Protein: TEC
Tyrosine-protein kinase Tec (EC 2.7.10.2)

Gene: TEC
Organism: Homo sapiens
Interactions: 69
UniProt ID: P42680

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005543 - phospholipid binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

499242

KIT
Mast/stem cell growth factor receptor Kit

3

20

Small-scale

0.870

High

789005

DOK1
Docking protein 1

2

20

Small-scale

0.825

High

181816

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.783

High

238380

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.768

High

788998

ANR54
Ankyrin repeat domain-containing protein 54

2

15

High-throughput

0.705

High

441460

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

788991

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.692

High

788974

FRK
Tyrosine-protein kinase FRK

1

19

High-throughput

0.691

High

788980

SEC13
Protein SEC13 homolog

1

2

High-throughput

0.691

High

788982

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.691

High

788995

CNN3
Calponin-3

1

5

High-throughput

0.691

High

338081

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

383671

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

441187

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.647

High

601835

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

616906

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

High-throughput

0.647

High

617085

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

20

High-throughput

0.647

High

788986

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.647

High

788988

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.647

High

788993

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.647

High

788994

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

788996

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

20

High-throughput

0.647

High

788997

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

20

High-throughput

0.647

High

789009

ARHGC
Rho guanine nucleotide exchange factor 12

1

16

Small-scale

0.647

High

789012

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

15

Small-scale

0.647

High

129232

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

Small-scale

0.621

High

433631

LYN
Tyrosine-protein kinase Lyn

1

19

Small-scale

0.618

High

548654

VAV
Proto-oncogene vav

1

20

Small-scale

0.618

High

616758

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.618

High

666032

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.618

High

789013

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.618

High

789017

SNX9
Sorting nexin-9

1

10

High-throughput

0.618

High

560468

PRLR
Prolactin receptor

1

20

Small-scale

0.561

High

789018

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.561

High

789014

TUTLB
Protein turtle homolog B

1

9

High-throughput

0.553

High

788983

ADAM8
Disintegrin and metalloproteinase domain-containing protein 8

1

20

Small-scale

0.536

High

789006

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

6

Small-scale

0.536

High

164810

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.536

High

727216

NU214
Nuclear pore complex protein Nup214

1

11

High-throughput

0.536

High

788977

MAP1B
Microtubule-associated protein 1B

1

8

High-throughput

0.536

High

789003

LTV1
Protein LTV1 homolog

1

1

High-throughput

0.536

High

789010

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

7

High-throughput

0.536

High

788976

WASP
Actin nucleation-promoting factor WAS

1

20

Small-scale

0.527

High

788981

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.513

High

789004

SORT
Sortilin

1

0

High-throughput

0.513

High

788978

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

12

Small-scale

0.501

High

788989

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

20

Small-scale

0.501

High

788990

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.501

High

789007

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

20

Small-scale

0.501

High

789015

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

788975

RBM34
RNA-binding protein 34

1

12

High-throughput

0.489

High

788987

TP53B
TP53-binding protein 1

1

6

High-throughput

0.489

High

788992

UBP2L
Ubiquitin-associated protein 2-like

1

8

High-throughput

0.489

High

789000

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

7

High-throughput

0.489

High

239072

CTND1
Catenin delta-1

1

18

High-throughput

0.479

High

657900

PEX2
Peroxisome biogenesis factor 2

1

3

High-throughput

0.479

High

722663

SPRE
Sepiapterin reductase

1

6

High-throughput

0.479

High

751520

GRP75
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

788979

PAXI
Paxillin

1

20

High-throughput

0.479

High

788984

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

1

Small-scale

0.479

High

788985

KMT2A
Histone-lysine N-methyltransferase 2A

1

10

High-throughput

0.479

High

788999

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

8

High-throughput

0.479

High

789001

MSI2H
RNA-binding protein Musashi homolog 2

1

12

High-throughput

0.479

High

789002

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

8

High-throughput

0.479

High

789011

LTOR3
Ragulator complex protein LAMTOR3

1

3

High-throughput

0.479

High

789016

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

6

High-throughput

0.479

High

789008

MED28
Mediator of RNA polymerase II transcription subunit 28

1

8

Small-scale

0.470

High

317086

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

3

High-throughput

0.437

High

426591

H10
Histone H1.0

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024