Protein: EIF3I
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)

Gene: EIF3I
Organism: Homo sapiens
Interactions: 227
UniProt ID: Q13347

Gene Ontology (top 5):
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0002183 - cytoplasmic translational initiation
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

879240

EIF3B
Eukaryotic translation initiation factor 3 subunit B

12

19

Small-scale

0.979

High

275863

EIF3G
Eukaryotic translation initiation factor 3 subunit G

10

5

Small-scale

0.973

High

176775

EIF3D
Eukaryotic translation initiation factor 3 subunit D

7

2

Small-scale

0.963

High

892792

IF4A1
Eukaryotic initiation factor 4A-I

4

11

High-throughput

0.903

High

1032102

DCA10
DDB1- and CUL4-associated factor 10

3

17

High-throughput

0.770

High

1032088

IF4A2
Eukaryotic initiation factor 4A-II

2

14

High-throughput

0.754

High

1032087

EIF3A
Eukaryotic translation initiation factor 3 subunit A

8

20

Small-scale

0.749

High

177015

EIF3H
Eukaryotic translation initiation factor 3 subunit H

7

8

Small-scale

0.747

High

888356

EIF3E
Eukaryotic translation initiation factor 3 subunit E

6

3

Small-scale

0.733

High

1032114

EIF3M
Eukaryotic translation initiation factor 3 subunit M

6

2

Small-scale

0.733

High

979890

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

6

5

Small-scale

0.730

High

1032144

EIF3C
Eukaryotic translation initiation factor 3 subunit C

5

3

High-throughput

0.718

High

1032179

EIF3L
Eukaryotic translation initiation factor 3 subunit L

5

1

High-throughput

0.718

High

124851

EIF3F
Eukaryotic translation initiation factor 3 subunit F

5

5

Small-scale

0.714

High

78298

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

4

3

High-throughput

0.699

High

134019

DDX3X
ATP-dependent RNA helicase DDX3X

1

10

Small-scale

0.691

High

907892

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.691

High

929440

RACK1
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.691

High

1032123

DDX60
Probable ATP-dependent RNA helicase DDX60

1

16

High-throughput

0.691

High

1032167

EIF3K
Eukaryotic translation initiation factor 3 subunit K

5

0

High-throughput

0.688

High

319820

HERC2
E3 ubiquitin-protein ligase HERC2

4

10

Small-scale

0.672

High

1032091

TRIPC
E3 ubiquitin-protein ligase TRIP12

3

19

High-throughput

0.667

High

1032101

PRC2B
Protein PRRC2B

3

19

High-throughput

0.667

High

276019

EIF3J
Eukaryotic translation initiation factor 3 subunit J

4

0

Small-scale

0.661

High

1032098

CERKL
Ceramide kinase-like protein

2

2

High-throughput

0.628

High

791533

HD
Huntingtin

2

2

High-throughput

0.621

High

640465

DDX6
Probable ATP-dependent RNA helicase DDX6

1

14

High-throughput

0.618

High

896065

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.618

High

908483

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.618

High

944222

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

High-throughput

0.618

High

1024321

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.618

High

1032093

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.618

High

1032096

EZH2
Histone-lysine N-methyltransferase EZH2

1

17

High-throughput

0.618

High

1032097

DDB1
DNA damage-binding protein 1

1

10

Small-scale

0.618

High

1032106

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.618

High

1032119

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.618

High

1032136

IGSF8
Immunoglobulin superfamily member 8

1

7

High-throughput

0.618

High

1032158

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.618

High

1032159

ANLN
Anillin

1

4

High-throughput

0.618

High

1032174

FZR1
Fizzy-related protein homolog

1

18

High-throughput

0.618

High

1030212

G3BP1
Ras GTPase-activating protein-binding protein 1

2

7

High-throughput

0.611

High

1032085

CUL3
Cullin-3

2

20

High-throughput

0.611

High

1032130

DNJA4
DnaJ homolog subfamily A member 4

2

6

High-throughput

0.611

High

1032154

E41L1
Band 4.1-like protein 1

2

3

High-throughput

0.611

High

1032169

IF172
Intraflagellar transport protein 172 homolog

1

18

High-throughput

0.595

High

1032184

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

12

High-throughput

0.595

High

227358

PRKN
E3 ubiquitin-protein ligase parkin

2

18

High-throughput

0.584

High

386664

P53
Cellular tumor antigen p53

2

4

Small-scale

0.584

High

779353

CCNF
Cyclin-F

2

8

High-throughput

0.584

High

195418

DHX15
ATP-dependent RNA helicase DHX15

1

11

High-throughput

0.575

High

1032084

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.575

High

1032108

PKHA7
Pleckstrin homology domain-containing family A member 7

1

16

High-throughput

0.575

High

369536

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

581714

VCAM1
Vascular cell adhesion protein 1

2

5

High-throughput

0.571

High

592235

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

1032110

ZN746
Zinc finger protein 746

2

2

High-throughput

0.571

High

346700

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.558

High

294796

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.553

High

903197

WDR5
WD repeat-containing protein 5

1

18

High-throughput

0.553

