Protein: UPAR
Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87)

Gene: UPAR, PLAUR
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q03405

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005788 - endoplasmic reticulum lumen
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341499

UROK
Urokinase-type plasminogen activator

6

0

Small-scale

0.895

High

314814

LARG1
Xylosyl- and glucuronyltransferase LARGE1

3

1

High-throughput

0.667

High

546605

ARSA
Arylsulfatase A

3

4

High-throughput

0.667

High

550463

ARSB
Arylsulfatase B

3

4

High-throughput

0.667

High

709246

GALNS
N-acetylgalactosamine-6-sulfatase

3

4

High-throughput

0.667

High

856916

NDST2
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

3

1

High-throughput

0.667

High

976221

MA2A1
Alpha-mannosidase 2

3

1

High-throughput

0.667

High

976223

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

3

1

High-throughput

0.667

High

976229

ARSK
Arylsulfatase K

3

4

High-throughput

0.667

High

976237

CHSS1
Chondroitin sulfate synthase 1

3

1

High-throughput

0.667

High

976242

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

3

1

High-throughput

0.667

High

976249

PCSK5
Proprotein convertase subtilisin/kexin type 5

3

1

High-throughput

0.667

High

708141

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

3

0

High-throughput

0.638

High

877403

LAMB2
Laminin subunit beta-2

3

0

High-throughput

0.638

High

976206

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

3

0

High-throughput

0.638

High

976207

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

3

0

High-throughput

0.638

High

976211

MELK
Maternal embryonic leucine zipper kinase

3

0

High-throughput

0.638

High

976218

EXT1
Exostosin-1

3

0

High-throughput

0.638

High

976219

PKN1
Serine/threonine-protein kinase N1

3

0

High-throughput

0.638

High

976244

PGLT1
Protein O-glucosyltransferase 1

3

0

High-throughput

0.638

High

976246

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

3

0

High-throughput

0.638

High

976248

PXDN
Peroxidasin homolog

3

0

High-throughput

0.638

High

976254

DHRS4
Dehydrogenase/reductase SDR family member 4

3

0

High-throughput

0.638

High

976260

MCM9
DNA helicase MCM9

3

0

High-throughput

0.638

High

976262

DNJB9
DnaJ homolog subfamily B member 9

3

0

High-throughput

0.638

High

976268

LOXL2
Lysyl oxidase homolog 2

3

0

High-throughput

0.638

High

976212

MBTP1
Membrane-bound transcription factor site-1 protease

2

1

High-throughput

0.611

High

976259

EMIL3
EMILIN-3

2

1

High-throughput

0.611

High

830072

MA2A2
Alpha-mannosidase 2x

3

1

High-throughput

0.609

High

849835

SPHM
N-sulphoglucosamine sulphohydrolase

3

4

High-throughput

0.609

High

856903

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

3

1

High-throughput

0.609

High

976231

CHSS3
Chondroitin sulfate synthase 3

3

1

High-throughput

0.609

High

976240

LARG2
Xylosyl- and glucuronyltransferase LARGE2

3

1

High-throughput

0.609

High

976252

DDX11
ATP-dependent DNA helicase DDX11

3

1

High-throughput

0.609

High

433713

LYN
Tyrosine-protein kinase Lyn

2

2

Small-scale

0.601

High

976255

TX101
Testis-expressed protein 101

1

0

Small-scale

0.586

High

874436

PLTP
Phospholipid transfer protein

2

0

High-throughput

0.585

High

396625

ITB2
Integrin beta-2

2

0

Small-scale

0.559

High

976264

PCYOX
Prenylcysteine oxidase 1

2

1

High-throughput

0.558

High

209229

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.546

High

976205

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

Small-scale

0.537

High

574198

BMP7
Bone morphogenetic protein 7

1

1

High-throughput

0.536

High

933410

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.536

High

976256

CST11
Cystatin-11

1

2

High-throughput

0.536

High

932661

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

616798

JAK1
Tyrosine-protein kinase JAK1

1

4

Small-scale

0.515

High

669162

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

4

Small-scale

0.515

High

557375

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

931518

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.513

High

968820

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

976251

CTHR1
Collagen triple helix repeat-containing protein 1

1

0

High-throughput

0.513

High

976257

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

976261

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.513

High

345184

KNG1
Kininogen-1

1

2

Small-scale

0.501

High

47213

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

413892

GELS
Gelsolin

1

0

High-throughput

0.493

High

868151

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

976234

