Protein: TB22B
TBC1 domain family member 22B

Gene: TB22B, TBC1D22B
Organism: Homo sapiens
Interactions: 196
UniProt ID: Q9NU19

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0071889 - 14-3-3 protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1259944

TB22A
TBC1 domain family member 22A

2

6

High-throughput

0.811

High

914391

RB11A
Ras-related protein Rab-11A

2

17

High-throughput

0.675

High

734790

TRI23
E3 ubiquitin-protein ligase TRIM23

5

19

High-throughput

0.654

High

1230728

VPS52
Vacuolar protein sorting-associated protein 52 homolog

4

2

High-throughput

0.637

High

1345852

TACC3
Transforming acidic coiled-coil-containing protein 3

4

2

High-throughput

0.637

High

1345833

TB22B
TBC1 domain family member 22B

1

6

High-throughput

0.621

High

1330267

GCP60
Golgi resident protein GCP60

3

1

Small-scale

0.615

High

995250

GOGA2
Golgin subfamily A member 2

3

1

High-throughput

0.613

High

982543

1433F
14-3-3 protein eta

3

20

High-throughput

0.609

High

844263

FXR2
RNA-binding protein FXR2

3

1

High-throughput

0.606

High

1043762

ASPP2
Apoptosis-stimulating of p53 protein 2

3

3

High-throughput

0.606

High

1317457

TRI54
Tripartite motif-containing protein 54

3

13

High-throughput

0.606

High

1127181

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

3

High-throughput

0.593

High

198479

KLK10
Kallikrein-10

2

2

High-throughput

0.574

High

234297

PEPL
Periplakin

2

6

High-throughput

0.574

High

245846

CATL2
Cathepsin L2

2

3

High-throughput

0.574

High

259893

LX12B
Arachidonate 12-lipoxygenase, 12R-type

2

1

High-throughput

0.574

High

271895

SPB7
Serpin B7

2

7

High-throughput

0.574

High

344342

AACT
Alpha-1-antichymotrypsin

2

6

High-throughput

0.574

High

396812

S10A8
Protein S100-A8

2

6

High-throughput

0.574

High

416524

S10A9
Protein S100-A9

2

8

High-throughput

0.574

High

427930

CAN1
Calpain-1 catalytic subunit

2

7

High-throughput

0.574

High

428640

INVO
Involucrin

2

1

High-throughput

0.574

High

445241

STS
Steryl-sulfatase

2

1

High-throughput

0.574

High

453990

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

2

3

High-throughput

0.574

High

577507

IL1RA
Interleukin-1 receptor antagonist protein

2

1

High-throughput

0.574

High

611349

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

2

High-throughput

0.574

High

629191

ZA2G
Zinc-alpha-2-glycoprotein

2

1

High-throughput

0.574

High

639098

S100P
Protein S100-P

2

8

High-throughput

0.574

High

668046

SPB3
Serpin B3

2

7

High-throughput

0.574

High

675659

ILEU
Leukocyte elastase inhibitor

2

7

High-throughput

0.574

High

678514

S10A7
Protein S100-A7

2

8

High-throughput

0.574

High

683147

CASPE
Caspase-14

2

1

High-throughput

0.574

High

738814

SPB5
Serpin B5

2

7

High-throughput

0.574

High

768452

CAPG
Macrophage-capping protein

2

2

High-throughput

0.574

High

776833

STAT3
Signal transducer and activator of transcription 3

2

1

High-throughput

0.574

High

815033

LEG7
Galectin-7

2

2

High-throughput

0.574

High

820396

SPB4
Serpin B4

2

7

High-throughput

0.574

High

836337

KLK7
Kallikrein-7

2

1

High-throughput

0.574

High

839509

SPB8
Serpin B8

2

7

High-throughput

0.574

High

872923

ARSF
Arylsulfatase F

2

1

High-throughput

0.574

High

885322

EPIPL
Epiplakin

2

6

High-throughput

0.574

High

905166

1433G
14-3-3 protein gamma

2

20

High-throughput

0.574

High

970851

DSG1
Desmoglein-1

2

6

High-throughput

0.574

High

994015

TGM3
Protein-glutamine gamma-glutamyltransferase E

2

2

High-throughput

0.574

High

1048806

TRI29
Tripartite motif-containing protein 29

2

4

High-throughput

0.574

High

1078460

CH3L2
Chitinase-3-like protein 2

2

1

High-throughput

0.574

High

1109805

PA24E
Cytosolic phospholipase A2 epsilon

2

1

High-throughput

0.574

High

1197660

S1A7A
Protein S100-A7A

2

7

High-throughput

0.574

High

1237327

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.574

High

1243655

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

2

1

High-throughput

0.574

High

1255833

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

2

3

High-throughput

0.574

High

1271315

EVPL
Envoplakin

2

6

High-throughput

0.574

High

1291400

S10AG
Protein S100-A16

2

8

High-throughput

0.574

High

1296799

CPNS2
Calpain small subunit 2

2

9

High-throughput

0.574

High

1345838

CALL5
Calmodulin-like protein 5

2

8

High-throughput

0.574

High

1345840

I36RA
Interleukin-36 receptor antagonist protein

2

1

High-throughput

0.574

High

1345841

CBPA4
Carboxypeptidase A4

2

1

High-throughput

0.574

High

1345842

SPB13
Serpin B13

2

7

High-throughput

0.574

High

1345843

CLC4K
C-type lectin domain family 4 member K

2

1

High-throughput

0.574

High

1345849

NEUR2
Sialidase-2

2

1

High-throughput

0.574

High

235599

VINEX
Vinexin

2

1

High-throughput

0.573

High

537090

TRI27
Zinc finger protein RFP

