Protein: HPBP1
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)

Gene: HPBP1, HSPBP1
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q9NZL4

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0004857 - enzyme inhibitor activity
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

504872

HSP7C
Heat shock cognate 71 kDa protein

12

10

Small-scale

0.761

High

871809

HSP72
Heat shock-related 70 kDa protein 2

7

6

High-throughput

0.690

High

961299

HSF1
Heat shock factor protein 1

5

6

High-throughput

0.659

High

564199

HSP76
Heat shock 70 kDa protein 6

3

5

High-throughput

0.656

High

1349258

CHIP
E3 ubiquitin-protein ligase CHIP

3

2

Small-scale

0.656

High

1107852

EDRF1
Erythroid differentiation-related factor 1

4

1

High-throughput

0.638

High

714444

HSP74
Heat shock 70 kDa protein 4

2

7

Small-scale

0.629

High

1077609

ELF2
ETS-related transcription factor Elf-2

3

1

High-throughput

0.609

High

1263332

MT21A
Protein N-lysine methyltransferase METTL21A

3

1

High-throughput

0.609

High

502622

BIP
Endoplasmic reticulum chaperone BiP

2

10

Small-scale

0.595

High

160210

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.574

High

161724

GAK
Cyclin-G-associated kinase

2

1

High-throughput

0.574

High

257108

DJC13
DnaJ homolog subfamily C member 13

2

2

High-throughput

0.574

High

977931

HSF2
Heat shock factor protein 2

2

6

High-throughput

0.574

High

1075761

SF01
Splicing factor 1

2

4

High-throughput

0.574

High

1246048

NEDD1
Protein NEDD1

2

3

High-throughput

0.574

High

1189474

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.573

High

692193

ELF1
ETS-related transcription factor Elf-1

2

1

High-throughput

0.567

High

60432

POTEF
POTE ankyrin domain family member F

1

4

High-throughput

0.536

High

735024

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

3

High-throughput

0.536

High

1053232

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.536

High

1077969

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.536

High

1305056

TTC1
Tetratricopeptide repeat protein 1

1

3

High-throughput

0.536

High

1346976

KBTB4
Kelch repeat and BTB domain-containing protein 4

2

7

Small-scale

0.533

High

270855

PGRP1
Peptidoglycan recognition protein 1

1

0

Small-scale

0.527

High

614153

TBG1
Tubulin gamma-1 chain

2

3

High-throughput

0.521

High

805479

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

2

High-throughput

0.521

High

925675

RAC1
Ras-related C3 botulinum toxin substrate 1

2

7

High-throughput

0.521

High

201450

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

575861

VINC
Vinculin

1

0

High-throughput

0.513

High

1316099

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.513

High

395933

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

751866

GRP75
Stress-70 protein, mitochondrial

1

13

Small-scale

0.501

High

678582

MK04
Mitogen-activated protein kinase 4

1

3

High-throughput

0.489

High

794433

GRK6
G protein-coupled receptor kinase 6

1

2

High-throughput

0.489

High

864026

CLH2
Clathrin heavy chain 2

1

2

High-throughput

0.489

High

883438

CF298
Cilia- and flagella-associated protein 298

1

1

High-throughput

0.489

High

952886

FOXK1
Forkhead box protein K1

1

5

High-throughput

0.489

High

1021172

FOXC1
Forkhead box protein C1

1

8

High-throughput

0.489

High

1039902

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

1101070

QSER1
Glutamine and serine-rich protein 1

1

2

High-throughput

0.489

High

1134157

UBAP2
Ubiquitin-associated protein 2

1

2

High-throughput

0.489

High

1190115

MAVS
Mitochondrial antiviral-signaling protein

1

2

High-throughput

0.489

High

1199106

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.489

High

1260099

IASPP
RelA-associated inhibitor

1

2

High-throughput

0.489

High

1270623

STAM1
Signal transducing adapter molecule 1

1

1

High-throughput

0.489

High

1286392

ULK4
Serine/threonine-protein kinase ULK4

1

2

High-throughput

0.489

High

1288169

ESS2
Splicing factor ESS-2 homolog

1

2

High-throughput

0.489

High

1290920

ZN503
Zinc finger protein 503

1

1

High-throughput

0.489

High

1330353

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

3

High-throughput

0.489

High

1332342

ILRUN
Protein ILRUN

1

1

High-throughput

0.489

High

1333198

ZN703
Zinc finger protein 703

1

1

High-throughput

0.489

High

1344950

LATS2
Serine/threonine-protein kinase LATS2

1

1

High-throughput

0.489

High

1345641

NRBP2
Nuclear receptor-binding protein 2

1

2

High-throughput

0.489

High

1349256

MKLN1
Muskelin

1

3

High-throughput

0.489

High

1349262

TACC3
Transforming acidic coiled-coil-containing protein 3

1

1

High-throughput

0.489

High

553918

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

681632

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.479

High

714085

HS71L
Heat shock 70 kDa protein 1-like

1

9

High-throughput

0.479

High

1036154

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1042700

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1273174

TNR14
Tumor necrosis factor receptor superfamily member 14

1

3

High-throughput

0.479

High

1305127

DNJC7
DnaJ homolog subfamily C member 7

1

4

High-throughput

0.479

High

1319018

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

5

High-throughput

0.479

High

1326186

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

2

High-throughput

0.479

High

780225

CCNF
Cyclin-F

1

4

High-throughput

0.470

High

1294642

Q96IS6
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.470

High

802754

CRK
Adapter molecule crk

1

0

High-throughput

0.458

High

1062090

UBX2B
UBX domain-containing protein 2B

1

0

High-throughput

0.458

High

1294083