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

713409

BMP8B
Bone morphogenetic protein 8B

1

1

High-throughput

0.489

High

358744

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

506110

ITAM
Integrin alpha-M

1

0

Small-scale

0.480

High

514825

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

Small-scale

0.480

High

976208

SEPR
Prolyl endopeptidase FAP

1

0

Small-scale

0.480

High

371404

ANGI
Angiogenin

1

0

Small-scale

0.479

High

442811

HCK
Tyrosine-protein kinase HCK

1

2

Small-scale

0.479

High

454824

FGR
Tyrosine-protein kinase Fgr

1

2

Small-scale

0.479

High

976232

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.479

High

976245

PCYXL
Prenylcysteine oxidase-like

1

1

High-throughput

0.479

High

205294

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

346580

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

445755

5HT1A
5-hydroxytryptamine receptor 1A

1

0

Small-scale

0.458

High

819447

CD151
CD151 antigen

1

0

Small-scale

0.458

High

969629

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

976214

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

976215

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

976225

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.458

High

976241

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

Small-scale

0.458

High

976243

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

976263

EGFL7
Epidermal growth factor-like protein 7

1

0

High-throughput

0.458

High

976217

SURF2
Surfeit locus protein 2

1

0

High-throughput

0.438

High

344971

CYTN
Cystatin-SN

1

2

Small-scale

0.437

High

976253

CNT3B
Contactin-associated protein-like 3B

1

0

High-throughput

0.426

High

66876

D11L8
Putative ATP-dependent RNA helicase DDX11-like protein 8

1

1

High-throughput

0.407

High

207039

XRCC3
DNA repair protein XRCC3

3

0

High-throughput

0.347

High

245896

HUS1
Checkpoint protein HUS1

3

0

High-throughput

0.347

High

851463

NEK4
Serine/threonine-protein kinase Nek4

3

0

High-throughput

0.347

High

976204

UBE3A
Ubiquitin-protein ligase E3A

3

0

High-throughput

0.347

High

976209

TBB3
Tubulin beta-3 chain

3

0

High-throughput

0.347

High

976220

TAZ
Tafazzin

3

0

High-throughput

0.347

High

976222

FUT11
Alpha-(1,3)-fucosyltransferase 11

3

0

High-throughput

0.347

High

976226

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

3

0

High-throughput

0.347

High

976235

ADCK1
AarF domain-containing protein kinase 1

3

0

High-throughput

0.347

High

976238

DYR2
Dihydrofolate reductase 2, mitochondrial

3

0

High-throughput

0.347

High

976239

P3H3
Prolyl 3-hydroxylase 3

3

0

High-throughput

0.347

High

976250

TATD2
Putative deoxyribonuclease TATDN2

3

0

High-throughput

0.347

High

976266

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

3

0

High-throughput

0.347

High

973314

TOP2B
DNA topoisomerase 2-beta

2

0

High-throughput

0.328

High

622783

COT2
COUP transcription factor 2

2

0

High-throughput

0.318

High

723687

HXD13
Homeobox protein Hox-D13

2

0

High-throughput

0.318

High

819408

GSH0
Glutamate--cysteine ligase regulatory subunit

2

0

High-throughput

0.318

High

872932

ANAG
Alpha-N-acetylglucosaminidase

2

0

High-throughput

0.318

High

976224

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

2

0

High-throughput

0.318

High

976227

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

2

0

High-throughput

0.318

High

976233

TRM11
tRNA

2

0

High-throughput

0.318

High

976265

NOCT
Nocturnin

2

0

High-throughput

0.318

High

714956

PROF2
Profilin-2

1

0

High-throughput

0.282

High

976210

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.282

High

167225

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.249

Low

575387

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

738747

SPB5
Serpin B5

1

0

Small-scale

0.249

Low

838564

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.249

Low

846684

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

0

High-throughput

0.249

Low

961367

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

0

Small-scale

0.249

Low

976213

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low

976216

OZF
Zinc finger protein OZF

1

0

High-throughput

0.249

Low

976228

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

976230

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

976236

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.249

Low

976247

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

Small-scale

0.249

Low

976258

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low

976267

CDYL
Chromodomain Y-like protein

1

0

High-throughput

0.249

Low

902538

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024