Protein: ATF3
Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3)

Gene: ATF3
Organism: Homo sapiens
Interactions: 104
UniProt ID: P18847

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

401392

JUN
Transcription factor Jun

10

20

Small-scale

0.976

High

566719

JUNB
Transcription factor JunB

5

20

High-throughput

0.931

High

579169

ATF4
Cyclic AMP-dependent transcription factor ATF-4

3

15

Small-scale

0.879

High

568060

JUND
Transcription factor JunD

3

20

Small-scale

0.873

High

547696

ATF2
Cyclic AMP-dependent transcription factor ATF-2

3

19

High-throughput

0.857

High

579184

CEBPG
CCAAT/enhancer-binding protein gamma

3

20

High-throughput

0.835

High

579229

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

3

20

High-throughput

0.835

High

569156

CEBPB
CCAAT/enhancer-binding protein beta

3

20

Small-scale

0.834

High

579168

ATF3
Cyclic AMP-dependent transcription factor ATF-3

2

20

Small-scale

0.807

High

568242

ATF7
Cyclic AMP-dependent transcription factor ATF-7

2

20

High-throughput

0.799

High

579212

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.778

High

579197

TF65
Transcription factor p65

1

20

Small-scale

0.770

High

579179

CEBPA
CCAAT/enhancer-binding protein alpha

2

20

High-throughput

0.768

High

579173

DDIT3
DNA damage-inducible transcript 3 protein

10

16

Small-scale

0.759

High

579192

MDM2
E3 ubiquitin-protein ligase Mdm2

6

4

Small-scale

0.742

High

386064

P53
Cellular tumor antigen p53

5

6

Small-scale

0.729

High

317906

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

20

High-throughput

0.691

High

181916

MAFG
Transcription factor MafG

1

20

High-throughput

0.647

High

216664

CREB3
Cyclic AMP-responsive element-binding protein 3

1

20

High-throughput

0.647

High

345318

FOS
Protein c-Fos

1

20

High-throughput

0.647

High

548219

FOSL1
Fos-related antigen 1

1

19

High-throughput

0.647

High

548281

FOSL2
Fos-related antigen 2

1

20

High-throughput

0.647

High

579200

DBP
D site-binding protein

1

20

High-throughput

0.647

High

579210

CEBPE
CCAAT/enhancer-binding protein epsilon

1

20

High-throughput

0.647

High

579213

BATF
Basic leucine zipper transcriptional factor ATF-like

1

20

High-throughput

0.647

High

579235

MAFF
Transcription factor MafF

1

20

High-throughput

0.647

High

579237

MAFB
Transcription factor MafB

1

20

High-throughput

0.647

High

579191

SMAD3
Mothers against decapentaplegic homolog 3

2

14

Small-scale

0.624

High

579181

SMCA4
Transcription activator BRG1

2

11

Small-scale

0.601

High

579204

HDAC1
Histone deacetylase 1

2

20

Small-scale

0.595

High

579209

ELAV1
ELAV-like protein 1

2

3

Small-scale

0.584

High

579175

STAT3
Signal transducer and activator of transcription 3

2

14

High-throughput

0.576

High

579177

CRK
Adapter molecule crk

2

5

High-throughput

0.576

High

579218

DP13B
DCC-interacting protein 13-beta

2

1

High-throughput

0.576

High

579206

FHL2
Four and a half LIM domains protein 2

1

8

Small-scale

0.573

High

579232

HDAC6
Histone deacetylase 6

1

20

Small-scale

0.573

High

175820

P73
Tumor protein p73

1

6

Small-scale

0.561

High

265848

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

16

Small-scale

0.561

High

579176

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

14

Small-scale

0.561

High

579183

PDX1
Pancreas/duodenum homeobox protein 1

1

9

Small-scale

0.561

High

579220

CBP
CREB-binding protein

1

20

Small-scale

0.561

High

579222

KAT5
Histone acetyltransferase KAT5

1

4

Small-scale

0.561

High

579227

P63
Tumor protein 63

1

6

Small-scale

0.561

High

243128

SH21A
SH2 domain-containing protein 1A

2

7

High-throughput

0.542

High

257450

CREST
Calcium-responsive transactivator

1

16

High-throughput

0.541

High

579170

FGFR3
Fibroblast growth factor receptor 3

1

7

High-throughput

0.541

High

455074

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.536

High

579172

RBTN1
Rhombotin-1

1

8

High-throughput

0.536

High

