HitPredict

Interactor 1: B7ZLY3 (B7ZLY3)
LTBP1 protein
Gene: LTBP1

Interactor 2: CAC1A (O00555)
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)
Gene: CACNA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	21078624
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1353 Hs			1 2506
+	Hs
		132298 NOTC1_HUMAN (546-1349): 8.19e-69: 258: 14.96		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132314 LTBP1_HUMAN (10-787): 2.44e-29: 129: 14.32		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132274 MEGF6_HUMAN (2-538): 9.16e-25: 114: 10.12		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132361 JAG2_HUMAN (9-289): 3.86e-18: 92.8: 11.72		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132308 FBLN3_HUMAN (699-952): 7.12e-18: 90.5: 31.70		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132280 FBLN4_HUMAN (563-721): 2.23e-16: 85.5: 35.40		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		126309 MATN2_HUMAN (1172-1353): 9.8e-15: 81.6: 17.20		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132331 LTBP4_HUMAN (913-1352): 2.02e-13: 77.8: 14.70		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132356 LTBP3_HUMAN (14-519): 2.5e-12: 74: 11.11		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		132290 FBLN1_HUMAN (848-1138): 5.87e-12: 72.4: 27.58		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		82701 B9EG76_HUMAN (897-1349): 2.07e-10: 67.8: 12.90		CAC1A_HUMAN (1-2506): 0: 1897: 100.00
+	Hs
		1016946 FBLN3_HUMAN (699-952): 7.12e-18: 90.5: 31.70		CAC1C_HUMAN (1129-1934): 1.84e-95: 348: 18.82
+	Hs
		1047292 CELR3_HUMAN (900-1005): 6.03e-09: 63.2: 16.98		CAC1C_HUMAN (1129-1934): 1.84e-95: 348: 18.82
+	Dm
		422755 NOTCH_DROME (10-429): 2.25e-23: 110: 10.33		CAC1D_DROME (1194-1544): 1.16e-38: 162: 22.79