Protein: ARPC3
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)

Gene: ARPC3
Organism: Homo sapiens
Interactions: 166
UniProt ID: O15145

Gene Ontology (top 5):
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

169062

ARP2
Actin-related protein 2

9

5

High-throughput

0.973

High

169061

ARP3
Actin-related protein 3

9

6

Small-scale

0.969

High

169141

ARP3B
Actin-related protein 3B

7

6

High-throughput

0.966

High

168997

ARPC5
Actin-related protein 2/3 complex subunit 5

7

2

Small-scale

0.750

High

168682

ARC1B
Actin-related protein 2/3 complex subunit 1B

7

4

Small-scale

0.749

High

168851

ARPC2
Actin-related protein 2/3 complex subunit 2

8

2

Small-scale

0.749

High

169058

ARPC4
Actin-related protein 2/3 complex subunit 4

7

3

Small-scale

0.749

High

169118

ARC1A
Actin-related protein 2/3 complex subunit 1A

6

4

Small-scale

0.738

High

169127

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

6

2

Small-scale

0.735

High

169059

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.691

High

169069

ACTG
Actin, cytoplasmic 2

1

2

High-throughput

0.691

High

126882

WASL
Actin nucleation-promoting factor WASL

3

4

High-throughput

0.675

High

169109

DOCK8
Dedicator of cytokinesis protein 8

3

1

High-throughput

0.667

High

169123

DOCK7
Dedicator of cytokinesis protein 7

3

1

High-throughput

0.667

High

169044

WASP
Actin nucleation-promoting factor WAS

3

5

Small-scale

0.661

High

168998

HXA3
Homeobox protein Hox-A3

3

0

High-throughput

0.646

High

169018

GALT
Galactose-1-phosphate uridylyltransferase

3

0

High-throughput

0.638

High

169135

ANLN
Anillin

3

0

High-throughput

0.628

High

169070

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.618

High

169072

GOGA2
Golgin subfamily A member 2

3

2

High-throughput

0.616

High

169079

SRC8
Src substrate cortactin

2

1

Small-scale

0.611

High

169094

DUS29
Dual specificity phosphatase 29

2

1

High-throughput

0.606

High

169133

ZN576
Zinc finger protein 576

2

1

High-throughput

0.606

High

169082

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

1

High-throughput

0.586

High

58207

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

2

0

High-throughput

0.580

High

169008

LATS1
Serine/threonine-protein kinase LATS1

2

0

High-throughput

0.580

High

169028

PO2F1
POU domain, class 2, transcription factor 1

2

0

High-throughput

0.580

High

169031

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.576

High

169015

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

169046

CCR10
C-C chemokine receptor type 10

2

1

High-throughput

0.553

High

169051

NRIP1
Nuclear receptor-interacting protein 1

1

0

High-throughput

0.549

High

169005

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

169045

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

1

High-throughput

0.541

High

117517

MYO1C
Unconventional myosin-Ic

1

4

High-throughput

0.536

High

169039

1433B
14-3-3 protein beta/alpha

1

3

High-throughput

0.536

High

169048

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.536

High

169068

1433Z
14-3-3 protein zeta/delta

1

3

High-throughput

0.536

High

169071

CALD1
Caldesmon

1

4

High-throughput

0.536

High

169098

BCOR
BCL-6 corepressor

1

1

High-throughput

0.536

High

169102

PIM3
Serine/threonine-protein kinase pim-3

1

1

High-throughput

0.536

High

169116

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.536

High

169122

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.536

High

169047

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.518

High

169057

LEG4
Galectin-4

1

0

High-throughput

0.518

High

169124

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

0

High-throughput

0.518

High

169126

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.518

High

169017

CATB
Cathepsin B

1

2

High-throughput

0.515

High

169148

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.515

High

168999

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

0

High-throughput

0.513

High

169013

FINC
Fibronectin

1

0

High-throughput

0.513

High

169033

FLNA
Filamin-A

1

0

High-throughput

0.513

High

169035

CXCR2
C-X-C chemokine receptor type 2

1

0

Small-scale

0.513

High

169042

MYH9
Myosin-9

1

0

High-throughput

0.513

High

169043

MNDA
Myeloid cell nuclear differentiation antigen

1

0

High-throughput

0.513

High

169049

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

169050

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

169055

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.513

High

169065

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

169078

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

169085

DREB
Drebrin

1

0

High-throughput

0.513

High

169090

CL16A
Protein CLEC16A

1

0

High-throughput

0.513

High

169106

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

169121

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

169136

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.513

High

169137

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.513

High

169142

STK26
Serine/threonine-protein kinase 26

1

0

High-throughput

0.513

High

169147

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

169087

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.508

High

169037

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

120211

RHOD
Rho-related GTP-binding protein RhoD

1

1

High-throughput

0.479

High

166641

CE290
Centrosomal protein of 290 kDa

1

2

High-throughput

0.479

High

169006

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.479

High

169007

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

169016

CATL1
Procathepsin L

1

1

High-throughput

0.479

High

169027

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

169029

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

169030

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

169054

