Protein: PPR21
Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (Ferry endosomal RAB5 effector complex subunit 2) (Fy-2) (KLRAQ motif-containing protein 1)

Gene: PPR21, PPP1R21
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q6ZMI0

Gene Ontology (top 5):
GO:0005769 - early endosome
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1168325

FERY3
Ferry endosomal RAB5 effector complex subunit 3

2

0

High-throughput

0.602

High

324955

QORL1
Quinone oxidoreductase-like protein 1

2

0

High-throughput

0.585

High

1121472

KLH26
Kelch-like protein 26

2

1

High-throughput

0.574

High

1164610

KLH24
Kelch-like protein 24

2

1

High-throughput

0.574

High

1168306

KBTB6
Kelch repeat and BTB domain-containing protein 6

2

3

High-throughput

0.574

High

1168314

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

2

High-throughput

0.574

High

1168318

BTBD9
BTB/POZ domain-containing protein 9

2

2

High-throughput

0.574

High

647614

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.536

High

658978

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.536

High

930894

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

High-throughput

0.536

High

529307

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

1168332

SHLB1
Endophilin-B1

1

1

High-throughput

0.515

High

764392

FEN1
Flap endonuclease 1

1

0

High-throughput

0.513

High

770615

TXLNA
Alpha-taxilin

1

0

High-throughput

0.513

High

1168323

RABE2
Rab GTPase-binding effector protein 2

1

0

High-throughput

0.513

High

1168326

BIRC6
Baculoviral IAP repeat-containing protein 6

1

0

High-throughput

0.513

High

1168336

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.513

High

1168319

SH3G2
Endophilin-A1

1

1

High-throughput

0.508

High

47247

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

203969

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.493

High

263686

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

527554

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

791686

HD
Huntingtin

1

0

High-throughput

0.493

High

803599

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.493

High

919134

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.493

High

1168315

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

297511

TOX4
TOX high mobility group box family member 4

1

1

High-throughput

0.489

High

1041370

CUL2
Cullin-2

1

1

High-throughput

0.489

High

525968

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

592330

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.479

High

1168304

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

905978

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.457

High

965724

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1043070

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

1131741

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.437

High

497207

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.407

High

445721

IL6RA
Interleukin-6 receptor subunit alpha

2

0

High-throughput

0.328

High

723650

TSP2
Thrombospondin-2

2

0

High-throughput

0.328

High

1168309

FXL14
F-box/LRR-repeat protein 14

2

0

High-throughput

0.328

High

1168310

WDTC1
WD and tetratricopeptide repeats protein 1

2

0

High-throughput

0.328

High

1168312

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.328

High

1168322

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

2

0

High-throughput

0.328

High

1168324

SH22A
SH2 domain-containing protein 2A

2

0

High-throughput

0.310

High

1168308

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

152659

KMT2D
Histone-lysine N-methyltransferase 2D

1

0

High-throughput

0.279

Low

235185

STX10
Syntaxin-10

1

0

High-throughput

0.279

Low

664241

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.279

Low

836242

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.279

Low

873440

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.279

Low

959172

METK1
S-adenosylmethionine synthase isoform type-1

1

0

High-throughput

0.279

Low

975189

ACY1
Aminoacylase-1

1

0

High-throughput

0.279

Low

989327

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.279

Low

1027873

MYBPH
Myosin-binding protein H

1

0

High-throughput

0.279

Low

1135930

CE162
Centrosomal protein of 162 kDa

1

0

High-throughput

0.279

Low

1153027

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.279

Low

1168307

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

0

High-throughput

0.279

Low

1168311

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.279

Low

1168313

TBCK
TBC domain-containing protein kinase-like protein

1

0

High-throughput

0.279

Low

1168321

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.279

Low

1168328

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.279

Low

1168329

IMPCT
Protein IMPACT

1

0

High-throughput

0.279

Low

1168331

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.279

Low

1168333

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.279

Low

671843

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.269

Low

151315

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

157936

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

336932

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.268

Low

358806

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.268

Low

413151

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

413964

GELS
Gelsolin

1

0

High-throughput

0.268

Low

535436

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.268

Low

583998

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

609370

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

667700

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.268

Low

868560

ATX1
Ataxin-1

1

0

High-throughput

0.268

Low

877075

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

958467

CYC
Cytochrome c

1

0

High-throughput

0.268

Low

1025803

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

1060461

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

1168305

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

1168317

KLK6
Kallikrein-6

1

0

High-throughput

0.268

Low

1168320

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

825712

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

1168334

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

205568

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

882377

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1103935

ZN750
Zinc finger protein 750

1

0

Small-scale

0.249

Low

1158364

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.249

Low

1168303

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1168316

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.249

Low

1168330

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1168335

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

1168327

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

110851

H7C417
CRAL-TRIO domain-containing protein

1

0

High-throughput

0.232

Low

120950

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.232

Low

1091124

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024