Protein: PPR18
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)

Gene: PPR18, PPP1R18
Organism: Homo sapiens
Interactions: 142
UniProt ID: Q6NYC8

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0019902 - phosphatase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

905972

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

8

13

Small-scale

0.753

High

737870

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

8

13

Small-scale

0.750

High

536885

TRI27
Zinc finger protein RFP

4

5

High-throughput

0.703

High

1157449

CARD9
Caspase recruitment domain-containing protein 9

4

4

High-throughput

0.698

High

580042

K1C15
Keratin, type I cytoskeletal 15

3

7

High-throughput

0.675

High

1071222

K1H1
Keratin, type I cuticular Ha1

3

10

High-throughput

0.675

High

1127007

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

7

High-throughput

0.675

High

1147830

C102B
Coiled-coil domain-containing protein 102B

3

4

High-throughput

0.675

High

1157445

TRI54
Tripartite motif-containing protein 54

3

16

High-throughput

0.675

High

1157456

HOME3
Homer protein homolog 3

3

4

High-throughput

0.675

High

1157464

TRIM1
Probable E3 ubiquitin-protein ligase MID2

3

20

High-throughput

0.675

High

413958

GELS
Gelsolin

3

1

High-throughput

0.667

High

906501

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

3

13

High-throughput

0.667

High

369824

ESR1
Estrogen receptor

3

20

High-throughput

0.650

High

569092

DESM
Desmin

4

15

High-throughput

0.637

High

1025426

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

9

Small-scale

0.631

High

50928

FSD2
Fibronectin type III and SPRY domain-containing protein 2

3

17

High-throughput

0.616

High

269436

STX11
Syntaxin-11

3

1

High-throughput

0.616

High

994963

GOGA2
Golgin subfamily A member 2

3

6

High-throughput

0.616

High

1157421

VPS52
Vacuolar protein sorting-associated protein 52 homolog

3

1

High-throughput

0.616

High

1157423

KASH5
Protein KASH5

3

5

High-throughput

0.616

High

884320

PCBP3
Poly(rC)-binding protein 3

2

5

High-throughput

0.611

High

1137458

RAIN
Ras-interacting protein 1

3

8

High-throughput

0.609

High

61863

CC88B
Coiled-coil domain-containing protein 88B

2

8

High-throughput

0.606

High

235530

VINEX
Vinexin

2

15

High-throughput

0.606

High

280613

KRT34
Keratin, type I cuticular Ha4

2

10

High-throughput

0.606

High

443589

VIME
Vimentin

2

15

High-throughput

0.606

High

445071

K1C16
Keratin, type I cytoskeletal 16

2

9

High-throughput

0.606

High

535431

GFAP
Glial fibrillary acidic protein

2

15

High-throughput

0.606

High

658974

MK01
Mitogen-activated protein kinase 1

2

2

High-throughput

0.606

High

781918

PERI
Peripherin

2

15

High-throughput

0.606

High

869386

HAP1
Huntingtin-associated protein 1

2

4

High-throughput

0.606

High

1055056

KT33B
Keratin, type I cuticular Ha3-II

2

10

High-throughput

0.606

High

1157413

K1C27
Keratin, type I cytoskeletal 27

2

7

High-throughput

0.606

High

1157417

DZIP1
Cilium assembly protein DZIP1

2

7

High-throughput

0.606

High

1157426

BICD2
Protein bicaudal D homolog 2

2

13

High-throughput

0.606

High

1157431

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

2

2

High-throughput

0.606

High

1157435

HOOK2
Protein Hook homolog 2

2

6

High-throughput

0.606

High

1157439

ASPP1
Apoptosis-stimulating of p53 protein 1

2

9

High-throughput

0.606

High

1157443

TRI62
E3 ubiquitin-protein ligase TRIM62

2

4

High-throughput

0.606

High

1157454

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

7

High-throughput

0.606

High

1157460

ZRAN1
Ubiquitin thioesterase ZRANB1

2

8

High-throughput

0.606

High

1157467

LZTS1
Leucine zipper putative tumor suppressor 1

2

12

High-throughput

0.606

High

1157471

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

2

11

High-throughput

0.606

High

1157458

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.606

High

1157452

ECT2
Protein ECT2

2

8

High-throughput

0.584

High

1157455

ANLN
Anillin

2

3

High-throughput

0.584

High

1157416

CDR2L
Cerebellar degeneration-related protein 2-like

2

0

High-throughput

0.580

High

1157420

ABRA
Actin-binding Rho-activating protein

2

0

High-throughput

0.580

High

1157465

IKZF3
Zinc finger protein Aiolos

2

0

High-throughput

0.580

High

1157438

CC136
Coiled-coil domain-containing protein 136

2

7

High-throughput

0.578

High

422203

NFL
Neurofilament light polypeptide

1

16

High-throughput

0.573

High

444396

K1C19
Keratin, type I cytoskeletal 19

1

9

High-throughput

0.573

High

734659

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.573

High

1020738

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.573

High

1102739

CCD57
Coiled-coil domain-containing protein 57

1

10

High-throughput

0.573

High

1138258

MYOME
Myomegalin

1

2

High-throughput

0.573

High

1149178

K1C40
Keratin, type I cytoskeletal 40

1

10

High-throughput

0.573

High

1157414

TRI69
E3 ubiquitin-protein ligase TRIM69

1

5

High-throughput

0.573

High

1157446

TSG10
Testis-specific gene 10 protein

1

14

High-throughput

0.573

High

1118306

GRAP1
GRIP1-associated protein 1

2

4

High-throughput

0.561

High

1045173

NACA
Nascent polypeptide-associated complex subunit alpha

1

2

Small-scale

0.561

High

62331

GG6L9
Golgin subfamily A member 6-like protein 9

2

16

High-throughput

0.553

High

280807

KRT36
Keratin, type I cuticular Ha6

2

10

High-throughput

0.553

High

993259

ACTN3
Alpha-actinin-3

2

4

High-throughput

0.553

High

1136571

FHL5