2

2

High-throughput

0.573

High

985739

DEUP1
Deuterosome assembly protein 1

2

5

High-throughput

0.573

High

1149365

K1C40
Keratin, type I cytoskeletal 40

2

4

High-throughput

0.573

High

1299834

PNMA5
Paraneoplastic antigen-like protein 5

2

1

High-throughput

0.573

High

913139

ARF6
ADP-ribosylation factor 6

2

12

High-throughput

0.558

High

61882

CC88B
Coiled-coil domain-containing protein 88B

2

3

High-throughput

0.553

High

280735

KRT34
Keratin, type I cuticular Ha4

2

4

High-throughput

0.553

High

535582

GFAP
Glial fibrillary acidic protein

2

6

High-throughput

0.553

High

816287

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

2

2

High-throughput

0.553

High

843932

FXR1
RNA-binding protein FXR1

2

1

High-throughput

0.553

High

981747

REL
Proto-oncogene c-Rel

2

1

High-throughput

0.553

High

1044718

FHL3
Four and a half LIM domains protein 3

2

2

High-throughput

0.553

High

1076550

TRIP6
Thyroid receptor-interacting protein 6

2

3

High-throughput

0.553

High

1127595

EFHC2
EF-hand domain-containing family member C2

2

8

High-throughput

0.553

High

1148494

LHX8
LIM/homeobox protein Lhx8

2

2

High-throughput

0.553

High

1239111

ZSCA4
Zinc finger and SCAN domain-containing protein 4

2

2

High-throughput

0.553

High

1289563

HOOK2
Protein Hook homolog 2

2

3

High-throughput

0.553

High

1298069

CEP63
Centrosomal protein of 63 kDa

2

4

High-throughput

0.553

High

1298409

AP4AT
AP-4 complex accessory subunit Tepsin

2

1

High-throughput

0.553

High

1313792

KIFC3
Kinesin-like protein KIFC3

2

2

High-throughput

0.553

High

1314856

CAR10
Caspase recruitment domain-containing protein 10

2

3

High-throughput

0.553

High

1342335

HM20A
High mobility group protein 20A

2

1

High-throughput

0.553

High

1345506

HOME3
Homer protein homolog 3

2

3

High-throughput

0.553

High

1345844

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

17

High-throughput

0.553

High

348954

RASN
GTPase NRas

1

20

High-throughput

0.553

High

592033

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.553

High

592528

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.553

High

845763

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.553

High

884602

RAB25
Ras-related protein Rab-25

1

18

High-throughput

0.553

High

1130643

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.536

High

72353

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

2

1

High-throughput

0.533

High

507261

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.533

High

1025569

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

8

High-throughput

0.523

High

1102809

CCD57
Coiled-coil domain-containing protein 57

1

1

High-throughput

0.523

High

1216721

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.523

High

66448

A2ML1
Alpha-2-macroglobulin-like protein 1

2

1

High-throughput

0.504

High

353564

IGKC
Immunoglobulin kappa constant

2

3

High-throughput

0.504

High

862110

DAPK1
Death-associated protein kinase 1

1

2

High-throughput

0.489

High

1345850

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

3

High-throughput

0.489

High

362296

GLPA
Glycophorin-A

1

1

High-throughput

0.489

High

454767

TACD2
Tumor-associated calcium signal transducer 2

1

5

High-throughput

0.489

High

533996

ANXA8
Annexin A8

1

1

High-throughput

0.489

High

537184

CBPM
Carboxypeptidase M

1

1

High-throughput

0.489

High

551852

DESP
Desmoplakin

1

6

High-throughput

0.489

High

596328

FILA
Filaggrin

1

5

High-throughput

0.489

High

683751

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.489

High

910079

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.489

High

927576

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.489

High

1044327

FCL
GDP-L-fucose synthase

1

1

High-throughput

0.489

High

1078233

CD226
CD226 antigen

1

5

High-throughput

0.489

High

1125355

FILA2
Filaggrin-2

1

5

High-throughput

0.489

High

1204656

PA24D
Cytosolic phospholipase A2 delta

1

1

High-throughput

0.489

High

1240798

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.489

High

1263036

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

2

High-throughput

0.489

High

1316989

LOXE3
Hydroperoxide isomerase ALOXE3

1

1

High-throughput

0.489

High

1345835

ARL8B
ADP-ribosylation factor-like protein 8B

1

19

High-throughput

0.489

High

169626

BET1
BET1 homolog

1

4

High-throughput

0.437

High

178809

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

206037

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.437

High

213023

STX6
Syntaxin-6

1

4

High-throughput

0.437

High

305648

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

508219

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.437

High

522219

CADH1
Cadherin-1

1

4

High-throughput

0.437

High

527833

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.437

High

567294

