Protein: EXOC8
Exocyst complex component 8 (Exocyst complex 84 kDa subunit)

Gene: EXOC8
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q8IYI6

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223250

EXOC2
Exocyst complex component 2

5

2

Small-scale

0.930

High

506460

RALB
Ras-related protein Ral-B

7

4

Small-scale

0.749

High

1223246

EXOC4
Exocyst complex component 4

4

2

Small-scale

0.704

High

130080

EXOC5
Exocyst complex component 5

4

1

High-throughput

0.699

High

1223283

EXOC7
Exocyst complex component 7

4

2

High-throughput

0.699

High

1223279

IKZF3
Zinc finger protein Aiolos

4

1

High-throughput

0.698

High

1223236

EXOC6
Exocyst complex component 6

3

3

High-throughput

0.675

High

1223285

EXC6B
Exocyst complex component 6B

3

3

High-throughput

0.675

High

444420

K1C19
Keratin, type I cytoskeletal 19

3

4

High-throughput

0.667

High

237988

EXOC3
Exocyst complex component 3

3

1

High-throughput

0.667

High

1223272

EXOC1
Exocyst complex component 1

3

0

High-throughput

0.646

High

1068797

PCM1
Pericentriolar material 1 protein

3

0

High-throughput

0.639

High

1223280

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

3

0

High-throughput

0.639

High

600611

EPHA1
Ephrin type-A receptor 1

2

1

High-throughput

0.628

High

1223261

EHD4
EH domain-containing protein 4

2

1

High-throughput

0.628

High

1223265

EHD1
EH domain-containing protein 1

2

1

High-throughput

0.628

High

1223269

MBIP1
MAP3K12-binding inhibitory protein 1

2

0

High-throughput

0.623

High

280813

KRT36
Keratin, type I cuticular Ha6

2

5

High-throughput

0.615

High

280643

KRT34
Keratin, type I cuticular Ha4

2

5

High-throughput

0.606

High

536918

TRI27
Zinc finger protein RFP

2

1

High-throughput

0.606

High

585009

RO52
E3 ubiquitin-protein ligase TRIM21

2

1

High-throughput

0.606

High

965446

K22O
Keratin, type II cytoskeletal 2 oral

2

1

High-throughput

0.606

High

161546

S27A2
Long-chain fatty acid transport protein 2

2

0

High-throughput

0.602

High

655186

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

1025312

LIPA1
Liprin-alpha-1

2

0

High-throughput

0.602

High

1071608

LRC41
Leucine-rich repeat-containing protein 41

2

0

High-throughput

0.602

High

1223233

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.602

High

1223273

OCAD1
OCIA domain-containing protein 1

2

0

High-throughput

0.602

High

1223286

3BP1
SH3 domain-binding protein 1

2

0

High-throughput

0.602

High

1054161

BECN1
Beclin-1

2

0

Small-scale

0.595

High

246366

SCN2B
Sodium channel subunit beta-2

2

0

High-throughput

0.585

High

1220509

TARG1
Trafficking regulator of GLUT4 1

2

0

High-throughput

0.585

High

1223282

CAH14
Carbonic anhydrase 14

2

0

High-throughput

0.585

High

155032

NDC80
Kinetochore protein NDC80 homolog

2

0

High-throughput

0.580

High

532316

ZNF35
Zinc finger protein 35

2

0

High-throughput

0.580

High

595833

CAN3
Calpain-3

2

0

High-throughput

0.580

High

664104

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.580

High

995034

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.580

High

1026312

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

2

0

High-throughput

0.580

High

1156459

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.580

High

1163352

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.580

High

1168340

SCAR5
Scavenger receptor class A member 5

2

0

High-throughput

0.580

High

1223240

CCHCR
Coiled-coil alpha-helical rod protein 1

2

0

High-throughput

0.580

High

1223253

SYT17
Synaptotagmin-17

2

0

High-throughput

0.580

High

1223256

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

1223266

MARH7
E3 ubiquitin-protein ligase MARCHF7

2

0

High-throughput

0.580

High

1223267

VP37B
Vacuolar protein sorting-associated protein 37B

2

0

High-throughput

0.580

High

1223268

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

1223270

F217B
Protein FAM217B

2

0

High-throughput

0.580

High

1223275

STMN3
Stathmin-3

2

0

High-throughput

0.580

High

1223284

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.580

High

1223287

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.580

High

66295

WASH1
WASH complex subunit 1

2

0

Small-scale

0.575

High

1071265

K1H1
Keratin, type I cuticular Ha1

1

5

High-throughput

0.573

High

338678

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.559

High

551198

ITF2
Transcription factor 4

2

1

High-throughput

0.553

High

1049084

TRI14
Tripartite motif-containing protein 14

2

2

High-throughput

0.553

High

1188218

NUP54
Nucleoporin p54

2

1

High-throughput

0.553

High

1223234

ZSCA4
Zinc finger and SCAN domain-containing protein 4

2

2

High-throughput

0.553

High

1223251

HTF4
Transcription factor 12

2

1

High-throughput

0.553

High

1223259

TRI54
Tripartite motif-containing protein 54

2

3

High-throughput

0.553

High

1223276

TFP11
Tuftelin-interacting protein 11

2

1

High-throughput

0.553

High

408865

K1C18
Keratin, type I cytoskeletal 18

1

5

High-throughput

0.541

High

580062

K1C15
Keratin, type I cytoskeletal 15

1

4

High-throughput

0.541

High

729034

K1C20
Keratin, type I cytoskeletal 20

1

6

High-throughput

0.541

High

262287

ULK1
Serine/threonine-protein kinase ULK1

1

0

Small-scale

0.537

High

1127559

EFHC2
EF-hand domain-containing family member C2

1

0

High-throughput

0.536

High

1223238

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.536

High

160087

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