Four and a half LIM domains protein 5

2

12

High-throughput

0.553

High

1157432

GCC1
GRIP and coiled-coil domain-containing protein 1

2

12

High-throughput

0.553

High

1157437

GMCL1
Germ cell-less protein-like 1

2

2

High-throughput

0.553

High

1157453

PKHF2
Pleckstrin homology domain-containing family F member 2

2

1

High-throughput

0.553

High

598172

FLNA
Filamin-A

1

10

High-throughput

0.536

High

809335

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

4

High-throughput

0.536

High

1084976

DREB
Drebrin

1

7

High-throughput

0.536

High

1157422

SYNPO
Synaptopodin

1

9

High-throughput

0.536

High

1157430

MY18A
Unconventional myosin-XVIIIa

1

4

High-throughput

0.536

High

1157436

MYO19
Unconventional myosin-XIX

1

4

High-throughput

0.536

High

1157470

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

551174

ITF2
Transcription factor 4

1

1

High-throughput

0.523

High

1157412

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.523

High

1157434

SPDLY
Protein Spindly

1

4

High-throughput

0.523

High

1157442

LZTS2
Leucine zipper putative tumor suppressor 2

1

17

High-throughput

0.523

High

111180

I6L9F6
NEFL protein

1

15

High-throughput

0.515

High

875032

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.513

High

1157466

PHF24
PHD finger protein 24

1

0

High-throughput

0.493

High

813071

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.489

High

1048107

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

7

High-throughput

0.489

High

1157450

CPVL
Probable serine carboxypeptidase CPVL

1

2

High-throughput

0.489

High

1157462

LIMA1
LIM domain and actin-binding protein 1

1

6

High-throughput

0.489

High

531482

K1C13
Keratin, type I cytoskeletal 13

1

8

High-throughput

0.481

High

838056

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

1157428

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

1157429

TSC1
Hamartin

1

15

High-throughput

0.481

High

233507

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

347066

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

502219

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

529272

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.479

High

547101

EZRI
Ezrin

1

4

High-throughput

0.479

High

749597

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

891838

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.479

High

1043875

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.479

High

1157411

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1157427

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.479

High

1157451

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

1157459

HDAC6
Histone deacetylase 6

1

7

High-throughput

0.479

High

49568

A1A4E9
Keratin 13

1

8

High-throughput

0.470

High

1116704

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1151073

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.470

High

1157415

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1030298

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1157457

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.458

High

1157463

SEPT9
Septin-9

1

0

Small-scale

0.458

High

882369

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.445

High

1157410

TMIG1
Transmembrane and immunoglobulin domain-containing protein 1

1

1

Small-scale

0.445

High

148947

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.437

High

308798

KI20A
Kinesin-like protein KIF20A

1

10

High-throughput

0.437

High

522007

CADH1
Cadherin-1

1

5

High-throughput

0.437

High

836837

DNLI4
DNA ligase 4

1

1

High-throughput

0.437

High

914143

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.437

High

1063869

TNIP1
TNFAIP3-interacting protein 1

1

15

High-throughput

0.437

High

1066268

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.437

High

1087831

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

1

High-throughput

0.437

High

1146509

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.437

High

1157461

TES
Testin

1

9

High-throughput

0.437

High

47160

A0A6Q8KRG2
Golgin subfamily A member 2

1

7

High-throughput

0.417

High

981611

REL
Proto-oncogene c-Rel

1

3

High-throughput

0.417

High

1157444

KIFC3
Kinesin-like protein KIFC3

1

2

High-throughput

0.417

High

717937

BMI1
Polycomb complex protein BMI-1

1

7

High-throughput

0.407

High

1032472

CTBP1
C-terminal-binding protein 1

1

5

High-throughput

0.407

High

1157441

ZBT18
Zinc finger and BTB domain-containing protein 18

1

1

High-throughput

0.407

High

1157447

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.407

High

1157418

TEX11
Testis-expressed protein 11

3

0

High-throughput

0.352

High

235284

OGA
Protein O-GlcNAcase

3

0

High-throughput

0.347

High

1157425

CEP70
Centrosomal protein of 70 kDa

3

0

High-throughput

0.339

High

253055

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

320692

LDOC1
Protein LDOC1

2

0

High-throughput

0.316

High

1157433

RM38
Large ribosomal subunit protein mL38

2

0

High-throughput

0.316

High

1157448

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1157468

EIF3L
Eukaryotic translation initiation factor 3 subunit L

2

0

High-throughput

0.316

High

1157469

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.316

High

1157419

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

1157424

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.299

High

758260

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.279

Low

1157440

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024