Protein: CCNC
Cyclin-C (SRB11 homolog) (hSRB11)

Gene: CCNC
Organism: Homo sapiens
Interactions: 201
UniProt ID: P24863

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016592 - mediator complex
GO:0016538 - cyclin-dependent protein serine/threonine kinase regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

624411

CDK8
Cyclin-dependent kinase 8

26

20

Small-scale

0.992

High

624503

CDK19
Cyclin-dependent kinase 19

9

20

Small-scale

0.970

High

624422

CDK3
Cyclin-dependent kinase 3

4

20

Small-scale

0.894

High

624395

CCNC
Cyclin-C

2

11

High-throughput

0.783

High

624499

MED10
Mediator of RNA polymerase II transcription subunit 10

8

2

Small-scale

0.750

High

48617

MED19
Mediator of RNA polymerase II transcription subunit 19

8

1

Small-scale

0.749

High

624509

MED28
Mediator of RNA polymerase II transcription subunit 28

7

1

High-throughput

0.743

High

624435

MED1
Mediator of RNA polymerase II transcription subunit 1

7

3

Small-scale

0.741

High

624515

MED4
Mediator of RNA polymerase II transcription subunit 4

6

1

High-throughput

0.733

High

624520

MED29
Mediator of RNA polymerase II transcription subunit 29

6

1

High-throughput

0.733

High

270479

MED6
Mediator of RNA polymerase II transcription subunit 6

6

2

Small-scale

0.729

High

624480

MED12
Mediator of RNA polymerase II transcription subunit 12

6

6

Small-scale

0.727

High

624429

MED21
Mediator of RNA polymerase II transcription subunit 21

5

1

High-throughput

0.718

High

624537

MED31
Mediator of RNA polymerase II transcription subunit 31

5

1

High-throughput

0.718

High

225346

MED14
Mediator of RNA polymerase II transcription subunit 14

5

12

High-throughput

0.714

High

624434

MED22
Mediator of RNA polymerase II transcription subunit 22

5

1

High-throughput

0.714

High

624448

MED27
Mediator of RNA polymerase II transcription subunit 27

5

1

High-throughput

0.714

High

624500

MED18
Mediator of RNA polymerase II transcription subunit 18

5

1

High-throughput

0.714

High

624511

MED20
Mediator of RNA polymerase II transcription subunit 20

5

1

High-throughput

0.714

High

624525

MED13
Mediator of RNA polymerase II transcription subunit 13

5

5

High-throughput

0.712

High

624531

MED23
Mediator of RNA polymerase II transcription subunit 23

5

1

High-throughput

0.709

High

624457

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

5

4

High-throughput

0.706

High

206605

MED7
Mediator of RNA polymerase II transcription subunit 7

4

3

High-throughput

0.694

High

624519

MED9
Mediator of RNA polymerase II transcription subunit 9

4

1

High-throughput

0.694

High

624523

MED11
Mediator of RNA polymerase II transcription subunit 11

4

1

High-throughput

0.694

High

624415

CCNH
Cyclin-H

1

10

Small-scale

0.692

High

265303

MED24
Mediator of RNA polymerase II transcription subunit 24

4

1

High-throughput

0.686

High

624463

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

4

12

High-throughput

0.686

High

624485

MED8
Mediator of RNA polymerase II transcription subunit 8

4

1

High-throughput

0.686

High

624493

MED15
Mediator of RNA polymerase II transcription subunit 15

4

2

High-throughput

0.686

High

624518

MED17
Mediator of RNA polymerase II transcription subunit 17

4

1

High-throughput

0.686

High

624535

MED16
Mediator of RNA polymerase II transcription subunit 16

4

1

High-throughput

0.686

High

369004

ESR1
Estrogen receptor

3

19

Small-scale

0.660

High

624494

MINT
Msx2-interacting protein

3

8

High-throughput

0.656

High

624482

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

1

High-throughput

0.644

High

563351

ZNF18
Zinc finger protein 18

3

0

High-throughput

0.643

High

624458

MED25
Mediator of RNA polymerase II transcription subunit 25

3

0

High-throughput

0.638

High

624486

MED30
Mediator of RNA polymerase II transcription subunit 30

3

0

High-throughput

0.638

High

624414

MEOX2
Homeobox protein MOX-2

2

2

High-throughput

0.633

High

197661

CRX
Cone-rod homeobox protein

2

1

High-throughput

0.628

High

624513

TRI39
E3 ubiquitin-protein ligase TRIM39

2

2

High-throughput

0.628

High

624423

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

624432

K1H1
Keratin, type I cuticular Ha1

3

7

High-throughput

0.616

High

313393

MED26
Mediator of RNA polymerase II transcription subunit 26

2

2

High-throughput

0.611

High

624421

NGAL
Neutrophil gelatinase-associated lipocalin

3

1

High-throughput

0.607

High

445006

K1C16
Keratin, type I cytoskeletal 16

2

8

High-throughput

0.606

High

473640

ZN688
Zinc finger protein 688

2

1

High-throughput

0.606

High

551973

RFA2
Replication protein A 32 kDa subunit

2

8

High-throughput

0.606

High

624405

VHL
von Hippel-Lindau disease tumor suppressor

2

1

High-throughput

0.606

High

624407

CDN2B
Cyclin-dependent kinase 4 inhibitor B

2

5

High-throughput

0.606

High

624418

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

20

High-throughput

0.606

High

624419

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

4

High-throughput

0.606

High

624420

PO6F2
POU domain, class 6, transcription factor 2

2

4

High-throughput

0.606

High

624424

PAX5
Paired box protein Pax-5

2

1

High-throughput

