*************Generated from HitPredict database (15Jul2024)************* List of interactions for P46678|TFC5|Saccharomyces cerevisiae S288C|Interactions:45 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:P46678 uniprotkb:P29056 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TF3B_YEAST(gene name) - - psi-mi:MI:0404(comigration in non denaturing gel electrophoresis)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down) - pubmed:7568218|pubmed:24277937|pubmed:8662956|pubmed:26055328|pubmed:16551611|pubmed:19086269|pubmed:30593915|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3611801 annotation-score:1.00|method-score:0.93|interaction-score:0.966 uniprotkb:P46678 uniprotkb:P13393 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TBP_YEAST(gene name) - - psi-mi:MI:0404(comigration in non denaturing gel electrophoresis)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down) - pubmed:7568218|pubmed:24277937|pubmed:8662956|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3602499 annotation-score:1.00|method-score:0.80|interaction-score:0.896 uniprotkb:P46678 uniprotkb:P33339 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TFC4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down) - pubmed:11739742|pubmed:10559229|pubmed:24277937|pubmed:12930823|pubmed:30247619 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2591734 annotation-score:0.55|method-score:0.86|interaction-score:0.686 uniprotkb:P46678 uniprotkb:P22276 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:30593915|pubmed:26055328|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616381 annotation-score:0.60|method-score:0.68|interaction-score:0.640 uniprotkb:P46678 uniprotkb:P04051 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:1993618 annotation-score:0.60|method-score:0.60|interaction-score:0.601 uniprotkb:P46678 uniprotkb:P36121 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:26055328|pubmed:37968396|pubmed:21536656 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:563170 annotation-score:0.50|method-score:0.68|interaction-score:0.585 uniprotkb:P46678 uniprotkb:P32349 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:28096404|pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616376 annotation-score:0.55|method-score:0.57|interaction-score:0.559 uniprotkb:P46678 uniprotkb:P29055 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TF2B_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37863410 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3641311 annotation-score:0.80|method-score:0.38|interaction-score:0.553 uniprotkb:P46678 uniprotkb:P54000 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SUB1_YEAST(gene name) - - psi-mi:MI:0047(far western blotting) - pubmed:19706510 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:343592 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:P46678 uniprotkb:P07703 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616378 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P20434 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAB1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616384 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P20435 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAB2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616379 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P28000 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAC2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616374 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P32910 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC6_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616383 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P35718 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC8_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616385 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P40422 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAB4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3612295 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P46678 uniprotkb:P02309 uniprotkb:TFC5_YEAST(gene name) uniprotkb:H4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:22199229 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:633549 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P17890 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC7_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616382 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P22139 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPAB5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616375 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P25441 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3593941 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P32367 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TFC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3605465 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P34111 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TFC3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:30053100 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2600087 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P47076 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC9_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3611819 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:Q04307 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RPC10_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616377 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:Q06339 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TFC6_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:30593915 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:2556140 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P46678 uniprotkb:P22216 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RAD53_YEAST(gene name) - - psi-mi:MI:1313(proximity labelling technology) - pubmed:37766847 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3574977 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:P46678 uniprotkb:P02293 uniprotkb:TFC5_YEAST(gene name) uniprotkb:H2B1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884858 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P46678 uniprotkb:P36124 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SET3_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2887220 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P46678 uniprotkb:P61830 uniprotkb:TFC5_YEAST(gene name) uniprotkb:H3_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884222 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P46678 uniprotkb:P10591 uniprotkb:TFC5_YEAST(gene name) uniprotkb:HSP71_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3770984 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:P10592 uniprotkb:TFC5_YEAST(gene name) uniprotkb:HSP72_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3793194 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:P11484 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3778088 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:P32589 uniprotkb:TFC5_YEAST(gene name) uniprotkb:HSP7F_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3804335 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:P40150 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SSB2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3797278 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:Q02206 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RSC4_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2886536 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P46678 uniprotkb:P11792 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SCH9_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:25970584 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:1277731 annotation-score:0.16|method-score:0.42|interaction-score:0.261 uniprotkb:P46678 uniprotkb:P07884 uniprotkb:TFC5_YEAST(gene name) uniprotkb:MOD5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:23898186 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1113342 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P46678 uniprotkb:P38074 uniprotkb:TFC5_YEAST(gene name) uniprotkb:HMT1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:23268696 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:796445 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P46678 uniprotkb:P53040 uniprotkb:TFC5_YEAST(gene name) uniprotkb:TAF6_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:12052880 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:136052 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P46678 uniprotkb:Q12510 uniprotkb:TFC5_YEAST(gene name) uniprotkb:CMR1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:22199229 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:635071 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P46678 uniprotkb:P25491 uniprotkb:TFC5_YEAST(gene name) uniprotkb:MAS5_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3763779 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P46678 uniprotkb:P32447 uniprotkb:TFC5_YEAST(gene name) uniprotkb:ASF1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2881951 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P46678 uniprotkb:P38788 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SSZ1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3789226 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P46678 uniprotkb:Q06677 uniprotkb:TFC5_YEAST(gene name) uniprotkb:SWA2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3758129 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P46678 uniprotkb:Q12495 uniprotkb:TFC5_YEAST(gene name) uniprotkb:RLF2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2882508 annotation-score:0.16|method-score:0.33|interaction-score:0.232 *************Service provided by Combinatics****************************