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.437

High

872495

EPHA5
Ephrin type-A receptor 5

1

7

High-throughput

0.437

High

897408

ARF3
ADP-ribosylation factor 3

1

10

High-throughput

0.437

High

950566

ARF1
ADP-ribosylation factor 1

1

10

High-throughput

0.437

High

950725

ARF5
ADP-ribosylation factor 5

1

10

High-throughput

0.437

High

975063

CAV1
Caveolin-1

1

1

High-throughput

0.437

High

1148238

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.437

High

1152135

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

1203872

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1230398

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

1345847

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.437

High

47172

A0A6Q8KRG2
Golgin subfamily A member 2

1

3

High-throughput

0.417

High

353738

IGHG1
Immunoglobulin heavy constant gamma 1

1

3

High-throughput

0.407

High

353825

IGHG2
Immunoglobulin heavy constant gamma 2

1

3

High-throughput

0.407

High

1345853

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

2

Small-scale

0.407

High

1345845

IKZF3
Zinc finger protein Aiolos

5

0

High-throughput

0.373

High

1308593

DHB14
17-beta-hydroxysteroid dehydrogenase 14

4

0

High-throughput

0.364

High

120101

ST2B1
Sulfotransferase 2B1

2

0

High-throughput

0.328

High

224588

AK1BA
Aldo-keto reductase family 1 member B10

2

0

High-throughput

0.328

High

452282

HMOX1
Heme oxygenase 1

2

0

High-throughput

0.328

High

543076

GLNA
Glutamine synthetase

2

0

High-throughput

0.328

High

546894

PPAP
Prostatic acid phosphatase

2

0

High-throughput

0.328

High

572152

SAP3
Ganglioside GM2 activator

2

0

High-throughput

0.328

High

588456

TYPH
Thymidine phosphorylase

2

0

High-throughput

0.328

High

787791

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.328

High

945746

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.328

High

1083780

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.328

High

1159705

PLBL1
Phospholipase B-like 1

2

0

High-throughput

0.328

High

1165493

SBSN
Suprabasin

2

0

High-throughput

0.328

High

1202837

NAL10
NACHT, LRR and PYD domains-containing protein 10

2

0

High-throughput

0.328

High

1232737

RDHE2
Epidermal retinol dehydrogenase 2

2

0

High-throughput

0.328

High

1261823

POF1B
Protein POF1B

2

0

High-throughput

0.328

High

1300240

GSDMA
Gasdermin-A

2

0

High-throughput

0.328

High

1327964

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.328

High

1345851

CRBG1
Beta/gamma crystallin domain-containing protein 1

2

0

High-throughput

0.328

High

967630

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.327

High

200792

ARHG9
Rho guanine nucleotide exchange factor 9

2

0

High-throughput

0.316

High

735110

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

1014090

AP1B1
AP-1 complex subunit beta-1

2

0

High-throughput

0.316

High

1123333

PKHG4
Puratrophin-1

2

0

High-throughput

0.316

High

1130100

RBM48
RNA-binding protein 48

2

0

High-throughput

0.316

High

1190662

ZN438
Zinc finger protein 438

2

0

High-throughput

0.316

High

1223271

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.316

High

1242237

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.316

High

1245794

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

1257169

ZFP90
Zinc finger protein 90 homolog

2

0

High-throughput

0.316

High

1287675

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1329397

GO45
Golgin-45

2

0

High-throughput

0.316

High

1344647

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1345846

SPAT2
Spermatogenesis-associated protein 2

2

0

High-throughput

0.316

High

1345848

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.316

High

958143

RBM10
RNA-binding protein 10

1

0

High-throughput

0.299

High

1223134

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.299

High

158705

FSCN2
Fascin-2

1

0

High-throughput

0.279

Low

306595

SCEL
Sciellin

1

0

High-throughput

0.279

Low

1037492

ASAH1
Acid ceramidase

1

0

High-throughput

0.279

Low

1079066

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1173108

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

1184891

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.279

Low

1328673

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

1345836

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.279

Low

132609

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

1333591

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

1345834

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1345837

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1345839

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1029333

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.232

Low

1121437

P5CR3
Pyrroline-5-carboxylate reductase 3

1

0

Small-scale

0.232

Low

1273914

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024