*************Generated from HitPredict database (15Jul2024)************* List of interactions for P53096|HOS2|Saccharomyces cerevisiae S288C|Interactions:45 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:P53096 uniprotkb:P25357 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SNT1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434|pubmed:16429126|pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-788258 annotation-score:1.00|method-score:0.79|interaction-score:0.887 uniprotkb:P53096 uniprotkb:P36124 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SET3_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434|pubmed:16429126|pubmed:19379692|pubmed:35234136|pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-794754 annotation-score:0.60|method-score:0.88|interaction-score:0.727 uniprotkb:P53096 uniprotkb:P38262 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SIF2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434|pubmed:11805826|pubmed:16429126|pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.84|interaction-score:0.712 uniprotkb:P53096 uniprotkb:P14832 uniprotkb:HOS2_YEAST(gene name) uniprotkb:CYPH_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434|pubmed:16429126|pubmed:15643056|pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.84|interaction-score:0.709 uniprotkb:P53096 uniprotkb:P40480 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HOS4_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434|pubmed:16429126|pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-799151 annotation-score:0.60|method-score:0.79|interaction-score:0.687 uniprotkb:P53096 uniprotkb:P14922 uniprotkb:HOS2_YEAST(gene name) uniprotkb:CYC8_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0006(anti bait coimmunoprecipitation)|psi-mi:MI:0096(pull down) - pubmed:14525981|pubmed:11069890 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-1370731 annotation-score:0.60|method-score:0.65|interaction-score:0.623 uniprotkb:P53096 uniprotkb:P50111 uniprotkb:HOS2_YEAST(gene name) uniprotkb:ZDS1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11805826|pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-803477 annotation-score:0.60|method-score:0.64|interaction-score:0.621 uniprotkb:P53096 uniprotkb:P53096 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HOS2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:1.00|method-score:0.33|interaction-score:0.575 uniprotkb:P53096 uniprotkb:Q02959 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HOS3_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:1.00|method-score:0.33|interaction-score:0.575 uniprotkb:P53096 uniprotkb:P39076 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPB_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.54|interaction-score:0.571 uniprotkb:P53096 uniprotkb:P42943 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPH_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.54|interaction-score:0.571 uniprotkb:P53096 uniprotkb:P61830 uniprotkb:HOS2_YEAST(gene name) uniprotkb:H3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0096(pull down) - pubmed:19379692 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-2348272 annotation-score:0.60|method-score:0.48|interaction-score:0.534 uniprotkb:P53096 uniprotkb:P39079 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPZ_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:37968396|pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.54|interaction-score:0.521 uniprotkb:P53096 uniprotkb:P53685 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HST1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:11711434 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:134187 annotation-score:0.60|method-score:0.44|interaction-score:0.515 uniprotkb:P53096 uniprotkb:P28707 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SBA1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:21777812 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:557083 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:P53096 uniprotkb:P04050 uniprotkb:HOS2_YEAST(gene name) uniprotkb:RPB1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:20670892 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:463331 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P53096 uniprotkb:P29055 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TF2B_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37863410 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3640249 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P53096 uniprotkb:P38827 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SET1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:12096120 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:351892 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:P53096 uniprotkb:P02294 uniprotkb:HOS2_YEAST(gene name) uniprotkb:H2B2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P02309 uniprotkb:HOS2_YEAST(gene name) uniprotkb:H4_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P02994 uniprotkb:HOS2_YEAST(gene name) uniprotkb:EF1A_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P07259 uniprotkb:HOS2_YEAST(gene name) uniprotkb:PYR1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P10592 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HSP72_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P11484 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P38080 uniprotkb:HOS2_YEAST(gene name) uniprotkb:AKL1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P38144 uniprotkb:HOS2_YEAST(gene name) uniprotkb:ISW1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P38873 uniprotkb:HOS2_YEAST(gene name) uniprotkb:KOG1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P41940 uniprotkb:HOS2_YEAST(gene name) uniprotkb:MPG1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P47079 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPQ_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P53091 uniprotkb:HOS2_YEAST(gene name) uniprotkb:MCM6_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:Q00684 uniprotkb:HOS2_YEAST(gene name) uniprotkb:CDC14_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:Q03940 uniprotkb:HOS2_YEAST(gene name) uniprotkb:RUVB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:Q06266 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TOS4_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:P53096 uniprotkb:P53919 uniprotkb:HOS2_YEAST(gene name) uniprotkb:NAF1_YEAST(gene name) - - psi-mi:MI:0397(two hybrid array) - pubmed:14690591 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-858478 annotation-score:0.55|method-score:0.35|interaction-score:0.438 uniprotkb:P53096 uniprotkb:P32558 uniprotkb:HOS2_YEAST(gene name) uniprotkb:SPT16_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:33963860 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3024803 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:P53096 uniprotkb:P40850 uniprotkb:HOS2_YEAST(gene name) uniprotkb:MKT1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P53096 uniprotkb:Q12490 uniprotkb:HOS2_YEAST(gene name) uniprotkb:YB11B_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.55|method-score:0.33|interaction-score:0.426 uniprotkb:P53096 uniprotkb:P12612 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPA_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:P19882 uniprotkb:HOS2_YEAST(gene name) uniprotkb:HSP60_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:16429126 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-795957 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:P39077 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPG_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:P39078 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPD_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:P40413 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TCPE_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:P47035 uniprotkb:HOS2_YEAST(gene name) uniprotkb:NET1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P53096 uniprotkb:Q02208 uniprotkb:HOS2_YEAST(gene name) uniprotkb:TOF2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:21179020 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-2884518 annotation-score:0.50|method-score:0.33|interaction-score:0.407 *************Service provided by Combinatics****************************