Protein: C5AR1
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)

Gene: C5AR1
Organism: Homo sapiens
Interactions: 151
UniProt ID: P21730

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0002430 - complement receptor mediated signaling pathway
GO:0004878 - complement component C5a receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600761

MTR1L
Melatonin-related receptor

1

17

High-throughput

0.691

High

600742

ARRB2
Beta-arrestin-2

1

13

Small-scale

0.618

High

600750

ARRB1
Beta-arrestin-1

1

13

Small-scale

0.618

High

391329

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

15

Small-scale

0.575

High

444666

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

16

Small-scale

0.575

High

600745

WASP
Actin nucleation-promoting factor WAS

1

3

Small-scale

0.573

High

62557

TCAF2
TRPM8 channel-associated factor 2

1

2

High-throughput

0.536

High

167840

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.536

High

173433

RER1
Protein RER1

1

3

High-throughput

0.536

High

240864

S19A2
Thiamine transporter 1

1

9

High-throughput

0.536

High

277646

PRAF3
PRA1 family protein 3

1

5

High-throughput

0.536

High

530829

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

600741

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

20

High-throughput

0.536

High

600743

ATP7B
Copper-transporting ATPase 2

1

20

High-throughput

0.536

High

600747

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

High-throughput

0.536

High

600749

AGRE5
Adhesion G protein-coupled receptor E5

1

5

High-throughput

0.536

High

600751

CAV2
Caveolin-2

1

4

High-throughput

0.536

High

600752

CTR2
Cationic amino acid transporter 2

1

11

High-throughput

0.536

High

600754

AT12A
Potassium-transporting ATPase alpha chain 2

1

20

High-throughput

0.536

High

600755

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

20

High-throughput

0.536

High

600758

CLN3
Battenin

1

1

High-throughput

0.536

High

600759

ATM
Serine-protein kinase ATM

1

17

High-throughput

0.536

High

600760

PKD2
Polycystin-2

1

1

High-throughput

0.536

High

600762

ITPR2
Inositol 1,4,5-trisphosphate receptor type 2

1

2

High-throughput

0.536

High

600763

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

20

High-throughput

0.536

High

600764

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

11

High-throughput

0.536

High

600771

CSCL2
CSC1-like protein 2

1

5

High-throughput

0.536

High

600773

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

9

High-throughput

0.536

High

600775

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

9

High-throughput

0.536

High

600778

S39A4
Zinc transporter ZIP4

1

9

High-throughput

0.536

High

600781

AN13D
Ankyrin repeat domain-containing protein 13D

1

5

High-throughput

0.536

High

600797

T161B
Transmembrane protein 161B

1

8

High-throughput

0.536

High

600799

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

6

High-throughput

0.536

High

600803

CIP2A
Protein CIP2A

1

5

High-throughput

0.536

High

600804

SPPL3
Signal peptide peptidase-like 3

1

5

High-throughput

0.536

High

600809

LMBR1
Limb region 1 protein homolog

1

3

High-throughput

0.536

High

600811

CTR3
Cationic amino acid transporter 3

1

10

High-throughput

0.536

High

600813

YLAT2
Y+L amino acid transporter 2

1

12

High-throughput

0.536

High

600815

CDS1
Phosphatidate cytidylyltransferase 1

1

2

High-throughput

0.536

High

600826

RADIL
Ras-associating and dilute domain-containing protein

1

16

High-throughput

0.536

High

600828

XPO6
Exportin-6

1

3

High-throughput

0.536

High

600831

TTYH2
Protein tweety homolog 2

1

3

High-throughput

0.536

High

600836

YIPF3
Protein YIPF3

1

8

High-throughput

0.536

High

600842

GOLP3
Golgi phosphoprotein 3

1

5

High-throughput

0.536

High

600843

XKR8
XK-related protein 8

1

1

High-throughput

0.536

High

600848

GPC5C
G-protein coupled receptor family C group 5 member C

1

5

High-throughput

0.536

High

600849

SERC1
Serine incorporator 1

1

3

High-throughput

0.536

High

600854

S39A1
Zinc transporter ZIP1

1

9

High-throughput

0.536

