Interactor 1: DOK2 (O60496)
Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2))
Gene: DOK2
Interactor 2: DOK3 (Q7L591)
Docking protein 3 (Downstream of tyrosine kinase 3)
Gene: DOK3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 1.00 | 0.767 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25814554, unassigned1126 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IRS~IRS |
| Common GO terms | GO:0005737 - cytoplasm GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway GO:0007265 - Ras protein signal transduction GO:0043410 - positive regulation of MAPK cascade |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
