Protein: ID2
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)

Gene: ID2
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q02363

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000791 - euchromatin
GO:0003166 - bundle of His development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551502

TFE2
Transcription factor E2-alpha

8

20

Small-scale

0.975

High

551118

ITF2
Transcription factor 4

7

20

Small-scale

0.964

High

970599

HTF4
Transcription factor 12

7

20

Small-scale

0.962

High

970583

ASCL4
Achaete-scute homolog 4

3

20

High-throughput

0.858

High

814905

ID4
DNA-binding protein inhibitor ID-4

2

4

High-throughput

0.811

High

545958

MYOD1
Myoblast determination protein 1

2

13

Small-scale

0.800

High

63044

MSGN1
Mesogenin-1

2

19

High-throughput

0.783

High

970595

PDLI5
PDZ and LIM domain protein 5

1

2

Small-scale

0.756

High

970559

ID2
DNA-binding protein inhibitor ID-2

2

4

Small-scale

0.743

High

970589

LMO3
LIM domain only protein 3

1

4

High-throughput

0.665

High

738956

SRBP1
Sterol regulatory element-binding protein 1

1

1

Small-scale

0.647

High

632696

TYY1
Transcriptional repressor protein YY1

2

2

High-throughput

0.628

High

970592

PHF3
PHD finger protein 3

2

1

High-throughput

0.628

High

414252

RB
Retinoblastoma-associated protein

2

3

Small-scale

0.624

High

238590

MUSC
Musculin

1

11

Small-scale

0.621

High

526743

MYF5
Myogenic factor 5

1

17

Small-scale

0.621

High

970566

OLIG2
Oligodendrocyte transcription factor 2

1

15

Small-scale

0.618

High

970588

OLIG1
Oligodendrocyte transcription factor 1

1

16

Small-scale

0.618

High

501992

BIP
Endoplasmic reticulum chaperone BiP

2

2

Small-scale

0.614

High

254581

CLAP2
CLIP-associating protein 2

2

1

High-throughput

0.611

High

207307

FRS3
Fibroblast growth factor receptor substrate 3

2

1

High-throughput

0.606

High

625374

CDK2
Cyclin-dependent kinase 2

2

4

Small-scale

0.602

High

970562

RBL2
Retinoblastoma-like protein 2

2

3

Small-scale

0.584

High

970600

TCHP
Trichoplein keratin filament-binding protein

2

0

High-throughput

0.580

High

970606

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

970607

FANCL
E3 ubiquitin-protein ligase FANCL

2

0

High-throughput

0.580

High

970612

FZR1
Fizzy-related protein homolog

1

4

Small-scale

0.578

High

970590

RIN3
Ras and Rab interactor 3

2

1

High-throughput

0.576

High

771921

VHL
von Hippel-Lindau disease tumor suppressor

1

2

Small-scale

0.561

High

798864

GATA4
Transcription factor GATA-4

1

2

Small-scale

0.561

High

970568

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

Small-scale

0.561

High

970573

ELOC
Elongin-C

1

2

Small-scale

0.561

High

970616

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

6

Small-scale

0.561

High

970582

CV039
Synaptic plasticity regulator PANTS

2

1

High-throughput

0.553

High

970570

CASL
Enhancer of filamentation 1

1

3

Small-scale

0.552

High

970581

TENS2
Tensin-2

2

0

High-throughput

0.551

High

672812

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.537

High

970604

APC1
Anaphase-promoting complex subunit 1

1

0

Small-scale

0.537

High

970617

ASB4
Ankyrin repeat and SOCS box protein 4

1

0

Small-scale

0.537

High

970560

DYST
Dystonin

1

1

High-throughput

0.536

High

970601

DIDO1
Death-inducer obliterator 1

1

1

High-throughput

0.536

High

970613

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

1

High-throughput

0.536

High

970567

PKD2
Polycystin-2

1

1

Small-scale

0.529

High

970574

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

1

Small-scale

0.527

High

970564

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

970569

FCL
GDP-L-fucose synthase

1

0

High-throughput

0.518

High

970577

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

507957

FGFR1
Fibroblast growth factor receptor 1

1

1

High-throughput

0.515

High

614300

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

923647

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.515

High

970571

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

High-throughput

0.515

High

970593

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.515

High

307249

RCBT2
RCC1 and BTB domain-containing protein 2

1

0

High-throughput

0.513

High

851804

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

0

High-throughput

0.513

High

876361

AFAD
Afadin

1

0

High-throughput

0.513

High

970576

RABL6
Rab-like protein 6

1

0

High-throughput

0.513

High

970585

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

970586

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.513

High

970597

KI20B
Kinesin-like protein KIF20B

1

0

High-throughput

0.513

High

970608

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.513

High

970609

RBM27
RNA-binding protein 27

1

0

High-throughput

0.513

High

970610

CFDP1
Craniofacial development protein 1

1

0

High-throughput

0.513

High

970614

KLH20
Kelch-like protein 20

1

0

High-throughput

0.513

High

970615

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.513

High

203669

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

2

High-throughput

0.508

High

647546

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.508

High

658895

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.508

High

970596

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.508

High

970605

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

2

High-throughput

0.508

High

414873

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.501

High

203916

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

566360

KPCA
Protein kinase C alpha type

1

0

High-throughput

0.493

High

791494

HD
Huntingtin

1

0

High-throughput

0.493

High

904458

1433G
14-3-3 protein gamma

1

0

High-throughput

0.493

High

970563

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.493

High

232110

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

800751

MK08
Mitogen-activated protein kinase 8

1

4

High-throughput

0.481

High

970584

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.480

High

970611

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.480

High

153647

ANM5
Protein arginine N-methyltransferase 5

1

1

Small-scale

0.479

High

296293

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

3

Small-scale

0.479

High

428149

TBB5
Tubulin beta chain

1

1

Small-scale

0.479

High

503925

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.479

High

660119

RBL1
Retinoblastoma-like protein 1

1

3

Small-scale

0.479

High

713947

HS71L
Heat shock 70 kDa protein 1-like

1

1

Small-scale

0.479

High

751585

GRP75
Stress-70 protein, mitochondrial

1

3

Small-scale

0.479

High

858090

NKX25
Homeobox protein Nkx-2.5

1

2

Small-scale

0.479

High

882250

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

Small-scale

0.479

High

933176

TBA1B
Tubulin alpha-1B chain

1

2

Small-scale

0.479

High

933763

TBB4B
Tubulin beta-4B chain

1

1

Small-scale

0.479

High

970565

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

970575

E2F4
Transcription factor E2F4

1

1

Small-scale

0.479

High

970579

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

182707

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

Small-scale

0.458

High

310147

CCDB1
Cyclin-D1-binding protein 1

1

0

Small-scale

0.458

High

970561

EF1A2
Elongation factor 1-alpha 2

1

0

Small-scale

0.458

High

970572

STK38
Serine/threonine-protein kinase 38

1

0

Small-scale

0.458

High

970591

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

970594

ELP4
Elongator complex protein 4

1

0

Small-scale

0.458

High

970598

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.458

High

91246

E3W994
Cytoplasmic linker associated protein 2

1

1

High-throughput

0.445

High

970580

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

970602

FND11
Fibronectin type III domain-containing protein 11

2

0

High-throughput

0.316

High

970603

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

970587

CA131
Uncharacterized protein C1orf131

1

0

High-throughput

0.279

Low

47211

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

970578

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024