HitPredict

Interactor 1: ACSL4 (O60488)
Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4)
Gene: ACSL4

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 711 Hs			1 196
+	Hs
		234803 ACSL4_HUMAN (1-711): 0: 759: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		234801 ACSL4_HUMAN (1-711): 0: 759: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		316622 ACSL3_HUMAN (1-711): 0: 724: 65.54		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		316614 ACSL3_HUMAN (1-711): 0: 724: 65.54		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		316568 ACSL3_HUMAN (1-711): 0: 724: 65.54		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		316555 ACSL3_HUMAN (1-711): 0: 724: 65.54		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		316626 ACSL3_HUMAN (1-711): 0: 724: 65.54		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		316610 ACSL3_HUMAN (1-711): 0: 724: 65.54		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		316611 ACSL3_HUMAN (1-711): 0: 724: 65.54		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		120262 ACSL3_HUMAN (1-711): 0: 724: 65.54		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Sc
		419717 ACS2_YEAST (85-707): 4.38e-144: 438: 15.45		RHO1_YEAST (3-186): 1.7e-88: 260: 67.39