Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: UFD1 (Q92890)
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1)
Gene: UFD1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 26712280, 26389662, 28320958, 27684549, 31477623, 33961781, 19275885, 15371428, 24248593, 26549226, 27226613, 27913212, 29599191, 29540532, 28443643, 18199748, 34739333, 35271311, 17872946, 35349166 and 7 others

more...

Identification Methods pull down, affinity chromatography technology, x-ray crystallography, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0030970 - retrograde protein transport, ER to cytosol
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 806
Hs

1 307
+ Rn
+ Mm
+ Xl
+ Dm
+ Sc
+ Ce
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024