High

1032112

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

1032155

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.553

High

496960

TAU
Microtubule-associated protein tau

2

17

High-throughput

0.552

High

532520

TCTP
Translationally-controlled tumor protein

2

0

Small-scale

0.547

High

117685

MYO1C
Unconventional myosin-Ic

1

7

High-throughput

0.536

High

255141

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.536

High

283511

SRP72
Signal recognition particle subunit SRP72

1

2

High-throughput

0.536

High

380288

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.536

High

416979

IF4E
Eukaryotic translation initiation factor 4E

1

2

High-throughput

0.536

High

529071

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

545847

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

2

High-throughput

0.536

High

643342

HMGB2
High mobility group protein B2

1

20

High-throughput

0.536

High

646865

1433T
14-3-3 protein theta

1

18

High-throughput

0.536

High

649490

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

717785

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.536

High

780696

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

12

High-throughput

0.536

High

805991

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.536

High

827189

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.536

High

840950

MAP2
Methionine aminopeptidase 2

1

3

High-throughput

0.536

High

855633

KIF11
Kinesin-like protein KIF11

1

5

High-throughput

0.536

High

873836

IF5
Eukaryotic translation initiation factor 5

1

4

High-throughput

0.536

High

890135

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.536

High

904521

1433G
14-3-3 protein gamma

1

18

High-throughput

0.536

High

909518

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

911368

RS11
Small ribosomal subunit protein uS17

1

3

High-throughput

0.536

High

927006

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.536

High

1032089

CAPR1
Caprin-1

1

5

High-throughput

0.536

High

1032092

CND2
Condensin complex subunit 2

1

1

High-throughput

0.536

High

1032131

PSPC1
Paraspeckle component 1

1

10

High-throughput

0.536

High

1032143

DNJC2
DnaJ homolog subfamily C member 2

1

6

High-throughput

0.536

High

1032145

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

1032148

RBM42
RNA-binding protein 42

1

10

High-throughput

0.536

High

1032172

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1032175

G3BP2
Ras GTPase-activating protein-binding protein 2

1

7

High-throughput

0.536

High

1032180

DRG1
Developmentally-regulated GTP-binding protein 1

1

6

High-throughput

0.536

High

244387

BRD4
Bromodomain-containing protein 4

2

14

High-throughput

0.533

High

239577

EIF1B
Eukaryotic translation initiation factor 1b

1

2

High-throughput

0.515

High

1032162

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.515

High

336490

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

447938

SRP19
Signal recognition particle 19 kDa protein

1

0

High-throughput

0.513

High

828755

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

475710

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

13

Small-scale

0.501

High

1032095

NEDD8
NEDD8

1

5

Small-scale

0.501

High

1032117

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

3

Small-scale

0.501

High

316875

KLF8
Krueppel-like factor 8

1

14

High-throughput

0.500

High

527437

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

877027

CASP6
Caspase-6

1

0

High-throughput

0.493

High

319184

BRD1
Bromodomain-containing protein 1

1

9

Small-scale

0.489

High

452763

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

821758

NEST
Nestin

1

12

High-throughput

0.489

High

830949

CTCF
Transcriptional repressor CTCF

1

3

High-throughput

0.489

High

989670

CDK18
Cyclin-dependent kinase 18

1

6

High-throughput

0.489

High

1032124

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.489

High

1032103

EXOS6
Exosome complex component MTR3

1

2

High-throughput

0.481

High

117000

SGK1
Serine/threonine-protein kinase Sgk1

1

7

High-throughput

0.479

High

125431

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

High-throughput

0.479

High

203366

IF4G3
Eukaryotic translation initiation factor 4 gamma 3

1

5

High-throughput

0.479

High

224422

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

282641

RNF8
E3 ubiquitin-protein ligase RNF8

1

10

High-throughput

0.479

High

298490

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.479

High

316492

MET18
Histidine protein methyltransferase 1 homolog

1

1

High-throughput

0.479

High

354438

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.479

High

400063

ICAM1
Intercellular adhesion molecule 1

1

6

High-throughput

0.479

High

418238

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

436706

GLI1
Zinc finger protein GLI1

1

3

Small-scale

0.479

High

487401

ANDR
Androgen receptor

1

13

High-throughput

0.479

High

530647

ITA4
Integrin alpha-4

1

2

High-throughput

0.479

High

585657

TFE3
Transcription factor E3

1

7

High-throughput

0.479

High

586723

CSK22
Casein kinase II subunit alpha'

