HitPredict

Interactor 1: STX10 (O60499)
Syntaxin-10 (Syn10)
Gene: STX10

Interactor 2: STX3 (Q13277)
Syntaxin-3
Gene: STX3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~SNARE, SNARE~Syntaxin
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport GO:0012505 - endomembrane system GO:0031201 - SNARE complex and 1 others more... GO:0048278 - vesicle docking
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 249 Hs			1 289
+	Hs
		235176 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX1A_HUMAN (1-286): 4.49e-75: 233: 62.98
+	Hs
		212746 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX2_HUMAN (1-287): 3.91e-77: 238: 63.45
+	Hs
		212845 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX1A_HUMAN (1-286): 4.49e-75: 233: 62.98
+	Hs
		235169 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX4_HUMAN (1-286): 8.41e-62: 199: 39.32
+	Hs
		212822 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX3_HUMAN (1-289): 6.42e-71: 222: 100.00
+	Hs
		235131 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX11_HUMAN (1-273): 2.64e-52: 174: 29.37
+	Hs
		212813 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX4_HUMAN (1-286): 8.41e-62: 199: 39.32
+	Hs
		152120 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX16_HUMAN (39-263): 2.72e-50: 170: 20.96
+	Hs
		235191 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX12_HUMAN (28-270): 8.2e-51: 170: 25.91
+	At
		1276971 SYP61_ARATH (2-248): 9.59e-63: 198: 21.20		SYP42_ARATH (37-283): 2.41e-55: 183: 20.57
+	Hs
		178319 STX10_HUMAN (1-233): 1.52e-69: 215: 100.00		STX7_HUMAN (37-284): 2.99e-48: 163: 25.79
+	Mm
		1206470 STX6_MOUSE (1-233): 6.54e-61: 193: 61.93		Q8BH40_MOUSE (37-287): 1.86e-56: 184: 26.67
+	At
		1276972 SYP61_ARATH (2-248): 9.59e-63: 198: 21.20		SY121_ARATH (28-265): 1.04e-53: 179: 22.40
+	At
		249582 SYP61_ARATH (2-248): 9.59e-63: 198: 21.20		SYP41_ARATH (40-283): 1.66e-51: 173: 18.33
+	At
		1276970 SYP61_ARATH (2-248): 9.59e-63: 198: 21.20		SYP43_ARATH (34-283): 2.38e-50: 170: 17.90
+	Hs
		212692 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX11_HUMAN (1-273): 2.64e-52: 174: 29.37
+	Hs
		152119 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX16_HUMAN (39-263): 2.72e-50: 170: 20.96
+	Hs
		212911 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX12_HUMAN (28-270): 8.2e-51: 170: 25.91
+	Hs
		178314 STX6_HUMAN (1-233): 6.56e-59: 188: 61.09		STX7_HUMAN (37-284): 2.99e-48: 163: 25.79
+	At
		955691 SYP71_ARATH (1-247): 9.28e-48: 160: 16.19		SYP22_ARATH (40-271): 4.19e-47: 160: 19.67