Protein: SH3R2
E3 ubiquitin-protein ligase SH3RF2 (EC 2.3.2.27) (Heart protein phosphatase 1-binding protein) (HEPP1) (POSH-eliminating RING protein) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (RING-type E3 ubiquitin transferase SH3RF2) (SH3 domain-containing RING finger protein 2)

Gene: SH3R2, SH3RF2
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q8TEC5

Gene Ontology (top 5):
GO:0004864 - protein phosphatase inhibitor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008157 - protein phosphatase 1 binding
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199519

EFS
Embryonal Fyn-associated substrate

2

20

High-throughput

0.700

High

896502

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

4

High-throughput

0.698

High

1127083

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

15

High-throughput

0.683

High

906037

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

5

Small-scale

0.680

High

1238465

BANP
Protein BANP

2

1

High-throughput

0.628

High

995079

GOGA2
Golgin subfamily A member 2

4

10

High-throughput

0.623

High

1256108

AMOL2
Angiomotin-like protein 2

4

13

High-throughput

0.623

High

872193

RD23A
UV excision repair protein RAD23 homolog A

1

6

Small-scale

0.618

High

1191849

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

19

Small-scale

0.618

High

314103

BAG4
BAG family molecular chaperone regulator 4

2

3

High-throughput

0.606

High

1256106

NEK6
Serine/threonine-protein kinase Nek6

2

13

High-throughput

0.606

High

737939

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

5

Small-scale

0.595

High

1220184

HOMEZ
Homeobox and leucine zipper protein Homez

2

2

High-throughput

0.584

High

1256107

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.580

High

1256101

RBPMS
RNA-binding protein with multiple splicing

2

2

High-throughput

0.576

High

60617

VP37C
Vacuolar protein sorting-associated protein 37C

2

20

High-throughput

0.553

High

67247

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

1147853

C102B
Coiled-coil domain-containing protein 102B

2

5

High-throughput

0.553

High

1043118

CUL4A
Cullin-4A

1

2

High-throughput

0.536

High

1216671

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

11

High-throughput

0.515

High

331051

PAK4
Serine/threonine-protein kinase PAK 4

1

20

Small-scale

0.512

High

395301

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

815701

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

8

Small-scale

0.501

High

1256103

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.493

High

364993

FRIL
Ferritin light chain

1

1

High-throughput

0.489

High

360200

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

9

High-throughput

0.481

High

432097

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

438388

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.479

High

640556

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

Small-scale

0.479

High

641864

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

Small-scale

0.479

High

925459

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.479

High

1030375

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

Small-scale

0.479

High

1256099

DDX1
ATP-dependent RNA helicase DDX1

1

2

Small-scale

0.479

High

1256105

CENPJ
Centromere protein J

1

3

High-throughput

0.470

High

1065549

SYK
Lysine--tRNA ligase

1

0

Small-scale

0.458

High

1189877

NUFP2
FMR1-interacting protein NUFIP2

1

0

Small-scale

0.458

High

1256104

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

Small-scale

0.458

High

1134030

AT7L2
Ataxin-7-like protein 2

1

2

High-throughput

0.439

High

1238868

CBY2
Protein chibby homolog 2

1

2

High-throughput

0.439

High

1256102

LZTS2
Leucine zipper putative tumor suppressor 2

1

19

High-throughput

0.439

High

603212

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

Small-scale

0.437

High

671483

ECHM
Enoyl-CoA hydratase, mitochondrial

1

2

Small-scale

0.437

High

892859

IF4A1
Eukaryotic initiation factor 4A-I

1

6

Small-scale

0.437

High

1109607

LSM12
Protein LSM12

1

1

Small-scale

0.437

High

1217685

CCD50
Coiled-coil domain-containing protein 50

1

1

Small-scale

0.437

High

1256100

FAN
Protein FAN

1

1

Small-scale

0.437

High

47166

A0A6Q8KRG2
Golgin subfamily A member 2

1

11

High-throughput

0.417

High

225005

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

571174

EGLN
Endoglin

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024