579190

TPM4
Tropomyosin alpha-4 chain

1

15

High-throughput

0.536

High

579194

MEF2A
Myocyte-specific enhancer factor 2A

1

6

High-throughput

0.536

High

579208

TEAD2
Transcriptional enhancer factor TEF-4

1

3

High-throughput

0.536

High

579231

DOK5
Docking protein 5

2

2

High-throughput

0.526

High

402706

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.518

High

579185

ATX1
Ataxin-1

1

2

High-throughput

0.515

High

579202

TADBP
TAR DNA-binding protein 43

1

10

High-throughput

0.515

High

203624

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.508

High

579195

ID3
DNA-binding protein inhibitor ID-3

1

1

Small-scale

0.508

High

579233

ZN212
Zinc finger protein 212

1

4

Small-scale

0.508

High

177189

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.501

High

579186

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.501

High

579189

UBC9
SUMO-conjugating enzyme UBC9

1

6

Small-scale

0.501

High

579228

SRA1
Steroid receptor RNA activator 1

1

5

Small-scale

0.501

High

579234

DNM3L
DNA

1

8

Small-scale

0.501

High

579236

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.501

High

456494

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.493

High

579174

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

579221

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

280950

KRT38
Keratin, type I cuticular Ha8

1

7

High-throughput

0.489

High

538636

MYL6B
Myosin light chain 6B

1

7

High-throughput

0.489

High

579171

EF1B
Elongation factor 1-beta

1

10

High-throughput

0.489

High

579178

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.489

High

579182

CAZA1
F-actin-capping protein subunit alpha-1

1

2

High-throughput

0.489

High

579199

CALD1
Caldesmon

1

9

High-throughput

0.489

High

579225

COR1B
Coronin-1B

1

8

High-throughput

0.489

High

579214

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

1

High-throughput

0.481

High

579217

UBR2
E3 ubiquitin-protein ligase UBR2

1

3

Small-scale

0.481

High

122488

MEN1
Menin

1

8

High-throughput

0.479

High

345885

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

377076

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

431516

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.479

High

437878

HS90B
Heat shock protein HSP 90-beta

1

11

High-throughput

0.479

High

505188

EGR2
E3 SUMO-protein ligase EGR2

1

7

High-throughput

0.479

High

579180

GSK3B
Glycogen synthase kinase-3 beta

1

5

Small-scale

0.479

High

579187

ACTB
Actin, cytoplasmic 1

1

2

Small-scale

0.479

High

579188

H4
Histone H4

1

9

High-throughput

0.479

High

579193

EWS
RNA-binding protein EWS

1

4

High-throughput

0.479

High

579196

ERCC6
DNA excision repair protein ERCC-6

1

13

Small-scale

0.479

High

579198

TLE3
Transducin-like enhancer protein 3

1

14

High-throughput

0.479

High

579201

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

579203

ERCC8
DNA excision repair protein ERCC-8

1

11

Small-scale

0.479

High

579205

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

12

Small-scale

0.479

High

579211

SMAD2
Mothers against decapentaplegic homolog 2

1

14

Small-scale

0.479

High

579219

COP1
E3 ubiquitin-protein ligase COP1

1

17

High-throughput

0.479

High

579223

HDA10
Polyamine deacetylase HDAC10

1

20

Small-scale

0.479

High

579230

SLX9
Ribosome biogenesis protein SLX9 homolog

1

1

Small-scale

0.479

High

579207

DCTN1
Dynactin subunit 1

1

6

High-throughput

0.470

High

579215

RIF1
Telomere-associated protein RIF1

1

8

High-throughput

0.457

High

579226

NUF2
Kinetochore protein Nuf2

1

5

High-throughput

0.457

High

579216

UBR1
E3 ubiquitin-protein ligase UBR1

1

3

Small-scale

0.439

High

372729

MMP1
Interstitial collagenase

1

9

Small-scale

0.437

High

438907

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

3

Small-scale

0.437

High

579224

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

47196

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024