*************Generated from HitPredict database (11Aug2025)*************
List of interactions for P05373|HEM2|Saccharomyces cerevisiae S288C|Interactions:20
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Interactor A ID	Interactor B ID	Interactor A Name	Interactor B Name	Interactor A Alias	Interactor B Alias	Interaction detection methods	First author	Publications	Interactor A Taxonomy	Interactor B Taxonomy	Interaction type	Source database	Interaction identifier	Confidence score
uniprotkb:P05373	uniprotkb:P05373	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:HEM2_YEAST(gene name)	-	-	psi-mi:MI:0018(two hybrid)|psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction)	-	pubmed:11283351|pubmed:18467557	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)	psi-mi:MI:0471(mint)	mint:6665292	annotation-score:1.00|method-score:0.63|interaction-score:0.791
uniprotkb:P05373	uniprotkb:P15108	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:HSC82_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:31399574|pubmed:37295430	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3556734	annotation-score:0.60|method-score:0.57|interaction-score:0.584
uniprotkb:P05373	uniprotkb:Q02821	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:IMA1_YEAST(gene name)	-	-	psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid)	-	pubmed:11283351	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:237779	annotation-score:0.55|method-score:0.49|interaction-score:0.518
uniprotkb:P05373	uniprotkb:P0CG63	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:UBI4P_YEAST(gene name)	-	-	psi-mi:MI:0096(pull down)	-	pubmed:38803224	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:3713853	annotation-score:0.60|method-score:0.42|interaction-score:0.501
uniprotkb:P05373	uniprotkb:P02829	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:HSP82_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:31399574	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2598912	annotation-score:0.60|method-score:0.38|interaction-score:0.479
uniprotkb:P05373	uniprotkb:P35169	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:TOR1_YEAST(gene name)	-	-	psi-mi:MI:0090(protein complementation assay)	-	pubmed:33566094	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:3460501	annotation-score:0.55|method-score:0.39|interaction-score:0.460
uniprotkb:P05373	uniprotkb:P38873	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:KOG1_YEAST(gene name)	-	-	psi-mi:MI:0090(protein complementation assay)	-	pubmed:33566094	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:3460243	annotation-score:0.55|method-score:0.39|interaction-score:0.460
uniprotkb:P05373	uniprotkb:P25294	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:SIS1_YEAST(gene name)	-	-	psi-mi:MI:1313(proximity labelling technology)	-	pubmed:37845327	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3658569	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:P29055	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:TF2B_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37863410	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3638865	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:P32643	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:TMT1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37968396	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3608943	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:P38764	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:RPN1_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:18757749	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:339963	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:P43588	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:RPN11_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:18757749	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:340708	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:Q12149	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:RRP6_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:28539363	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:2455277	annotation-score:0.55|method-score:0.38|interaction-score:0.458
uniprotkb:P05373	uniprotkb:P10591	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:HSP71_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-788064	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P05373	uniprotkb:P10592	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:HSP72_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:16429126	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-788064	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P05373	uniprotkb:P11484	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:SSB1_YEAST(gene name)	-	-	psi-mi:MI:0676(tandem affinity purification)	-	pubmed:19536198	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0469(intact)	intact:EBI-3689070	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P05373	uniprotkb:P40150	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:SSB2_YEAST(gene name)	-	-	psi-mi:MI:0401(biochemical)	-	pubmed:23332755	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0914(association)	psi-mi:MI:0463(biogrid)	biogrid:1061025	annotation-score:0.60|method-score:0.33|interaction-score:0.445
uniprotkb:P05373	uniprotkb:P38987	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:TEM1_YEAST(gene name)	-	-	psi-mi:MI:0398(two hybrid pooling approach)|psi-mi:MI:0018(two hybrid)	-	pubmed:11283351	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)	psi-mi:MI:0463(biogrid)	biogrid:237663	annotation-score:0.16|method-score:0.49|interaction-score:0.282
uniprotkb:P05373	uniprotkb:P38181	uniprotkb:HEM2_YEAST(gene name)	uniprotkb:NU170_YEAST(gene name)	-	-	psi-mi:MI:0004(affinity chromatography technology)	-	pubmed:37358474	taxid:559292(Saccharomyces cerevisiae S288C)	taxid:559292(Saccharomyces cerevisiae S288C)	psi-mi:MI:0915(physical association)	psi-mi:MI:0463(biogrid)	biogrid:3674724	annotation-score:0.16|method-score:0.38|interaction-score:0.249
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