*************Generated from HitPredict database (15Jul2024)*************
List of interactions for P05231|IL6|Homo sapiens|Interactions:22
************************************************************************
Interactor A ID	Interactor B ID	Interactor A Name	Interactor B Name	Interactor A Alias	Interactor B Alias	Interaction detection methods	First author	Publications	Interactor A Taxonomy	Interactor B Taxonomy	Interaction type	Source database	Interaction identifier	Confidence score
uniprotkb:P05231	uniprotkb:P08887	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:IL6RA_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0071(molecular sieving)|psi-mi:MI:0401(biochemical)|psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0892(solid phase assay)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0091(chromatography technology)|psi-mi:MI:0040(electron microscopy)|psi-mi:MI:0077(nuclear magnetic resonance)|psi-mi:MI:0107(surface plasmon resonance)|psi-mi:MI:0411(enzyme linked immunosorbent assay)	-	pubmed:14557255|pubmed:12643274|pubmed:2788034|pubmed:8702737|pubmed:9028955|pubmed:7744001|pubmed:9694899|pubmed:14656210|pubmed:7744875|pubmed:8706672|pubmed:15895091|pubmed:28265003|pubmed:11238858	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-9007455	annotation-score:1.00|method-score:0.96|interaction-score:0.982
uniprotkb:P05231	uniprotkb:P40189	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:IL6RB_HUMAN(gene name)	-	-	psi-mi:MI:0114(x-ray crystallography)|psi-mi:MI:0013(biophysical)|psi-mi:MI:0091(chromatography technology)|psi-mi:MI:0040(electron microscopy)	-	pubmed:11251120|pubmed:7744001|pubmed:15895091	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:156275	annotation-score:1.00|method-score:0.71|interaction-score:0.845
uniprotkb:P05231	uniprotkb:Q04206	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:TF65_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:19122653|pubmed:20457835|pubmed:21602809|pubmed:22096605|pubmed:24012417|pubmed:25888873	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.60|method-score:0.87|interaction-score:0.721
uniprotkb:P05231	uniprotkb:Q92673	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:SORL_HUMAN(gene name)	-	-	psi-mi:MI:0107(surface plasmon resonance)	-	pubmed:28265003	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-25300070	annotation-score:1.00|method-score:0.46|interaction-score:0.681
uniprotkb:P05231	uniprotkb:P17676	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:CEBPB_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:12706815|pubmed:24012417	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.60|method-score:0.57|interaction-score:0.584
uniprotkb:P05231	uniprotkb:Q04864	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:REL_HUMAN(gene name)	-	-	psi-mi:MI:0412(electrophoretic mobility supershift assay)|psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:1372388|pubmed:19122653	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:185908	annotation-score:0.60|method-score:0.57|interaction-score:0.584
uniprotkb:P05231	uniprotkb:Q99523	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:SORT_HUMAN(gene name)	-	-	psi-mi:MI:0107(surface plasmon resonance)|psi-mi:MI:0030(cross-linking study)	-	pubmed:25401472	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-25396692	annotation-score:0.60|method-score:0.52|interaction-score:0.561
uniprotkb:P05231	uniprotkb:Q99962	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:SH3G2_HUMAN(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0398(two hybrid pooling approach)	-	pubmed:16169070	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-734853	annotation-score:0.55|method-score:0.49|interaction-score:0.518
uniprotkb:P05231	uniprotkb:Q5D1E8	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:ZC12A_HUMAN(gene name)	-	-	psi-mi:MI:0096(pull down)	-	pubmed:29743536	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:2691928	annotation-score:0.55|method-score:0.42|interaction-score:0.480
uniprotkb:P05231	uniprotkb:Q8IXL6	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:FA20C_HUMAN(gene name)	-	-	psi-mi:MI:0424(protein kinase assay)	-	pubmed:26091039	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0217(phosphorylation reaction)	psi-mi:MI:0469(intact)	intact:EBI-13915421	annotation-score:0.55|method-score:0.42|interaction-score:0.480
uniprotkb:P05231	uniprotkb:P19838	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:NFKB1_HUMAN(gene name)	-	-	psi-mi:MI:0412(electrophoretic mobility supershift assay)	-	pubmed:1372388	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:117166	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P05231	uniprotkb:Q09472	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:EP300_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:24012417	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P05231	uniprotkb:Q6N021	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:TET2_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:26287468	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P05231	uniprotkb:Q92793	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:CBP_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:24012417	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P05231	uniprotkb:P01023	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:A2MG_HUMAN(gene name)	-	-	psi-mi:MI:0404(comigration in non denaturing gel electrophoresis)	-	pubmed:9780213	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:185302	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:P02741	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:CRP_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:14656210	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:156247	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:P10914	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:IRF1_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:24012417	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:P13725	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:ONCM_HUMAN(gene name)	-	-	psi-mi:MI:0401(biochemical)	-	pubmed:10681548	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0465(dip)	dip:DIP-10065E	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:P42224	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:STAT1_HUMAN(gene name)	-	-	psi-mi:MI:0007(anti tag coimmunoprecipitation)	-	pubmed:24012417	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:649196	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:Q06330	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:SUH_HUMAN(gene name)	-	-	psi-mi:MI:0412(electrophoretic mobility supershift assay)	-	pubmed:10373597	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0974(innatedb)	innatedb:156254	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05231	uniprotkb:Q05516	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:ZBT16_HUMAN(gene name)	-	-	psi-mi:MI:0398(two hybrid pooling approach)	-	pubmed:16169070	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0469(intact)	intact:EBI-736949	annotation-score:0.55|method-score:0.35|interaction-score:0.438
uniprotkb:P05231	uniprotkb:P54578	uniprotkb:IL6_HUMAN(gene name)	uniprotkb:UBP14_HUMAN(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:35549778	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3401109	annotation-score:0.16|method-score:0.38|interaction-score:0.249
*************Service provided by Combinatics****************************