0.606

High

624425

REL
Proto-oncogene c-Rel

2

3

High-throughput

0.606

High

624468

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

4

High-throughput

0.606

High

624471

CCHCR
Coiled-coil alpha-helical rod protein 1

2

1

High-throughput

0.606

High

624501

ZN426
Zinc finger protein 426

2

1

High-throughput

0.606

High

624512

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

0

High-throughput

0.601

High

414170

RB
Retinoblastoma-associated protein

1

12

Small-scale

0.589

High

243947

BRD4
Bromodomain-containing protein 4

2

16

High-throughput

0.584

High

328496

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.580

High

624406

RFC5
Replication factor C subunit 5

2

0

High-throughput

0.580

High

624439

ZN792
Zinc finger protein 792

2

0

High-throughput

0.580

High

624450

FOXR2
Forkhead box protein R2

2

0

High-throughput

0.580

High

624451

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.580

High

624453

ZN620
Zinc finger protein 620

2

0

High-throughput

0.580

High

624470

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.580

High

624473

ZFP90
Zinc finger protein 90 homolog

2

0

High-throughput

0.580

High

624484

NRBF2
Nuclear receptor-binding factor 2

2

0

High-throughput

0.580

High

624495

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.580

High

624496

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

624502

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

624514

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

2

0

High-throughput

0.580

High

624524

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

0

High-throughput

0.580

High

624529

SRTD3
SERTA domain-containing protein 3

2

0

High-throughput

0.580

High

624532

ISY1
Pre-mRNA-splicing factor ISY1 homolog

2

0

High-throughput

0.580

High

624534

FA50B
Protein FAM50B

2

0

High-throughput

0.580

High

624465

HACE1
E3 ubiquitin-protein ligase HACE1

1

5

Small-scale

0.578

High

531446

K1C13
Keratin, type I cytoskeletal 13

2

7

High-throughput

0.576

High

178948

FOXP2
Forkhead box protein P2

1

4

High-throughput

0.573

High

579992

K1C15
Keratin, type I cytoskeletal 15

1

6

High-throughput

0.573

High

624526

PUF60
Poly(U)-binding-splicing factor PUF60

1

4

High-throughput

0.573

High

280528

KRT34
Keratin, type I cuticular Ha4

2

7

High-throughput

0.553

High

624459

K1C27
Keratin, type I cytoskeletal 27

2

7

High-throughput

0.553

High

624462

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

624477

SHC3
SHC-transforming protein 3

2

6

High-throughput

0.553

High

624487

RBM41
RNA-binding protein 41

2

3

High-throughput

0.553

High

624489

CFA53
Cilia- and flagella-associated protein 53

2

1

High-throughput

0.553

High

624504

BTBD2
BTB/POZ domain-containing protein 2

2

1

High-throughput

0.553

High

624533

T3JAM
TRAF3-interacting JNK-activating modulator

2

3

High-throughput

0.553

High

267621

TADA3
Transcriptional adapter 3

1

0

High-throughput

0.549

High

624440

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.549

High

624516

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.549

High

388232

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.541

High

344276

AACT
Alpha-1-antichymotrypsin

1

6

High-throughput

0.536

High

416353

S10A9
Protein S100-A9

1

6

High-throughput

0.536

High

596250

FILA
Filaggrin

1

4

High-throughput

0.536

High

624398

S100P
Protein S100-P

1

6

High-throughput

0.536

High

624399

SPB3
Serpin B3

1

6

High-throughput

0.536

High

624401

S10A7
Protein S100-A7

1

6

High-throughput

0.536

High

624402

CASPE
Caspase-14

1

2

High-throughput

0.536

High

624442

FILA2
Filaggrin-2

1

6

High-throughput

0.536

High

624449

FXL19
F-box/LRR-repeat protein 19

1

5

High-throughput

0.536

High

624528

SPB13
Serpin B13

1

5

High-throughput

0.536

High

624427

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.523

High

624497

LZTS2
Leucine zipper putative tumor suppressor 2

1

4

High-throughput

0.523

High

263523

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.515

High

624417

CASP6
Caspase-6

1

2

High-throughput

0.515

High

624447

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.515

High

624454

SRCAP
Helicase SRCAP

1

2

High-throughput

0.515

High

120069

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

532839

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.513

High

542998

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

546814

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

617208

LORI
Loricrin

1

0

High-throughput

0.513

High

624397

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.513

High

624409

LEG7
Galectin-7

1

0

High-throughput

0.513

High

624507

ZN350
Zinc finger protein 350

1

0

High-throughput

0.513

High

624521

IL37
Interleukin-37

1

0

High-throughput

0.513

High

584543

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

4

Small-scale

0.501

High

624412

MCM2
DNA replication licensing factor MCM2

1

6

Small-scale

0.501

High

624478

ESR2
Estrogen receptor beta

1

19

Small-scale

0.501

High

554405

GATA1
Erythroid transcription factor

1

1

Small-scale

0.500

High

624408

HD
Huntingtin

1

0

