Protein: SPHM
N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase)

Gene: SPHM, SGSH
Organism: Homo sapiens
Interactions: 34
UniProt ID: P51688

Gene Ontology (top 5):
GO:0005539 - glycosaminoglycan binding
GO:0005764 - lysosome
GO:0006027 - glycosaminoglycan catabolic process
GO:0008340 - determination of adult lifespan
GO:0008449 - N-acetylglucosamine-6-sulfatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

546599

ARSA
Arylsulfatase A

1

7

High-throughput

0.691

High

606866

IDS
Iduronate 2-sulfatase

1

7

High-throughput

0.691

High

849848

FBX6
F-box only protein 6

5

10

High-throughput

0.652

High

849834

NAAA
N-acylethanolamine-hydrolyzing acid amidase

2

6

High-throughput

0.611

High

849835

UPAR
Urokinase plasminogen activator surface receptor

3

4

High-throughput

0.609

High

849842

SUMF1
Formylglycine-generating enzyme

2

13

Small-scale

0.565

High

211354

PI15
Peptidase inhibitor 15

1

3

High-throughput

0.536

High

501850

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.536

High

514789

MPRI
Cation-independent mannose-6-phosphate receptor

1

6

High-throughput

0.536

High

532917

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.536

High

654183

CALX
Calnexin

1

8

High-throughput

0.536

High

849843

GGH
Gamma-glutamyl hydrolase

1

3

High-throughput

0.536

High

849850

DNJB9
DnaJ homolog subfamily B member 9

1

1

High-throughput

0.536

High

849837

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.513

High

849845

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.513

High

301078

FBX21
F-box only protein 21

1

6

High-throughput

0.489

High

319524

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.489

High

561293

CRIS2
Cysteine-rich secretory protein 2

1

3

High-throughput

0.489

High

849831

MFAP4
Microfibril-associated glycoprotein 4

1

4

High-throughput

0.489

High

849832

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.489

High

849833

IL5RA
Interleukin-5 receptor subunit alpha

1

4

High-throughput

0.489

High

849847

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.489

High

849849

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.489

High

849851

FBX2
F-box only protein 2

1

10

High-throughput

0.489

High

849840

TMM25
Transmembrane protein 25

1

2

High-throughput

0.479

High

849841

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

13

Small-scale

0.479

High

849846

SIAE
Sialate O-acetylesterase

1

3

High-throughput

0.479

High

174735

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.457

High

517140

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

205193

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.437

High

849838

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

849839

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

849836

INSL4
Early placenta insulin-like peptide

1

0

High-throughput

0.279

Low

849844

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024