*************Generated from HitPredict database (15Jul2024)************* List of interactions for Q12200|NPC1|Saccharomyces cerevisiae S288C|Interactions:41 ************************************************************************ Interactor A ID Interactor B ID Interactor A Name Interactor B Name Interactor A Alias Interactor B Alias Interaction detection methods First author Publications Interactor A Taxonomy Interactor B Taxonomy Interaction type Source database Interaction identifier Confidence score uniprotkb:Q12200 uniprotkb:P33302 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PDR5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology)|psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0676(tandem affinity purification)|psi-mi:MI:0112(ubiquitin reconstruction) - pubmed:23831759 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association)|psi-mi:MI:0407(direct interaction) psi-mi:MI:0471(mint) mint:8284879 annotation-score:0.60|method-score:0.57|interaction-score:0.582 uniprotkb:Q12200 uniprotkb:P40312 uniprotkb:NPC1_YEAST(gene name) uniprotkb:CYB5_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3573408 annotation-score:0.60|method-score:0.51|interaction-score:0.552 uniprotkb:Q12200 uniprotkb:P32568 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SNQ2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0112(ubiquitin reconstruction) - pubmed:23831759 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:8284879 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q12200 uniprotkb:P38929 uniprotkb:NPC1_YEAST(gene name) uniprotkb:ATC2_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.60|method-score:0.49|interaction-score:0.541 uniprotkb:Q12200 uniprotkb:P35179 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SC61G_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3573399 annotation-score:0.55|method-score:0.51|interaction-score:0.529 uniprotkb:Q12200 uniprotkb:Q03579 uniprotkb:NPC1_YEAST(gene name) uniprotkb:LIP1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid)|psi-mi:MI:0004(affinity chromatography technology) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3573398 annotation-score:0.55|method-score:0.51|interaction-score:0.529 uniprotkb:Q12200 uniprotkb:Q12038 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SRO7_YEAST(gene name) - - psi-mi:MI:0090(protein complementation assay)|psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction)|psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.55|method-score:0.49|interaction-score:0.518 uniprotkb:Q12200 uniprotkb:P14906 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SEC63_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:29659649 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2450885 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P32915 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SC61A_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573400 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P38353 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SSH1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573401 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P38703 uniprotkb:NPC1_YEAST(gene name) uniprotkb:LAG1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573404 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P40857 uniprotkb:NPC1_YEAST(gene name) uniprotkb:HACD_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573394 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P41543 uniprotkb:NPC1_YEAST(gene name) uniprotkb:OST1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573405 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P52870 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SC6B1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573402 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:P52871 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SC6B2_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573403 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:Q12746 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PGA3_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573393 annotation-score:0.60|method-score:0.39|interaction-score:0.481 uniprotkb:Q12200 uniprotkb:Q12408 uniprotkb:NPC1_YEAST(gene name) uniprotkb:NPC2_YEAST(gene name) - - psi-mi:MI:0096(pull down) - pubmed:31543266 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:2609248 annotation-score:0.55|method-score:0.42|interaction-score:0.480 uniprotkb:Q12200 uniprotkb:P11491 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PPB_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616080 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P25371 uniprotkb:NPC1_YEAST(gene name) uniprotkb:ADP1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3614057 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P32366 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VA0D_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616010 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P32563 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VPP1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616159 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P43585 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VTC2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616107 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P47075 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VTC4_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3613942 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P48836 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VATG_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616211 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:Q02725 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VTC3_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3613907 annotation-score:0.60|method-score:0.38|interaction-score:0.479 uniprotkb:Q12200 uniprotkb:P38374 uniprotkb:NPC1_YEAST(gene name) uniprotkb:YSY6_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573396 annotation-score:0.55|method-score:0.39|interaction-score:0.460 uniprotkb:Q12200 uniprotkb:P27514 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PHO91_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3613927 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12200 uniprotkb:P32386 uniprotkb:NPC1_YEAST(gene name) uniprotkb:YBT1_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616031 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12200 uniprotkb:P32610 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VATD_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3616249 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12200 uniprotkb:P36027 uniprotkb:NPC1_YEAST(gene name) uniprotkb:MID2_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3613903 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12200 uniprotkb:P38966 uniprotkb:NPC1_YEAST(gene name) uniprotkb:VTC5_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3614014 annotation-score:0.55|method-score:0.38|interaction-score:0.458 uniprotkb:Q12200 uniprotkb:P32793 uniprotkb:NPC1_YEAST(gene name) uniprotkb:YSC84_YEAST(gene name) - - psi-mi:MI:0081(peptide array) - pubmed:14737190 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-488609 annotation-score:0.50|method-score:0.42|interaction-score:0.457 uniprotkb:Q12200 uniprotkb:P43603 uniprotkb:NPC1_YEAST(gene name) uniprotkb:LSB3_YEAST(gene name) - - psi-mi:MI:0081(peptide array) - pubmed:14737190 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0469(intact) intact:EBI-489009 annotation-score:0.50|method-score:0.42|interaction-score:0.457 uniprotkb:Q12200 uniprotkb:P11484 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SSB1_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3781446 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q12200 uniprotkb:P40150 uniprotkb:NPC1_YEAST(gene name) uniprotkb:SSB2_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3799622 annotation-score:0.60|method-score:0.33|interaction-score:0.445 uniprotkb:Q12200 uniprotkb:Q12161 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PSH1_YEAST(gene name) - - psi-mi:MI:0018(two hybrid) - pubmed:37440478 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:3573406 annotation-score:0.50|method-score:0.39|interaction-score:0.439 uniprotkb:Q12200 uniprotkb:P29055 uniprotkb:NPC1_YEAST(gene name) uniprotkb:TF2B_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37863410 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3641452 annotation-score:0.50|method-score:0.38|interaction-score:0.437 uniprotkb:Q12200 uniprotkb:P32590 uniprotkb:NPC1_YEAST(gene name) uniprotkb:HSP79_YEAST(gene name) - - psi-mi:MI:0676(tandem affinity purification) - pubmed:19536198 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0914(association) psi-mi:MI:0469(intact) intact:EBI-3776867 annotation-score:0.50|method-score:0.33|interaction-score:0.407 uniprotkb:Q12200 uniprotkb:P53170 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PDK2_YEAST(gene name) - - psi-mi:MI:0415(enzymatic study) - pubmed:16319894 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0407(direct interaction) psi-mi:MI:0463(biogrid) biogrid:201717 annotation-score:0.16|method-score:0.42|interaction-score:0.261 uniprotkb:Q12200 uniprotkb:P06704 uniprotkb:NPC1_YEAST(gene name) uniprotkb:CDC31_YEAST(gene name) - - psi-mi:MI:0004(affinity chromatography technology) - pubmed:37968396 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0463(biogrid) biogrid:3607372 annotation-score:0.16|method-score:0.38|interaction-score:0.249 uniprotkb:Q12200 uniprotkb:P25584 uniprotkb:NPC1_YEAST(gene name) uniprotkb:PEX34_YEAST(gene name) - - psi-mi:MI:0111(dihydrofolate reductase reconstruction) - pubmed:18467557 taxid:559292(Saccharomyces cerevisiae S288C) taxid:559292(Saccharomyces cerevisiae S288C) psi-mi:MI:0915(physical association) psi-mi:MI:0471(mint) mint:6796998 annotation-score:0.16|method-score:0.35|interaction-score:0.238 *************Service provided by Combinatics****************************