HitPredict - High confidence protein-protein interactions

Protein: DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (dDOT1L) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Protein grappa)

Gene: DOT1L, gpp
Organism: Drosophila melanogaster
Interactions: 7
UniProt ID: Q8INR6

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0031151 - histone H3K79 methyltransferase activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1213667	Q9VH81 protein-serine/threonine phosphatase	1	2	High-throughput	0.484	High
1213668	Q9VNZ7 LD44094p	1	4	High-throughput	0.464	High
1213669	EXOC5 Exocyst complex component 5	1	0	High-throughput	0.282	High
1213666	CSN4 COP9 signalosome complex subunit 4	1	0	High-throughput	0.265	Low
1213671	Q9XZS4 EG:22E5.12 protein	1	0	High-throughput	0.265	Low
1213670	4EBP Eukaryotic translation initiation factor 4E-binding protein	1	0	High-throughput	0.253	Low
1213665	NRX4 Neurexin-4	1	0	High-throughput	0.232	Low

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Last updated: 15 Jul 2024