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.479

High

169074

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

169075

DUS8
Dual specificity protein phosphatase 8

1

1

High-throughput

0.479

High

169089

DUS6
Dual specificity protein phosphatase 6

1

2

High-throughput

0.479

High

169110

BICD2
Protein bicaudal D homolog 2

1

3

High-throughput

0.479

High

169117

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

169119

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

169131

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

169146

TES
Testin

1

1

High-throughput

0.479

High

169114

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.470

High

169066

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

Small-scale

0.460

High

148144

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

155202

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

162202

XPO1
Exportin-1

1

0

High-throughput

0.458

High

168996

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.458

High

169001

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

169003

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

169009

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

169011

FOS
Protein c-Fos

1

0

High-throughput

0.458

High

169012

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

169014

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

169019

FURIN
Furin

1

0

High-throughput

0.458

High

169023

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.458

High

169025

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

169032

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

169038

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

169041

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

169053

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.458

High

169056

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

169060

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.458

High

169063

UFM1
Ubiquitin-fold modifier 1

1

0

High-throughput

0.458

High

169064

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

169073

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

169076

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

169081

CUL7
Cullin-7

1

0

High-throughput

0.458

High

169083

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

169084

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

169086

FSCN1
Fascin

1

0

High-throughput

0.458

High

169088

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

169096

ANO7
Anoctamin-7

1

0

Small-scale

0.458

High

169097

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

Small-scale

0.458

High

169111

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

169113

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

169115

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

169128

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

169130

SIK2
Serine/threonine-protein kinase SIK2

1

0

Small-scale

0.458

High

169134

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

169138

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

169144

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.458

High

169145

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

169095

Q6IBM8
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.457

High

46279

A0A1W2PNV4
Actin-related protein 2/3 complex subunit 1A

1

4

High-throughput

0.445

High

169125

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.445

High

169020

LKHA4
Leukotriene A-4 hydrolase

1

0

High-throughput

0.438

High

169024

CETP
Cholesteryl ester transfer protein

1

0

High-throughput

0.438

High

169120

OTUD5
OTU domain-containing protein 5

1

0

High-throughput

0.438

High

169036

CATS
Cathepsin S

1

1

High-throughput

0.437

High

169091

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.437

High

169100

CE128
Centrosomal protein of 128 kDa

1

3

High-throughput

0.437

High

169101

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.437

High

169107

NIN
Ninein

1

3

High-throughput

0.437

High

169129

ASXL3
Putative Polycomb group protein ASXL3

1

1

High-throughput

0.437

High

169021

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

169022

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

169026

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

169040

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

169067

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.426

High

169077

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

169140

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

169052

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

169004

CLU
Clustered mitochondria protein homolog

3

0

High-throughput

0.347

High

169093

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

3

0

High-throughput

0.347

High

169112

CHUR
Protein Churchill

2

0

High-throughput

0.318

High

169103

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

169105

FAM9A
Protein FAM9A

2

0

High-throughput

0.316

High

169108

RB8NL
RBBP8 N-terminal-like protein

2

0

High-throughput

0.316

High

169139

SYBU
Syntabulin

2

0

High-throughput

0.316

High

62663

PCARE
Photoreceptor cilium actin regulator

1

0

High-throughput

0.279

Low

169143

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

169000

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.249

Low

169010

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

169034

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.249

Low

169080

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

169099

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

169132

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

169149

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

169104

THNS2
Threonine synthase-like 2

1

0

High-throughput

0.238

Low

169002

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

169092

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024