Protein: SPAST
Spastin (EC 5.6.1.1) (Spastic paraplegia 4 protein)

Gene: SPAST
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9UBP0

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000922 - spindle pole
GO:0001578 - microtubule bundle formation
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1342438

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

5

High-throughput

0.691

High

867072

IST1
IST1 homolog

3

8

Small-scale

0.674

High

858063

NUP98
Nuclear pore complex protein Nup98-Nup96

2

7

High-throughput

0.628

High

884802

NU107
Nuclear pore complex protein Nup107

2

2

High-throughput

0.628

High

1244544

NUP43
Nucleoporin Nup43

2

16

High-throughput

0.628

High

1354197

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

2

17

High-throughput

0.628

High

1330872

Q9H4D1
Protein kinase

1

9

High-throughput

0.621

High

398127

ISG15
Ubiquitin-like protein ISG15

1

20

Small-scale

0.618

High

875390

TERA
Transitional endoplasmic reticulum ATPase

1

19

High-throughput

0.618

High

1260357

NU133
Nuclear pore complex protein Nup133

2

0

High-throughput

0.602

High

1314359

NUP85
Nuclear pore complex protein Nup85

2

0

High-throughput

0.602

High

883662

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

9

High-throughput

0.590

High

1354193

FXL17
F-box/LRR-repeat protein 17

1

3

Small-scale

0.578

High

1263640

ATLA1
Atlastin-1

1

6

Small-scale

0.573

High

208865

CHM2A
Charged multivesicular body protein 2a

1

19

High-throughput

0.536

High

363934

ALBU
Albumin

1

1

High-throughput

0.536

High

451589

CLCA
Clathrin light chain A

1

5

High-throughput

0.536

High

506276

PYGM
Glycogen phosphorylase, muscle form

1

2

High-throughput

0.536

High

548339

FOSL2
Fos-related antigen 2

1

5

High-throughput

0.536

High

813809

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

905215

1433G
14-3-3 protein gamma

1

11

High-throughput

0.536

High

982584

1433F
14-3-3 protein eta

1

11

High-throughput

0.536

High

1079464

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.536

High

1169197

RN111
E3 ubiquitin-protein ligase Arkadia

1

7

High-throughput

0.536

High

1216277

H2A2B
Histone H2A type 2-B

1

3

High-throughput

0.536

High

1229795

PGAM4
Probable phosphoglycerate mutase 4

1

3

High-throughput

0.536

High

1263572

PSPC1
Paraspeckle component 1

1

9

High-throughput

0.536

High

1299039

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

5

High-throughput

0.536

High

1330534

CHM4B
Charged multivesicular body protein 4b

1

14

High-throughput

0.536

High

1354195

PLAL2
Zinc finger protein PLAGL2

1

2

High-throughput

0.536

High

1185555

CHM1B
Charged multivesicular body protein 1b

1

20

Small-scale

0.527

High

313899

SVIL
Supervillin

1

3

High-throughput

0.515

High

647468

IF
Cobalamin binding intrinsic factor

1

0

High-throughput

0.513

High

908195

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

951916

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

1015962

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.513

High

175278

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

12

High-throughput

0.501

High

934535

CSK21
Casein kinase II subunit alpha

1

5

Small-scale

0.501

High

1135851

DCAF8
DDB1- and CUL4-associated factor 8

1

11

Small-scale

0.501

High

1354196

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

11

Small-scale

0.501

High

563809

ZNF30
Zinc finger protein 30

1

0

High-throughput

0.493

High

949069

HTRA4
Serine protease HTRA4

1

4

High-throughput

0.489

High

382169

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.479

High

742578

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

929091

SKP1
S-phase kinase-associated protein 1

1

2

Small-scale

0.479

High

931917

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.479

High

1038077

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.479

High

1041244

CUL1
Cullin-1

1

16

Small-scale

0.479

High

1172103

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.479

High

1331527

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

1350491

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.479

High

1354194

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1133406

ZFY27
Protrudin

1

0

Small-scale

0.458

High

47487

RPSA2
Small ribosomal subunit protein uS2B

1

4

High-throughput

0.445

High

101251

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

831758

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.408

High

180608

TEX28
Testis-specific protein TEX28

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024