Protein: NVL
Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein)

Gene: NVL
Organism: Homo sapiens
Interactions: 157
UniProt ID: O15381

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005697 - telomerase holoenzyme complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

177436

NPM
Nucleophosmin

4

2

High-throughput

0.699

High

177479

RS6
Small ribosomal subunit protein eS6

3

3

High-throughput

0.656

High

177504

IF16
Gamma-interferon-inducible protein 16

3

4

High-throughput

0.656

High

177526

PRR11
Proline-rich protein 11

3

0

High-throughput

0.638

High

132054

PESC
Pescadillo homolog

2

2

High-throughput

0.628

High

177461

RBM34
RNA-binding protein 34

2

3

High-throughput

0.628

High

177530

ZN512
Zinc finger protein 512

2

3

High-throughput

0.628

High

177537

RBM4
RNA-binding protein 4

2

4

High-throughput

0.628

High

177434

HSPB1
Heat shock protein beta-1

2

2

High-throughput

0.628

High

177486

RED1
Double-stranded RNA-specific editase 1

2

2

High-throughput

0.614

High

177485

RNF4
E3 ubiquitin-protein ligase RNF4

2

3

High-throughput

0.606

High

177419

RRP8
Ribosomal RNA-processing protein 8

2

0

High-throughput

0.602

High

177469

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.602

High

177505

PKHO1
Pleckstrin homology domain-containing family O member 1

2

0

High-throughput

0.602

High

177523

DGCR8
Microprocessor complex subunit DGCR8

2

0

High-throughput

0.602

High

177538

MAK16
Protein MAK16 homolog

2

0

High-throughput

0.602

High

177544

SSF1
Suppressor of SWI4 1 homolog

2

0

High-throughput

0.602

High

177546

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

2

0

High-throughput

0.602

High

92128

E9PAV9
G patch domain-containing protein 4

2

2

High-throughput

0.584

High

177424

BRD4
Bromodomain-containing protein 4

2

9

High-throughput

0.584

High

177433

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

177437

PARP1
Poly [ADP-ribose] polymerase 1

2

2

High-throughput

0.584

High

177472

FGF8
Fibroblast growth factor 8

2

1

High-throughput

0.574

High

177556

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.553

High

171707

WDR46
WD repeat-containing protein 46

1

4

High-throughput

0.536

High

177418

MAGB2
Melanoma-associated antigen B2

1

2

High-throughput

0.536

High

177426

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

4

High-throughput

0.536

High

177427

NPM3
Nucleoplasmin-3

1

3

High-throughput

0.536

High

177432

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.536

High

177435

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.536

High

177441

RL17
Large ribosomal subunit protein uL22

1

5

High-throughput

0.536

High

177444

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

2

High-throughput

0.536

High

177445

H1T
Histone H1t

1

1

High-throughput

0.536

High

177447

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

177453

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

177457

RL13A
Large ribosomal subunit protein uL13

1

4

High-throughput

0.536

High

177459

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.536

High

177463

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

177465

NOP2
Probable 28S rRNA

1

1

High-throughput

0.536

High

177466

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

177474

RL15
Large ribosomal subunit protein eL15

1

2

High-throughput

0.536

High

177475

RHOA
Transforming protein RhoA

1

10

High-throughput

0.536

High

177476

RS14
Small ribosomal subunit protein uS11

1

2

High-throughput

0.536

High

177477

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.536

High

177478

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

177489

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.536

High

177493

RL18
Large ribosomal subunit protein eL18

1

2

High-throughput

0.536

High

177495

ILF3
Interleukin enhancer-binding factor 3

1

4

High-throughput

0.536

High

177498

SRSF6
Serine/arginine-rich splicing factor 6

1

5

High-throughput

0.536

High

177499

CUL3
Cullin-3

1

12

High-throughput

0.536

High

177500

EXOS2
Exosome complex component RRP4

1

2

High-throughput

0.536

High

177512

KI21A
Kinesin-like protein KIF21A

1

2

High-throughput

0.536

High

177513

ZN467
Zinc finger protein 467

1

1

High-throughput

0.536

High

177515

CUL9
Cullin-9

1

8

High-throughput

0.536

High

177520

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

2

High-throughput

0.536

High

177529

MAGBA
Melanoma-associated antigen B10

1

2

High-throughput

0.536

High

177547

DDX21
Nucleolar RNA helicase 2

1

3

High-throughput

0.536

High

177552

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

177554

ZBT47
Zinc finger and BTB domain-containing protein 47

1

2

High-throughput

0.536

High

177555

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

177560

SRPK3
SRSF protein kinase 3

1

6

High-throughput

0.536

High

177565

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.536

High

177420

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.515

High

177422

KIF1B
Kinesin-like protein KIF1B

1

5

High-throughput

0.515

High

177438

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

5

High-throughput

0.515

High

177449

NOS3
Nitric oxide synthase 3

1

3

High-throughput

0.515

High

177450

MERL
Merlin

1

5

High-throughput

0.515

High

177455

SYUA
Alpha-synuclein

1

1

High-throughput

0.515

High

177460

PERI
Peripherin

1

5

High-throughput

0.515

High

177471

ATX1
Ataxin-1

1

3

High-throughput

0.515

High

177473

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

2

High-throughput

0.515

High

177488

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.515

High

177497

TADBP
TAR DNA-binding protein 43

1

4

High-throughput

0.515

High

177502

