HitPredict

Interactor 1: B7ZMA4 (B7ZMA4)
LOC553158 protein
Gene: LOC553158

Interactor 2: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	32296183, 33961781
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 368
+	Hs
		81935 B7ZMA4_HUMAN (1-486): 1.18e-171: 493: 100.00		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		69703 B1AHC3_HUMAN (1-486): 6.88e-168: 486: 95.27		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		69705 B1AHC3_HUMAN (1-486): 6.88e-168: 486: 95.27		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		81934 B7ZMA4_HUMAN (1-486): 1.18e-171: 493: 100.00		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		69704 B1AHC3_HUMAN (1-486): 6.88e-168: 486: 95.27		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		1224597 Q8IZM6_HUMAN (37-486): 5.73e-148: 431: 94.67		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		952918 RHG08_HUMAN (37-486): 1.52e-142: 418: 88.77		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		952920 RHG08_HUMAN (37-486): 1.52e-142: 418: 88.77		SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30
+	Hs
		952919 RHG08_HUMAN (37-486): 1.52e-142: 418: 88.77		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		993058 RHG01_HUMAN (44-440): 4.7e-120: 360: 54.27		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		81928 B7ZMA4_HUMAN (1-486): 1.18e-171: 493: 100.00		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		69699 B1AHC3_HUMAN (1-486): 6.88e-168: 486: 95.27		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		200231 SRGP3_HUMAN (175-484): 6.24e-65: 228: 22.12		SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00
+	Hs
		200232 SRGP3_HUMAN (175-484): 6.24e-65: 228: 22.12		SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75
+	Hs
		1052250 RHG24_HUMAN (187-477): 6.71e-71: 241: 22.74		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		1052327 RHG35_HUMAN (144-461): 1.34e-66: 234: 20.12		SRC8_HUMAN (35-362): 1.55e-37: 143: 12.16
+	Hs
		924893 RHG35_HUMAN (144-461): 1.34e-66: 234: 20.12		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		200212 SRGP3_HUMAN (175-484): 6.24e-65: 228: 22.12		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924608 Q1RLN5_HUMAN (183-435): 2.08e-64: 224: 21.88		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38
+	Hs
		924686 RHG12_HUMAN (183-435): 4.07e-64: 224: 21.88		GRB2_HUMAN (311-367): 1.59e-11: 65.2: 41.38