Protein: ISK7
Serine protease inhibitor Kazal-type 7 (Esophagus cancer-related gene 2 protein) (ECRG-2)

Gene: ISK7, SPINK7
Organism: Homo sapiens
Interactions: 19
UniProt ID: P58062

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0006954 - inflammatory response
GO:1900016 - negative regulation of cytokine production involved in inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

539791

IDE
Insulin-degrading enzyme

2

6

High-throughput

0.628

High

474974

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.602

High

365267

MT2
Metallothionein-2

2

2

Small-scale

0.592

High

885206

BIRC2
Baculoviral IAP repeat-containing protein 2

2

1

High-throughput

0.574

High

885209

ZER1
Protein zer-1 homolog

2

1

High-throughput

0.574

High

885210

ARMC8
Armadillo repeat-containing protein 8

2

1

High-throughput

0.574

High

531314

MT1G
Metallothionein-1G

2

1

Small-scale

0.550

High

885205

MT1H
Metallothionein-1H

2

2

Small-scale

0.550

High

885208

MAEA
E3 ubiquitin-protein transferase MAEA

1

1

High-throughput

0.489

High

885213

GID8
Glucose-induced degradation protein 8 homolog

1

1

High-throughput

0.489

High

885204

HBA
Hemoglobin subunit alpha

1

0

Small-scale

0.460

High

885212

LYPD1
Ly6/PLAUR domain-containing protein 1

2

0

High-throughput

0.328

High

885214

SMPX
Small muscular protein

2

0

High-throughput

0.328

High

173006

RT12
Small ribosomal subunit protein uS12m

2

0

Small-scale

0.314

High

560360

EPB42
Protein 4.2

2

0

Small-scale

0.314

High

885207

RABL6
Rab-like protein 6

2

0

Small-scale

0.314

High

885211

Q8IZW4
Esophagus cancer-related gene-2 interaction susceptibility protein

2

0

Small-scale

0.295

High

751556

GRP75
Stress-70 protein, mitochondrial

1

0

High-throughput

0.279

Low

364857

FRIL
Ferritin light chain

1

0

Small-scale

0.251

Low


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Last updated: 15 Jul 2024