HitPredict

Interactor 1: MAML2 (Q8IZL2)
Mastermind-like protein 2 (Mam-2)
Gene: MAML2

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15961999
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1156 Hs			1 2442
+	Hs
		998874 MAML2_HUMAN (1-1156): 6.1e-121: 403: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		1267676 MAML1_HUMAN (33-989): 3.38e-37: 154: 17.96		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		846837 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		998929 MAML1_HUMAN (33-989): 3.38e-37: 154: 17.96		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		554303 MUC1_HUMAN (478-1114): 1.38e-33: 142: 9.59		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		846760 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Dm
		115984 BRM_DROME (454-805): 5.49e-13: 76.1: 10.67		M9PH39_DROME (480-2357): 0: 829: 35.44
+	Hs
		1067006 NIPBL_HUMAN (50-829): 6.31e-78: 285: 11.21		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		846897 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		631379 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		846778 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		1017367 BPTF_HUMAN (154-1045): 1.38e-25: 117: 8.60		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		1017300 BPTF_HUMAN (154-1045): 1.38e-25: 117: 8.60		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631413 BPTF_HUMAN (154-1045): 1.38e-25: 117: 8.60		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		554259 MUC1_HUMAN (478-1114): 1.38e-33: 142: 9.59		MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02
+	Hs
		1199170 MAML1_HUMAN (33-989): 3.38e-37: 154: 17.96		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Dm
		113976 M9PB30_DROME (445-1118): 1.65e-27: 124: 11.83		M9PB30_DROME (244-1120): 3.23e-21: 104: 9.85
+	Hs
		846812 SMCA2_HUMAN (359-805): 3.86e-33: 141: 14.08		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Mm
		1351630 PCLO_MOUSE (424-1139): 1.13e-16: 88.2: 11.58		PCLO_MOUSE (1831-2420): 5.14e-13: 77.5: 10.91
+	Mm
		101535 SMCA2_MOUSE (368-805): 3.92e-11: 69.8: 14.29		F8VQD1_MOUSE (1040-1275): 7.54e-13: 76.7: 14.41