HitPredict

Interactor 1: SNX3 (O60493)
Sorting nexin-3 (Protein SDP3)
Gene: SNX3

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031901 - early endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 162 Hs			1 216
+	Hs
		234903 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		234937 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		240367 SNX2_HUMAN (2-162): 3.18e-46: 159: 24.24		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		240349 SNX2_HUMAN (2-162): 3.18e-46: 159: 24.24		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		240376 SNX2_HUMAN (2-162): 3.18e-46: 159: 24.24		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		592238 SNX1_HUMAN (3-162): 2.03e-43: 151: 21.95		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		914056 SNX1_HUMAN (3-162): 2.03e-43: 151: 21.95		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		592308 SNX30_HUMAN (17-153): 7.44e-38: 135: 29.71		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		844798 SNX6_HUMAN (1-148): 1.05e-30: 116: 19.43		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		592580 SNX6_HUMAN (1-148): 1.05e-30: 116: 19.43		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		592612 SNX5_HUMAN (3-149): 4.75e-30: 114: 20.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		914459 SNX6_HUMAN (1-148): 1.05e-30: 116: 19.43		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		914493 SNX5_HUMAN (3-149): 4.75e-30: 114: 20.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		307890 SNX4_HUMAN (28-160): 1.38e-29: 113: 26.76		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Sc
		731259 SNX3_YEAST (19-150): 3.02e-35: 122: 42.66		YPT53_YEAST (23-200): 2.29e-55: 177: 51.09