*************Generated from HitPredict database (15Jul2024)************* List of interactions for Q04089|DOT1|Saccharomyces cerevisiae S288C|Interactions:31 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:Q04089 uniprotkb:P61830 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H3_YEAST(gene name) - - psi-mi:MI:0401(biochemical)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0415(enzymatic study)|psi-mi:MI:0096(pull down)|psi-mi:MI:0114(x-ray crystallography) - pubmed:12080090|pubmed:12097318|pubmed:12086673|pubmed:25965993|pubmed:29339748|pubmed:18158898|pubmed:33479126|pubmed:18511943|pubmed:20678485 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0463(biogrid) biogrid:615728 annotation-score:1.00|method-score:0.95|interaction-score:0.973 uniprotkb:Q04089 uniprotkb:P02309 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0096(pull down)|psi-mi:MI:0114(x-ray crystallography)|psi-mi:MI:0415(enzymatic study)|psi-mi:MI:0676(tandem affinity purification) - pubmed:18158898|pubmed:29339748|pubmed:33479126|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2883133 annotation-score:0.90|method-score:0.79|interaction-score:0.844 uniprotkb:Q04089 uniprotkb:P02293 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H2B1_YEAST(gene name) - - psi-mi:MI:0096(pull down)|psi-mi:MI:0114(x-ray crystallography) - pubmed:29339748|pubmed:33479126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0463(biogrid) biogrid:3017587 annotation-score:1.00|method-score:0.57|interaction-score:0.755 uniprotkb:Q04089 uniprotkb:P0CG63 uniprotkb:DOT1_YEAST(gene name) uniprotkb:UBI4P_YEAST(gene name) - - psi-mi:MI:0047(far western blotting)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:20678485 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:478722 annotation-score:0.90|method-score:0.52|interaction-score:0.687 uniprotkb:Q04089 uniprotkb:P02294 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H2B2_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:29339748 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2400765 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:Q04089 uniprotkb:P04911 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H2A1_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:29339748 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2400762 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:Q04089 uniprotkb:P04912 uniprotkb:DOT1_YEAST(gene name) uniprotkb:H2A2_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:29339748 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2400763 annotation-score:1.00|method-score:0.42|interaction-score:0.647 uniprotkb:Q04089 uniprotkb:Q04089 uniprotkb:DOT1_YEAST(gene name) uniprotkb:DOT1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2883133 annotation-score:1.00|method-score:0.33|interaction-score:0.575 uniprotkb:Q04089 uniprotkb:P36104 uniprotkb:DOT1_YEAST(gene name) uniprotkb:SWD2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0006(anti bait coimmunoprecipitation) - pubmed:18083099 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-1569086 annotation-score:0.60|method-score:0.44|interaction-score:0.515 uniprotkb:Q04089 uniprotkb:Q12159 uniprotkb:DOT1_YEAST(gene name) uniprotkb:YRA1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352330 annotation-score:0.60|method-score:0.44|interaction-score:0.515 uniprotkb:Q04089 uniprotkb:P38203 uniprotkb:DOT1_YEAST(gene name) uniprotkb:LSM2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:10900456 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0471(mint) mint:51219 annotation-score:0.60|method-score:0.43|interaction-score:0.508 uniprotkb:Q04089 uniprotkb:P16892 uniprotkb:DOT1_YEAST(gene name) uniprotkb:FUS3_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:198381 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:Q04089 uniprotkb:P32485 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HOG1_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:38270553 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3648109 annotation-score:0.60|method-score:0.42|interaction-score:0.501 uniprotkb:Q04089 uniprotkb:P23291 uniprotkb:DOT1_YEAST(gene name) uniprotkb:KC11_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:201393 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:Q04089 uniprotkb:Q06440 uniprotkb:DOT1_YEAST(gene name) uniprotkb:CORO_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352347 annotation-score:0.50|method-score:0.44|interaction-score:0.470 uniprotkb:Q04089 uniprotkb:Q06704 uniprotkb:DOT1_YEAST(gene name) uniprotkb:IMH1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352398 annotation-score:0.50|method-score:0.44|interaction-score:0.470 uniprotkb:Q04089 uniprotkb:Q08746 uniprotkb:DOT1_YEAST(gene name) uniprotkb:RRS1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352381 annotation-score:0.50|method-score:0.44|interaction-score:0.470 uniprotkb:Q04089 uniprotkb:P29055 uniprotkb:DOT1_YEAST(gene name) uniprotkb:TF2B_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37863410 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3640039 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q04089 uniprotkb:Q12158 uniprotkb:DOT1_YEAST(gene name) uniprotkb:SCC1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37486771 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3625771 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q04089 uniprotkb:P10591 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSP71_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3669313 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q04089 uniprotkb:P10592 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSP72_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3709868 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q04089 uniprotkb:P11484 uniprotkb:DOT1_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3687363 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q04089 uniprotkb:P32589 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSP7F_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3724526 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q04089 uniprotkb:P38911 uniprotkb:DOT1_YEAST(gene name) uniprotkb:FKBP3_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2883133 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:Q04089 uniprotkb:P15108 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSC82_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3733907 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:Q04089 uniprotkb:P39987 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSP7E_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3701675 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:Q04089 uniprotkb:P40485 uniprotkb:DOT1_YEAST(gene name) uniprotkb:SLM1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352312 annotation-score:0.16|method-score:0.44|interaction-score:0.269 uniprotkb:Q04089 uniprotkb:P50942 uniprotkb:DOT1_YEAST(gene name) uniprotkb:INP52_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:2352364 annotation-score:0.16|method-score:0.44|interaction-score:0.269 uniprotkb:Q04089 uniprotkb:P46988 uniprotkb:DOT1_YEAST(gene name) uniprotkb:PFD1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3737483 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:Q04089 uniprotkb:Q12329 uniprotkb:DOT1_YEAST(gene name) uniprotkb:HSP42_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3750599 annotation-score:0.16|method-score:0.33|interaction-score:0.232 *************Service provided by Combinatics****************************