Protein: HYPK
Huntingtin-interacting protein K (Huntingtin yeast partner K)

Gene: HYPK
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q9NX55

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0015630 - microtubule cytoskeleton
GO:0032991 - protein-containing complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315331

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

8

2

Small-scale

0.753

High

782303

NAA10
N-alpha-acetyltransferase 10

4

4

Small-scale

0.702

High

792030

HD
Huntingtin

4

0

Small-scale

0.653

High

770696

TXLNA
Alpha-taxilin

3

0

High-throughput

0.646

High

1154525

NAA16
N-alpha-acetyltransferase 16, NatA auxiliary subunit

2

2

High-throughput

0.628

High

888223

TPIS
Triosephosphate isomerase

2

0

Small-scale

0.585

High

395911

A4
Amyloid-beta precursor protein

2

0

Small-scale

0.569

High

1306274

MDFI
MyoD family inhibitor

2

0

Small-scale

0.561

High

1309869

RHXF2
Rhox homeobox family member 2

2

0

Small-scale

0.561

High

795680

MAGA1
Melanoma-associated antigen 1

1

0

High-throughput

0.549

High

1079614

NEDD8
NEDD8

1

0

Small-scale

0.537

High

1311635

NAA11
N-alpha-acetyltransferase 11

1

4

High-throughput

0.536

High

1326932

NAA50
N-alpha-acetyltransferase 50

1

4

High-throughput

0.536

High

361404

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

391934

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.513

High

1347770

YETS2
YEATS domain-containing protein 2

1

0

High-throughput

0.513

High

1326182

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

Small-scale

0.512

High

1198345

ALPK2
Alpha-protein kinase 2

1

1

High-throughput

0.489

High

970903

SP4
Transcription factor Sp4

1

1

High-throughput

0.481

High

166791

CE290
Centrosomal protein of 290 kDa

1

1

Small-scale

0.479

High

335209

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

Small-scale

0.479

High

751861

GRP75
Stress-70 protein, mitochondrial

1

1

Small-scale

0.479

High

885616

MLF1
Myeloid leukemia factor 1

1

1

Small-scale

0.479

High

891341

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

Small-scale

0.479

High

1012524

HSP7E
Heat shock 70 kDa protein 14

1

1

Small-scale

0.479

High

1051484

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1078364

MLF2
Myeloid leukemia factor 2

1

1

Small-scale

0.479

High

1304429

DNJC2
DnaJ homolog subfamily C member 2

1

1

Small-scale

0.479

High

308138

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.460

High

855235

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

0

High-throughput

0.460

High

931901

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.460

High

1072042

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.460

High

1238783

BOLL
Protein boule-like

1

0

High-throughput

0.460

High

1242738

PHC3
Polyhomeotic-like protein 3

1

0

High-throughput

0.460

High

1294578

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.460

High

1346926

THAP1
THAP domain-containing protein 1

1

0

High-throughput

0.460

High

1347162

RFOX1
RNA binding protein fox-1 homolog 1

1

0

High-throughput

0.460

High

254418

N4BP1
NEDD4-binding protein 1

1

0

Small-scale

0.458

High

257228

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

0

Small-scale

0.458

High

299477

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

364028

VTDB
Vitamin D-binding protein

1

0

Small-scale

0.458

High

387614

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

388761

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.458

High

438567

HS90B
Heat shock protein HSP 90-beta

1

0

Small-scale

0.458

High

443846

VIME
Vimentin

1

0

Small-scale

0.458

High

504856

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.458

High

527840

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

Small-scale

0.458

High

570119

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

575200

RL7
Large ribosomal subunit protein uL30

1

0

Small-scale

0.458

High

578364

PGAM1
Phosphoglycerate mutase 1

1

0

Small-scale

0.458

High

607730

NDKB
Nucleoside diphosphate kinase B

1

0

Small-scale

0.458

High

653749

CALR
Calreticulin

1

0

Small-scale

0.458

High

728521

MYH11
Myosin-11

1

0

High-throughput

0.458

High

871488

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

0

High-throughput

0.458

High

877548

CAD11
Cadherin-11

1

0

Small-scale

0.458

High

899062

PSME3
Proteasome activator complex subunit 3

1

0

Small-scale

0.458

High

932895

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.458

High

961293

HSF1
Heat shock factor protein 1

1

0

Small-scale

0.458

High

978914

TF65
Transcription factor p65

1

0

Small-scale

0.458

High

1018718

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

Small-scale

0.458

High

1045368

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

1054215

BECN1
Beclin-1

1

0

Small-scale

0.458

High

1058832

LBR
Delta(14)-sterol reductase LBR

1

0

Small-scale

0.458

High

1064778

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1220577

NELFD
Negative elongation factor C/D

1

0

Small-scale

0.458

High

1223399

ZN100
Zinc finger protein 100

1

0

Small-scale

0.458

High

1268303

ZN516
Zinc finger protein 516

1

0

Small-scale

0.458

High

1274262

RBPMS
RNA-binding protein with multiple splicing

1

0

Small-scale

0.458

High

1295384

ZN462
Zinc finger protein 462

1

0

Small-scale

0.458

High

1299692

QKI
KH domain-containing RNA-binding protein QKI

1

0

Small-scale

0.458

High

1299866

LENG8
Leukocyte receptor cluster member 8

1

0

Small-scale

0.458

High

1300216

KI20B
Kinesin-like protein KIF20B

1

0

Small-scale

0.458

High

1315607

SRRT
Serrate RNA effector molecule homolog

1

0

Small-scale

0.458

High

1317357

KRA33
Keratin-associated protein 3-3

1

1

High-throughput

0.439

High

1317366

KRA32
Keratin-associated protein 3-2

1

1

High-throughput

0.439

High

828167

DHE4
Glutamate dehydrogenase 2, mitochondrial

1

1

Small-scale

0.437

High

975748

LMNB2
Lamin-B2

1

1

Small-scale

0.437

High

1328046

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

Small-scale

0.437

High

1330645

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

3

Small-scale

0.437

High

47480

RPSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.426

High

1110220

T10IP
Testis-specific protein 10-interacting protein

3

0

High-throughput

0.347

High

1102083

CB068
UPF0561 protein C2orf68

2

0

High-throughput

0.316

High

879722

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.279

Low

67378

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.251

Low

887435

KR122
Keratin-associated protein 12-2

1

0

High-throughput

0.251

Low

953135

PR20A
Proline-rich protein 20A

1

0

High-throughput

0.251

Low

1109478

KR195
Keratin-associated protein 19-5

1

0

High-throughput

0.251

Low

1216055

KRA81
Keratin-associated protein 8-1

1

0

High-throughput

0.251

Low

239621

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

744475

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.249

Low

819034

COPD
Coatomer subunit delta

1

0

Small-scale

0.249

Low

1138250

MYOM3
Myomesin-3

1

0

Small-scale

0.249

Low

1174436

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

Small-scale

0.249

Low

1262563

DNJB3
DnaJ homolog subfamily B member 3

1

0

Small-scale

0.249

Low

1274321

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

0

High-throughput

0.249

Low

1335303

VPP4
V-type proton ATPase 116 kDa subunit a 4

1

0

Small-scale

0.249

Low

353898

IGHG4
Immunoglobulin heavy constant gamma 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024