Protein: OTU7B
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)

Gene: OTU7B, OTUD7B
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q6GQQ9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001701 - in utero embryonic development
GO:0002250 - adaptive immune response
GO:0002385 - mucosal immune response
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475915

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

14

11

Small-scale

0.983

High

1151619

OTU7A
OTU domain-containing protein 7A

2

4

Small-scale

0.789

High

475060

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

11

Small-scale

0.759

High

1151635

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

5

5

Small-scale

0.716

High

160626

AURKA
Aurora kinase A

3

6

Small-scale

0.674

High

227767

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.665

High

803581

BAG6
Large proline-rich protein BAG6

1

10

High-throughput

0.665

High

1151639

UBQL1
Ubiquilin-1

1

7

High-throughput

0.665

High

1086904

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

7

Small-scale

0.647

High

1151622

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

3

High-throughput

0.634

High

125519

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

6

Small-scale

0.611

High

1151618

TNIP2
TNFAIP3-interacting protein 2

2

2

Small-scale

0.606

High

594562

PSB1
Proteasome subunit beta type-1

2

10

High-throughput

0.606

High

1151608

EPMIP
EPM2A-interacting protein 1

2

2

High-throughput

0.606

High

1151616

SPART
Spartin

2

6

High-throughput

0.606

High

1151625

HSFY1
Heat shock transcription factor, Y-linked

2

1

High-throughput

0.606

High

1151633

CDIP1
Cell death-inducing p53-target protein 1

2

2

High-throughput

0.606

High

1036660

SQSTM
Sequestosome-1

2

6

Small-scale

0.584

High

1065111

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

1151610

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.580

High

1151624

OTUL
Ubiquitin thioesterase otulin

2

0

High-throughput

0.580

High

538561

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.578

High

369809

ESR1
Estrogen receptor

1

2

Small-scale

0.561

High

818153

SOX2
Transcription factor SOX-2

1

4

Small-scale

0.561

High

1017395

CDC20
Cell division cycle protein 20 homolog

1

5

Small-scale

0.561

High

1151617

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

Small-scale

0.561

High

1151638

FZR1
Fizzy-related protein homolog

1

4

Small-scale

0.561

High

1151623

TANK
TRAF family member-associated NF-kappa-B activator

1

1

High-throughput

0.536

High

1151627

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.534

High

1151615

CCD50
Coiled-coil domain-containing protein 50

1

2

Small-scale

0.529

High

273843

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.515

High

1075418

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

10

High-throughput

0.515

High

1151634

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

6

High-throughput

0.515

High

1151641

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.515

High

157924

KLF11
Krueppel-like factor 11

1

12

High-throughput

0.515

High

203962

HTRA2
Serine protease HTRA2, mitochondrial

1

2

High-throughput

0.515

High

265531

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

4

High-throughput

0.515

High

281681

WFS1
Wolframin

1

1

High-throughput

0.515

High

336524

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.515

High

363821

ALBU
Albumin

1

3

High-throughput

0.515

High

388513

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.515

High

413953

GELS
Gelsolin

1

4

High-throughput

0.515

High

448127

DOPO
Dopamine beta-hydroxylase

1

1

High-throughput

0.515

High

535427

GFAP
Glial fibrillary acidic protein

1

5

High-throughput

0.515

High

647609

MK03
Mitogen-activated protein kinase 3

1

3

High-throughput

0.515

High

719521

MERL
Merlin

1

9

High-throughput

0.515

High

742351

SYUA
Alpha-synuclein

1

1

High-throughput

0.515

High

780723

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

5

High-throughput

0.515

High

848054

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.515

High

871617

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.515

High

877066

CASP6
Caspase-6

1

6

High-throughput

0.515

High

893379

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

4

