Physical protein-protein interactions with reliability scores

Search protein-protein interactions (v15 - 11Aug2025)
Enter a name, UniProt ID, Entrez ID or Ensembl ID for a protein, eg. BRCA1, P61077

Protein-protein interactions from IntAct, BioGRID, MINT, DIP, MatrixDB, InnateDB are combined, annotated and scored. The reliability score is calculated based on the experimental details of each interaction and the sequence, structure and functional annotations of the interacting proteins.


HitPredict version 15 (11Aug2025) is searchable:

  • 1,492,106 experimentally identified physical protein-protein interactions
  • 113,798 proteins
  • 124 species

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HitPredict update version 16 (2Jul2026) is available for licensing:

  • 1,558,166 experimentally identified physical protein-protein interactions
  • 106,079 proteins
  • 112 species

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Service provided by Combinatics, Japan

Last updated: 11Aug2025