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1316781

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1318313

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.458

High

1349255

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

833828

CLK1
Dual specificity protein kinase CLK1

1

8

High-throughput

0.457

High

890868

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.457

High

72238

B3KTT5
cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1

1

7

High-throughput

0.457

High

483807

HS71B
Heat shock 70 kDa protein 1B

1

6

High-throughput

0.445

High

875372

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

1130671

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

328062

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

1

High-throughput

0.439

High

206081

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

385627

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

652456

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

721638

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

909243

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1028439

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

1

High-throughput

0.437

High

1101345

CL16A
Protein CLEC16A

1

3

High-throughput

0.437

High

1166014

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1172036

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1216848

ARMC8
Armadillo repeat-containing protein 8

1

8

High-throughput

0.437

High

1243141

FXL13
F-box and leucine-rich repeat protein 13

1

1

Small-scale

0.437

High

1331482

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1332700

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1333686

BRD9
Bromodomain-containing protein 9

1

11

High-throughput

0.437

High

1336041

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.437

High

1349253

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.437

High

1349257

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.437

High

1349263

DUS10
Dual specificity protein phosphatase 10

1

2

High-throughput

0.437

High

378191

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1137584

RIF1
Telomere-associated protein RIF1

1

3

High-throughput

0.417

High

92706

E9PQQ4
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.407

High

529815

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.407

High

1037417

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.407

High

1153416

PKHA7
Pleckstrin homology domain-containing family A member 7

1

7

High-throughput

0.407

High

1285458

Q96BE0
Heat shock cognate 71 kDa protein

1

10

High-throughput

0.407

High

1349260

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

3

High-throughput

0.407

High

836475

5NTC
Cytosolic purine 5'-nucleotidase

3

0

High-throughput

0.347

High

862253

ARFP1
Arfaptin-1

2

0

High-throughput

0.328

High

1102961

QRIC1
Transcriptional regulator QRICH1

2

0

High-throughput

0.328

High

1286998

FWCH2
FLYWCH family member 2

2

0

High-throughput

0.328

High

1291653

HMCES
Abasic site processing protein HMCES

2

0

High-throughput

0.328

High

1309391

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

2

0

High-throughput

0.328

High

1346853

ARMC1
Armadillo repeat-containing protein 1

2

0

High-throughput

0.328

High

1047467

PEBB
Core-binding factor subunit beta

2

0

High-throughput

0.318

High

1302775

RUFY1
RUN and FYVE domain-containing protein 1

2

0

High-throughput

0.318

High

1133133

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

2

0

High-throughput

0.304

High

267197

GEMI
Geminin

1

0

High-throughput

0.279

Low

320579

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.279

Low

443851

VIME
Vimentin

1

0

High-throughput

0.279

Low

546421

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.279

Low

603886

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

0

High-throughput

0.279

Low

789095

ABL2
Tyrosine-protein kinase ABL2

1

0

High-throughput

0.279

Low

841020

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.279

Low

843513

ANX11
Annexin A11

1

0

High-throughput

0.279

Low

1018876

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.279

Low

1056766

PUM1
Pumilio homolog 1

1

0

High-throughput

0.279

Low

1073737

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.279

Low

1218589

CC117
Coiled-coil domain-containing protein 117

1

0

High-throughput

0.279

Low

1251931

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.279

Low

1332485

ESRP2
Epithelial splicing regulatory protein 2

1

0

High-throughput

0.279

Low

1342927

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.279

Low

1349254

DBNL
Drebrin-like protein

1

0

High-throughput

0.279

Low

1349261

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.279

Low

1189668

K1C27
Keratin, type I cytoskeletal 27

1

0

High-throughput

0.251

Low

101236

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

303511

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

673633

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.249

Low

965869

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.249

Low

1054632

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

1199619

LBN
Limbin

1

0

High-throughput

0.249

Low

1239174

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.249

Low

1245209

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

1281865

FBX32
F-box only protein 32

1

0

High-throughput

0.249

Low

1286548

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1298676

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1347290

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1349259

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.249

Low

47693

A0AUL9
ATG2A protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024