*************Generated from HitPredict database (15Jul2024)************* List of interactions for P21691|SIR1|Saccharomyces cerevisiae S288C|Interactions:21 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:P21691 uniprotkb:P54784 uniprotkb:SIR1_YEAST(gene name) uniprotkb:ORC1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0114(x-ray crystallography) - pubmed:8622770|pubmed:12198162|pubmed:14701749|pubmed:9872946|pubmed:15932939|pubmed:19029247|pubmed:15937111 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-16211046 annotation-score:1.00|method-score:0.95|interaction-score:0.972 uniprotkb:P21691 uniprotkb:P06701 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SIR3_YEAST(gene name) - - psi-mi:MI:0007(anti tag coimmunoprecipitation)|psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down) - pubmed:11805837|pubmed:28188183|pubmed:19029247 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-16282584 annotation-score:1.00|method-score:0.74|interaction-score:0.860 uniprotkb:P21691 uniprotkb:P11978 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SIR4_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0096(pull down) - pubmed:8622770|pubmed:14701749|pubmed:25631822|pubmed:28188183|pubmed:21822217|pubmed:22654676 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-16211023 annotation-score:0.55|method-score:0.88|interaction-score:0.696 uniprotkb:P21691 uniprotkb:Q12495 uniprotkb:SIR1_YEAST(gene name) uniprotkb:RLF2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0018(two hybrid)|psi-mi:MI:0019(coimmunoprecipitation)|psi-mi:MI:0096(pull down) - pubmed:12975325 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:141088 annotation-score:0.55|method-score:0.57|interaction-score:0.561 uniprotkb:P21691 uniprotkb:P40150 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SSB2_YEAST(gene name) - - psi-mi:MI:0401(biochemical)|psi-mi:MI:0676(tandem affinity purification) - pubmed:23332755|pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3722094 annotation-score:0.50|method-score:0.51|interaction-score:0.504 uniprotkb:P21691 uniprotkb:P06700 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SIR2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:17043313 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0469(intact) intact:EBI-2212712 annotation-score:0.55|method-score:0.44|interaction-score:0.493 uniprotkb:P21691 uniprotkb:P11484 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3783687 annotation-score:0.50|method-score:0.48|interaction-score:0.489 uniprotkb:P21691 uniprotkb:P32833 uniprotkb:SIR1_YEAST(gene name) uniprotkb:ORC2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:14701749 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:139737 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P21691 uniprotkb:P54790 uniprotkb:SIR1_YEAST(gene name) uniprotkb:ORC3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:14701749 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:139738 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:P21691 uniprotkb:P10591 uniprotkb:SIR1_YEAST(gene name) uniprotkb:HSP71_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3677138 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P21691 uniprotkb:P10592 uniprotkb:SIR1_YEAST(gene name) uniprotkb:HSP72_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3715322 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P21691 uniprotkb:P32589 uniprotkb:SIR1_YEAST(gene name) uniprotkb:HSP7F_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3729634 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:P21691 uniprotkb:P11710 uniprotkb:SIR1_YEAST(gene name) uniprotkb:FUS1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0398(two hybrid pooling approach) - pubmed:11743162|pubmed:19841731 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0471(mint) mint:7754229 annotation-score:0.16|method-score:0.64|interaction-score:0.323 uniprotkb:P21691 uniprotkb:Q96VH3 uniprotkb:SIR1_YEAST(gene name) uniprotkb:YC021_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6665292 annotation-score:0.16|method-score:0.49|interaction-score:0.282 uniprotkb:P21691 uniprotkb:P38788 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SSZ1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3791660 annotation-score:0.16|method-score:0.48|interaction-score:0.279 uniprotkb:P21691 uniprotkb:P40016 uniprotkb:SIR1_YEAST(gene name) uniprotkb:RPN3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0676(tandem affinity purification) - pubmed:16554755 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:1983379 annotation-score:0.16|method-score:0.44|interaction-score:0.269 uniprotkb:P21691 uniprotkb:P53266 uniprotkb:SIR1_YEAST(gene name) uniprotkb:SHY1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:23979592 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:1112150 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P21691 uniprotkb:Q00684 uniprotkb:SIR1_YEAST(gene name) uniprotkb:CDC14_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:21127052 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:511776 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:P21691 uniprotkb:P39101 uniprotkb:SIR1_YEAST(gene name) uniprotkb:CAJ1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3654130 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P21691 uniprotkb:P39987 uniprotkb:SIR1_YEAST(gene name) uniprotkb:HSP7E_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3703163 annotation-score:0.16|method-score:0.33|interaction-score:0.232 uniprotkb:P21691 uniprotkb:P46988 uniprotkb:SIR1_YEAST(gene name) uniprotkb:PFD1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3738683 annotation-score:0.16|method-score:0.33|interaction-score:0.232 *************Service provided by Combinatics****************************