.232 *************Service provided by Combinatics****************************