Interactor 1: CUBN (O60494)
Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Interactor 2: IF (P27352)
Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF)
Gene: CBLIF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.90 0.770

The method score is based on:

Property Details
Experiments 9572993, 20237569
Identification Methods pull down, x-ray crystallography, ion exchange chromatography, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cobalamin_bind~CUB
Common GO terms GO:0005768 - endosome
GO:0015889 - cobalamin transport
GO:0016324 - apical plasma membrane
GO:0031419 - cobalamin binding
GO:0043202 - lysosomal lumen
Homologous interactions 0

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Last updated: 15 Jul 2024