1

12

High-throughput

0.479

High

587555

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

9

High-throughput

0.479

High

596749

CD11B
Cyclin-dependent kinase 11B

1

8

High-throughput

0.479

High

617534

CRCM
Colorectal mutant cancer protein

1

4

High-throughput

0.479

High

618615

IF4B
Eukaryotic translation initiation factor 4B

1

6

Small-scale

0.479

High

625408

CDK2
Cyclin-dependent kinase 2

1

5

High-throughput

0.479

High

632267

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.479

High

673074

CCND2
G1/S-specific cyclin-D2

1

9

Small-scale

0.479

High

684015

1433S
14-3-3 protein sigma

1

18

Small-scale

0.479

High

684687

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

739966

TGFR2
TGF-beta receptor type-2

1

2

Small-scale

0.479

High

749452

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

807711

MAP1B
Microtubule-associated protein 1B

1

7

High-throughput

0.479

High

813432

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.479

High

874893

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

880914

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

912885

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

934138

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.479

High

943784

CCNA1
Cyclin-A1

1

2

High-throughput

0.479

High

998654

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

1022083

NFX1
Transcriptional repressor NF-X1

1

12

High-throughput

0.479

High

1025729

TADBP
TAR DNA-binding protein 43

1

12

High-throughput

0.479

High

1026900

PAK2
Serine/threonine-protein kinase PAK 2

1

2

High-throughput

0.479

High

1032081

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1032082

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

High-throughput

0.479

High

1032090

RBM39
RNA-binding protein 39

1

12

High-throughput

0.479

High

1032094

KIF14
Kinesin-like protein KIF14

1

8

High-throughput

0.479

High

1032099

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

6

High-throughput

0.479

High

1032105

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1032107

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1032109

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

1032116

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

9

High-throughput

0.479

High

1032118

ZN598
E3 ubiquitin-protein ligase ZNF598

1

8

High-throughput

0.479

High

1032120

ZCH18
Zinc finger CCCH domain-containing protein 18

1

19

High-throughput

0.479

High

1032121

SKA3
Spindle and kinetochore-associated protein 3

1

1

Small-scale

0.479

High

1032125

CSK23
Casein kinase II subunit alpha 3

1

16

High-throughput

0.479

High

1032126

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1032127

RIN3
Ras and Rab interactor 3

1

6

High-throughput

0.479

High

1032129

NUDC2
NudC domain-containing protein 2

1

11

High-throughput

0.479

High

1032132

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1032137

KCD12
BTB/POZ domain-containing protein KCTD12

1

4

Small-scale

0.479

High

1032146

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

1032147

ANM1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.479

High

1032151

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1032153

GAN
Gigaxonin

1

1

High-throughput

0.479

High

1032156

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

1032160

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1032168

DUX4
Double homeobox protein 4

1

4

High-throughput

0.479

High

1032170

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1032171

TES
Testin

1

5

High-throughput

0.479

High

1032176

ANGE1
Protein angel homolog 1

1

1

High-throughput

0.479

High