High-throughput

0.493

High

624460

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

624479

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

198403

KLK10
Kallikrein-10

1

2

High-throughput

0.489

High

245789

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

271851

SPB7
Serpin B7

1

6

High-throughput

0.489

High

396318

APOD
Apolipoprotein D

1

1

High-throughput

0.489

High

453950

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

High-throughput

0.489

High

611205

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.489

High

624410

SPB4
Serpin B4

1

6

High-throughput

0.489

High

624413

KLK7
Kallikrein-7

1

1

High-throughput

0.489

High

624426

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

624461

S1A7A
Protein S100-A7A

1

6

High-throughput

0.489

High

624464

SPA12
Serpin A12

1

6

High-throughput

0.489

High

624530

DJC12
DnaJ homolog subfamily C member 12

1

3

High-throughput

0.489

High

266531

GPC4
Glypican-4

1

0

High-throughput

0.486

High

624510

P63
Tumor protein 63

1

9

High-throughput

0.481

High

226554

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

583393

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

624396

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

High-throughput

0.479

High

624400

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.479

High

624403

T2FA
General transcription factor IIF subunit 1

1

1

Small-scale

0.479

High

624404

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

3

High-throughput

0.479

High

624428

TP53B
TP53-binding protein 1

1

3

High-throughput

0.479

High

624430

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

7

Small-scale

0.479

High

624444

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

4

High-throughput

0.479

High

624481

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

49554

A1A4E9
Keratin 13

1

7

High-throughput

0.470

High

111170

I6L9F6
NEFL protein

1

4

High-throughput

0.470

High

527301

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

535328

GFAP
Glial fibrillary acidic protein

1

3

High-throughput

0.470

High

624441

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.470

High

624488

MY15B
Unconventional myosin-XVB

1

1

High-throughput

0.470

High

624536

SHLB1
Endophilin-B1

1

3

High-throughput

0.470

High

583646

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

624416

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

624431

IRF4
Interferon regulatory factor 4

1

0

Small-scale

0.458

High

624456

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

422147

NFL
Neurofilament light polypeptide

1

4

High-throughput

0.439

High

624506

TRI54
Tripartite motif-containing protein 54

1

9

High-throughput

0.439

High

146595

SOCS2
Suppressor of cytokine signaling 2

1

8

Small-scale

0.437

High

624476

LZIC
Protein LZIC

1

1

High-throughput

0.437

High

624483

MTBP
Mdm2-binding protein

1

1

Small-scale

0.437

High

624517

CISH
Cytokine-inducible SH2-containing protein

1

7

Small-scale

0.437

High

583935

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

4

0

High-throughput

0.363

High

624491

PNMA5
Paraneoplastic antigen-like protein 5

2

0

High-throughput

0.327

High

238145

PLIN3
Perilipin-3

2

0

High-throughput

0.316

High

568436

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

624438

F161A
Protein FAM161A

2

0

High-throughput

0.316

High

624467

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

624472

PKHO2
Pleckstrin homology domain-containing family O member 2

2

0

High-throughput

0.316

High

624490

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

624505

TEX12
Testis-expressed protein 12

2

0

High-throughput

0.316

High

157527

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.299

High

624475

DYDC1
DPY30 domain-containing protein 1

1

0

High-throughput

0.299

High

259829

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

572110

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

588403

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

623562

IBP6
Insulin-like growth factor-binding protein 6

1

0

High-throughput

0.279

Low

624433

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

624436

CH3L2
Chitinase-3-like protein 2

1

0

High-throughput

0.279

Low

624437

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

624443

XKR4
XK-related protein 4

1

0

High-throughput

0.279

Low

624445

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

624446

DMKN
Dermokine

1

0

High-throughput

0.279

Low

624452

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

624455

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

624466

FAM9C
Protein FAM9C

1

0

High-throughput

0.279

Low

624469

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

624474

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

624492

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

624508

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

624522

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

624527

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

47200

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

624498

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024