High-throughput

0.515

High

919124

RAN
GTP-binding nuclear protein Ran

1

8

High-throughput

0.515

High

1025791

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.515

High

1051324

DCTN1
Dynactin subunit 1

1

10

High-throughput

0.515

High

1151611

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

1151640

RNF11
RING finger protein 11

1

4

High-throughput

0.515

High

1151614

ZDH17
Palmitoyltransferase ZDHHC17

1

12

High-throughput

0.494

High

151311

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.493

High

156671

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

High-throughput

0.493

High

868548

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

1151607

MTSS2
Protein MTSS 2

1

4

High-throughput

0.489

High

232245

KDM1A
Lysine-specific histone demethylase 1A

1

4

Small-scale

0.479

High

262281

ULK1
Serine/threonine-protein kinase ULK1

1

7

Small-scale

0.479

High

338556

EGFR
Epidermal growth factor receptor

1

3

Small-scale

0.479

High

347048

MYC
Myc proto-oncogene protein

1

3

Small-scale

0.479

High

717159

CTNB1
Catenin beta-1

1

8

Small-scale

0.479

High

776134

ARL1
ADP-ribosylation factor-like protein 1

1

7

High-throughput

0.479

High

779592

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

804268

NOTC1
Neurogenic locus notch homolog protein 1

1

10

Small-scale

0.479

High

808692

YAP1
Transcriptional coactivator YAP1

1

8

Small-scale

0.479

High

993323

FOXM1
Forkhead box protein M1

1

5

Small-scale

0.479

High

1024691

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

1041801

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1054148

BECN1
Beclin-1

1

1

Small-scale

0.479

High

1056425

IRF3
Interferon regulatory factor 3

1

3

Small-scale

0.479

High

1059309

CASP8
Caspase-8

1

6

Small-scale

0.479

High

1085589

HIF1A
Hypoxia-inducible factor 1-alpha

1

2

Small-scale

0.479

High

1151606

ANO7
Anoctamin-7

1

1

Small-scale

0.479

High

1151612

TAXB1
Tax1-binding protein 1

1

11

Small-scale

0.479

High

1151628

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

9

Small-scale

0.479

High

1151629

EPAS1
Endothelial PAS domain-containing protein 1

1

2

Small-scale

0.479

High

1151630

LST8
Target of rapamycin complex subunit LST8

1

4

Small-scale

0.479

High

1151636

RHBL2
Rhomboid-related protein 2

1

1

Small-scale

0.479

High

1151637

WWOX
WW domain-containing oxidoreductase

1

3

High-throughput

0.479

High

103756

G5E9A7
DM1 locus, WD repeat containing

1

6

High-throughput

0.470

High

231563

KIF1B
Kinesin-like protein KIF1B

1

8

High-throughput

0.470

High

263679

PR40A
Pre-mRNA-processing factor 40 homolog A

1

13

High-throughput

0.470

High

344505

A2MG
Alpha-2-macroglobulin

1

5

High-throughput

0.470

High

363606

TTHY
Transthyretin

1

1

High-throughput

0.470

High

527535

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

583990

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.470

High

609351

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.470

High

1012406

Q0VDC6
peptidylprolyl isomerase

1

5

High-throughput

0.470

High

1060456

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

2

High-throughput

0.470

High

1151631

NUP58
Nucleoporin p58/p45

1

2

High-throughput

0.470

High

254406

N4BP1
NEDD4-binding protein 1

1

0

Small-scale

0.458

High

816510

MAOX
NADP-dependent malic enzyme

1

0

Small-scale

0.458

High

683442

1433B
14-3-3 protein beta/alpha

1

19

Small-scale

0.457

High

121496

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

7

Small-scale

0.445

High

1151626

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

9

High-throughput

0.445

High

435672

IGF1R
Insulin-like growth factor 1 receptor

1

3

Small-scale

0.437

High

584420

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

7

Small-scale

0.437

High

1151609

MAVS
Mitochondrial antiviral-signaling protein

1

8

Small-scale

0.437

High

1151621

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

47237

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

1151613

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

1151620

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1151642

Q9Y649
GW128

1

0

High-throughput

0.268

Low

100861

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1151632

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024