1032177

SRRM2
Serine/arginine repetitive matrix protein 2

1

19

High-throughput

0.479

High

1032181

TRAF6
TNF receptor-associated factor 6

1

9

High-throughput

0.479

High

1032183

RBM8A
RNA-binding protein 8A

1

8

High-throughput

0.479

High

273429

PPM1B
Protein phosphatase 1B

1

0

High-throughput

0.458

High

887833

CD81
CD81 antigen

1

0

High-throughput

0.458

High

1032128

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

1032140

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

976444

ERCC6
DNA excision repair protein ERCC-6

1

14

High-throughput

0.457

High

1032149

KLF16
Krueppel-like factor 16

1

12

High-throughput

0.457

High

374174

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.445

High

1032100

ODFP2
Outer dense fiber protein 2

1

12

High-throughput

0.445

High

1032141

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.445

High

1032150

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

3

High-throughput

0.445

High

1032182

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

18

High-throughput

0.445

High

836828

DNLI4
DNA ligase 4

1

1

High-throughput

0.439

High

1032113

PAXI1
PAX-interacting protein 1

1

14

High-throughput

0.439

High

266352

TAD2A
Transcriptional adapter 2-alpha

1

12

High-throughput

0.437

High

303211

HEXI1
Protein HEXIM1

1

2

High-throughput

0.437

High

351751

SOMA
Somatotropin

1

1

High-throughput

0.437

High

384778

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

569683

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.437

High

651114

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

823967

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.437

High

940855

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

1032083

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

1

High-throughput

0.437

High

1032086

CUL4A
Cullin-4A

1

20

Small-scale

0.437

High

1032115

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

1032122

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.437

High

1032133

ESR2
Estrogen receptor beta

1

13

High-throughput

0.437

High

1032134

TNR14
Tumor necrosis factor receptor superfamily member 14

1

1

High-throughput

0.437

High

1032138

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.437

High

1032139

CIC
Protein capicua homolog

1

20

High-throughput

0.437

High

1032142

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.437

High

1032157

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

3

High-throughput

0.437

High

1032161

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.437

High

1032163

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1032164

CDK12
Cyclin-dependent kinase 12

1

7

High-throughput

0.437

High

1032165

HECW2
E3 ubiquitin-protein ligase HECW2

1

9

High-throughput

0.437

High

1032173

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.437

High

1032178

CD11A
Cyclin-dependent kinase 11A

1

8

High-throughput

0.437

High

47678

A0AUL9
ATG2A protein

1

2

High-throughput

0.407

High

1032135

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

3

High-throughput

0.407

High

1032152

ZDHC5
Palmitoyltransferase ZDHHC5

1

4

High-throughput

0.407

High

1032104

LITD1
LINE-1 type transposase domain-containing protein 1

2

0

High-throughput

0.313

High

1032111

CLC4G
C-type lectin domain family 4 member G

1

0

High-throughput

0.299

High

1032166

STX18
Syntaxin-18

1

0

High-throughput

0.279

Low

87272

CE058
Putative uncharacterized protein C5orf58

1

0

High-throughput

0.269

Low

353289

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

536354

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024