Protein: DESI1
Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (Polyubiquitinated substrate transporter) (POST) (S-depalmitoylase DESI1)

Gene: DESI1
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q6ICB0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0006611 - protein export from nucleus
GO:0008474 - palmitoyl-(protein) hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1152462

UBQL2
Ubiquilin-2

4

6

Small-scale

0.684

High

475917

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

4

Small-scale

0.658

High

1152463

UBQL1
Ubiquilin-1

3

6

Small-scale

0.653

High

475061

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

4

High-throughput

0.606

High

924035

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

4

High-throughput

0.606

High

924325

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

4

High-throughput

0.606

High

1152449

UBQLN
Ubiquilin-like protein

2

6

High-throughput

0.606

High

1152458

CDIP1
Cell death-inducing p53-target protein 1

2

0

High-throughput

0.589

High

941041

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.580

High

952931

PRR5
Proline-rich protein 5

2

0

High-throughput

0.580

High

1028317

NDK3
Nucleoside diphosphate kinase 3

2

0

High-throughput

0.580

High

1065112

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

1152455

UHRF2
E3 ubiquitin-protein ligase UHRF2

2

0

High-throughput

0.580

High

1152457

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.580

High

1152448

ZBT46
Zinc finger and BTB domain-containing protein 46

1

1

Small-scale

0.561

High

271965

CTAG2
Cancer/testis antigen 2

2

1

High-throughput

0.553

High

942521

CTG1B
Cancer/testis antigen 1

2

1

High-throughput

0.553

High

349403

RASH
GTPase HRas

1

3

High-throughput

0.536

High

1151064

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

820325

SPB4
Serpin B4

1

0

High-throughput

0.513

High

1038465

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.513

High

838047

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

162870

XPO1
Exportin-1

1

0

Small-scale

0.480

High

121796

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

1

Small-scale

0.479

High

122040

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

Small-scale

0.479

High

156312

PSA7
Proteasome subunit alpha type-7

1

5

Small-scale

0.479

High

572995

PRS6A
26S proteasome regulatory subunit 6A

1

3

Small-scale

0.479

High

594564

PSB1
Proteasome subunit beta type-1

1

6

Small-scale

0.479

High

637456

PSA1
Proteasome subunit alpha type-1

1

5

Small-scale

0.479

High

637705

PSA2
Proteasome subunit alpha type-2

1

6

Small-scale

0.479

High

638151

PSA4
Proteasome subunit alpha type-4

1

5

Small-scale

0.479

High

656253

PSA5
Proteasome subunit alpha type-5

1

5

Small-scale

0.479

High

656734

PSB5
Proteasome subunit beta type-5

1

4

Small-scale

0.479

High

730290

PRS7
26S proteasome regulatory subunit 7

1

2

Small-scale

0.479

High

798698

PRS6B
26S proteasome regulatory subunit 6B

1

2

Small-scale

0.479

High

803582

BAG6
Large proline-rich protein BAG6

1

5

Small-scale

0.479

High

832011

PSB3
Proteasome subunit beta type-3

1

4

Small-scale

0.479

High

874122

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

Small-scale

0.479

High

893693

PSA6
Proteasome subunit alpha type-6

1

6

Small-scale

0.479

High

906860

PRS4
26S proteasome regulatory subunit 4

1

2

Small-scale

0.479

High

907067

PRS8
26S proteasome regulatory subunit 8

1

3

Small-scale

0.479

High

1152452

PSMA8
Proteasome subunit alpha-type 8

1

6

Small-scale

0.479

High

1152456

PSB7
Proteasome subunit beta type-7

1

2

Small-scale

0.479

High

1152459

UBQL4
Ubiquilin-4

1

7

Small-scale

0.479

High

46255

A0A1U9X8X8
Corneodesmosin

1

1

High-throughput

0.470

High

1117579

Q4KN05
KLRF1 protein

1

1

High-throughput

0.470

High

632304

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

819818

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

Small-scale

0.458

High

874638

BI1
Bax inhibitor 1

1

0

Small-scale

0.458

High

903989

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.458

High

1074533

CDSN
Corneodesmosin

1

1

High-throughput

0.439

High

1152460

KLRF1
Killer cell lectin-like receptor subfamily F member 1

1

1

High-throughput

0.439

High

670609

ERP29
Endoplasmic reticulum resident protein 29

2

0

High-throughput

0.316

High

713733

EVI2B
Protein EVI2B

2

0

High-throughput

0.316

High

886930

T2R41
Taste receptor type 2 member 41

2

0

High-throughput

0.316

High

1107807

SMI21
Small integral membrane protein 21

2

0

High-throughput

0.316

High

1152450

SHSA5
Protein shisa-5

2

0

High-throughput

0.316

High

1152451

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.316

High

1152453

AGR3
Anterior gradient protein 3

2

0

High-throughput

0.316

High

1152454

SHSA4
Protein shisa-4

2

0

High-throughput

0.316

High

1152461

ABI3
ABI gene family member 3

2

0

High-throughput

0.316

High

1129253

SPXN5
Sperm protein associated with the nucleus on the X chromosome N5

1

0

High-throughput

0.279

Low

1152447

PLPR4
Phospholipid phosphatase-related protein type 4

1

0

High-throughput

0.279

Low

601116

FGF7
Fibroblast growth factor 7

1

0

High-throughput

0.251

Low

1129201

CD158
Coiled-coil domain-containing protein 158

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024