High-throughput

0.518

High

362242

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

529390

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

824722

NPY2R
Neuropeptide Y receptor type 2

1

0

High-throughput

0.513

High

856415

EFNA4
Ephrin-A4

1

0

High-throughput

0.513

High

927286

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.513

High

1223230

PALS1
Protein PALS1

1

0

High-throughput

0.513

High

1223254

TMM43
Transmembrane protein 43

1

0

High-throughput

0.513

High

1223260

DERL2
Derlin-2

1

0

High-throughput

0.513

High

1223277

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

254920

CPNE3
Copine-3

1

0

High-throughput

0.493

High

805543

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

0

High-throughput

0.493

High

806920

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.493

High

506399

RALA
Ras-related protein Ral-A

1

3

Small-scale

0.481

High

1074545

CDSN
Corneodesmosin

1

1

High-throughput

0.481

High

1223262

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

1

High-throughput

0.481

High

46258

A0A1U9X8X8
Corneodesmosin

1

1

High-throughput

0.470

High

1151485

Q6GMQ7
Vacuolar protein sorting-associated protein 16 homolog

1

1

High-throughput

0.470

High

299118

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.460

High

313179

RPGF3
Rap guanine nucleotide exchange factor 3

1

0

High-throughput

0.460

High

385145

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

894764

RAB8A
Ras-related protein Rab-8A

1

0

High-throughput

0.458

High

1035495

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1041996

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1165742

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1166151

OLFM4
Olfactomedin-4

1

0

High-throughput

0.458

High

1169272

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

1223235

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

0

Small-scale

0.458

High

1223243

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

0

Small-scale

0.458

High

1223264

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1223274

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1223278

SEPT9
Septin-9

1

0

Small-scale

0.458

High

941140

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1170743

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1223232

USBP1
Harmonin-binding protein USHBP1

3

0

High-throughput

0.353

High

1021922

SEC20
Vesicle transport protein SEC20

2

0

High-throughput

0.328

High

130163

ELL2
RNA polymerase II elongation factor ELL2

2

0

High-throughput

0.316

High

474624

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1032326

ZN177
Zinc finger protein 177

2

0

High-throughput

0.316

High

1077766

NAB2
NGFI-A-binding protein 2

2

0

High-throughput

0.316

High

1082486

SNPC1
snRNA-activating protein complex subunit 1

2

0

High-throughput

0.316

High

1103221

C19L2
CWF19-like protein 2

2

0

High-throughput

0.316

High

1125495

ZN628
Zinc finger protein 628

2

0

High-throughput

0.316

High

1127050

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

1133623

SKT
Sickle tail protein homolog

2

0

High-throughput

0.316

High

1149584

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

2

0

High-throughput

0.316

High

1152426

GRAM4
GRAM domain-containing protein 4

2

0

High-throughput

0.316

High

1174055

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

1222737

IHO1
Interactor of HORMAD1 protein 1

2

0

High-throughput

0.316

High

1223228

SYCE1
Synaptonemal complex central element protein 1

2

0

High-throughput

0.316

High

1223229

AN36B
Ankyrin repeat domain-containing protein 36B

2

0

High-throughput

0.316

High

1223239

MIPO1
Mirror-image polydactyly gene 1 protein

2

0

High-throughput

0.316

High

1223241

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

1223242

MB3L1
Methyl-CpG-binding domain protein 3-like 1

2

0

High-throughput

0.316

High

1223245

ZN566
Zinc finger protein 566

2

0

High-throughput

0.316

High

1223247

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.316

High

1223248

BORC6
BLOC-1-related complex subunit 6

2

0

High-throughput

0.316

High

1223249

ZC21A
Zinc finger C2HC domain-containing protein 1A

2

0

High-throughput

0.316

High

1223252

UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2

2

0

High-throughput

0.316

High

1223255

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

1223257

BEX2
Protein BEX2

2

0

High-throughput

0.316

High

1223258

PBX4
Pre-B-cell leukemia transcription factor 4

2

0

High-throughput

0.316

High

1223263

GO45
Golgin-45

2

0

High-throughput

0.316

High

1223271

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.316

High

1223281

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

0

High-throughput

0.316

High

1223227

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.299

High

266383

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.282

High

1079243

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.282

High

872914

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

948095

RT15
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.269

Low

1223231

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

1223237

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.251

Low

1026473

RFA4
Replication protein A 30 kDa subunit

1

0

High-throughput

0.249

Low

1108789

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

0

High-throughput

0.249

Low

1223244

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024