Interactor 1: DOK2 (O60496)
Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2))
Gene: DOK2

Interactor 2: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 10822173
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005829 - cytosol
GO:0043410 - positive regulation of MAPK cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 412
Hs

1 583
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024