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.515

High

177562

RNF11
RING finger protein 11

1

6

High-throughput

0.515

High

177566

TF3C3
General transcription factor 3C polypeptide 3

1

2

High-throughput

0.515

High

177442

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

177454

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

177467

CDX1
Homeobox protein CDX-1

1

0

High-throughput

0.513

High

177483

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

177508

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

177521

PHF10
PHD finger protein 10

1

0

High-throughput

0.513

High

177532

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.513

High

177534

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.513

High

177549

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

177557

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

177484

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.508

High

177543

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.508

High

177559

TTF2
Transcription termination factor 2

1

5

Small-scale

0.508

High

177501

DPYL1
Dihydropyrimidinase-related protein 1

1

7

High-throughput

0.494

High

47179

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

177490

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

177425

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.489

High

177514

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

177563

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

122373

MEN1
Menin

1

2

High-throughput

0.479

High

148148

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

177421

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

177423

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

177430

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

177431

KI20A
Kinesin-like protein KIF20A

1

10

High-throughput

0.479

High

177439

ANDR
Androgen receptor

1

10

High-throughput

0.479

High

177440

XRCC6
X-ray repair cross-complementing protein 6

1

4

High-throughput

0.479

High

177448

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

177451

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

177452

RL22
Large ribosomal subunit protein eL22

1

2

High-throughput

0.479

High

177456

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

177458

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

177464

RECQ1
ATP-dependent DNA helicase Q1

1

6

High-throughput

0.479

High

177468

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.479

High

177480

H2B1C
Histone H2B type 1-C/E/F/G/I

1

2

High-throughput

0.479

High

177481

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.479

High

177482

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

177487

H33
Histone H3.3

1

6

High-throughput

0.479

High

177491

EXOSX
Exosome complex component 10

1

3

High-throughput

0.479

High

177492

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

177494

ILF2
Interleukin enhancer-binding factor 2

1

2

High-throughput

0.479

High

177496

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.479

High

177503

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

177507

IFIX
Pyrin and HIN domain-containing protein 1

1

4

High-throughput

0.479

High

177516

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

177517

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

177518

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

177522

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

177524

ESR2
Estrogen receptor beta

1

10

High-throughput

0.479

High

177527

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

177528

CEP19
Centrosomal protein of 19 kDa

1

1

High-throughput

0.479

High

177533

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

177535

VRK1
Serine/threonine-protein kinase VRK1

1

1

High-throughput

0.479

High

177536

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

177539

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

High-throughput

0.479

High

177540

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

177542

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

177545

ANLN
Anillin

1

3

High-throughput

0.479

High

177548

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

177550

DCA13
DDB1- and CUL4-associated factor 13

1

8

Small-scale

0.479

High

177551

DJC17
DnaJ homolog subfamily C member 17

1

7

High-throughput

0.479

High

177553

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

177558

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.479

High

177561

CE164
Centrosomal protein of 164 kDa

1

5

High-throughput

0.479

High

177417

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

177462

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

177511

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

177564

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

66784

A8KAG1
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

177506

GPTC4
G patch domain-containing protein 4

1

2

High-throughput

0.445

High

177510

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

177525

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.437

High

177541

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

177509

Q6T424
Tumor differentiation factor

1

0

Small-scale

0.426

High

177519

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

5

High-throughput

0.407

High

177443

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

2

0

High-throughput

0.324

High

177428

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.279

Low

177446

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

177470

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

177531

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

177429

WFS1
Wolframin

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024