High

600857

S39AA
Zinc transporter ZIP10

1

9

High-throughput

0.536

High

600861

AGRG1
Adhesion G-protein coupled receptor G1

1

5

High-throughput

0.536

High

376421

APOB
Apolipoprotein B-100

1

0

High-throughput

0.513

High

577724

NELFE
Negative elongation factor E

1

0

High-throughput

0.513

High

600757

NTCP7
Sodium/bile acid cotransporter 7

1

0

High-throughput

0.513

High

600801

S35G2
Solute carrier family 35 member G2

1

0

High-throughput

0.513

High

600810

CANT1
Soluble calcium-activated nucleotidase 1

1

0

High-throughput

0.513

High

344755

CO5
Complement C5

1

8

Small-scale

0.501

High

47706

S12A8
Solute carrier family 12 member 8

1

15

High-throughput

0.489

High

156459

SCAM3
Secretory carrier-associated membrane protein 3

1

6

High-throughput

0.489

High

163564

BTAF1
TATA-binding protein-associated factor 172

1

9

High-throughput

0.489

High

168503

SCAM2
Secretory carrier-associated membrane protein 2

1

6

High-throughput

0.489

High

175558

TM9S1
Transmembrane 9 superfamily member 1

1

7

High-throughput

0.489

High

213194

SNG2
Synaptogyrin-2

1

5

High-throughput

0.489

High

237785

TSN3
Tetraspanin-3

1

16

High-throughput

0.489

High

256726

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

9

High-throughput

0.489

High

276516

SC5D
Lathosterol oxidase

1

9

High-throughput

0.489

High

297152

IPO13
Importin-13

1

14

High-throughput

0.489

High

327132

CF047
Uncharacterized protein C6orf47

1

1

High-throughput

0.489

High

335652

COX1
Cytochrome c oxidase subunit 1

1

2

High-throughput

0.489

High

503202

PPAL
Lysosomal acid phosphatase

1

1

High-throughput

0.489

High

573570

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

13

High-throughput

0.489

High

600744

FDFT
Squalene synthase

1

1

High-throughput

0.489

High

600748

PTSS1
Phosphatidylserine synthase 1

1

6

High-throughput

0.489

High

600756

KDSR
3-ketodihydrosphingosine reductase

1

5

High-throughput

0.489

High

600766

MBRL
Membralin

1

3

High-throughput

0.489

High

600767

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

4

High-throughput

0.489

High

600768

RABL3
Rab-like protein 3

1

6

High-throughput

0.489

High

600769

TT39A
Tetratricopeptide repeat protein 39A

1

1

High-throughput

0.489

High

600770

S35F1
Solute carrier family 35 member F1

1

7

High-throughput

0.489

High

600772

TM164
Transmembrane protein 164

1

2

High-throughput

0.489

High

600774

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.489

High

600776

RINT1
RAD50-interacting protein 1

1

4

High-throughput

0.489

High

600777

ZNT6
Zinc transporter 6

1

6

High-throughput

0.489

High

600779

PAQR3
Progestin and adipoQ receptor family member 3

1

1

High-throughput

0.489

High

600780

THADA
tRNA

1

4

High-throughput

0.489

High

600782

DPH6
Diphthine--ammonia ligase

1

2

High-throughput

0.489

High

600783

DYM
Dymeclin

1

5

High-throughput

0.489

High

600786

RETR3
Reticulophagy regulator 3

1

2

High-throughput

0.489

High

600787

DAAF5
Dynein axonemal assembly factor 5

1

6

High-throughput

0.489

High

600788

S35F2
Solute carrier family 35 member F2

1

7

High-throughput

0.489

High

600789

K2013
Uncharacterized protein KIAA2013

1

3

High-throughput

0.489

High

600790

CKLF4
CKLF-like MARVEL transmembrane domain-containing protein 4

1

6

High-throughput

0.489

High

600791

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

5

High-throughput

0.489

High

600792

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

1

High-throughput

0.489

High

600793

STAG2
Cohesin subunit SA-2

1

2

High-throughput

0.489

High

600794

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

4

High-throughput

0.489

High

600795

ARL10
ADP-ribosylation factor-like protein 10

1

7

High-throughput

0.489

High

600796

S38A9
Neutral amino acid transporter 9

1

1

High-throughput

0.489

High

600798

MFSD8
Major facilitator superfamily domain-containing protein 8

1

10

High-throughput

0.489

High

600800

GOGA5
Golgin subfamily A member 5

1

4

High-throughput

0.489

High

600802

TBC15
TBC1 domain family member 15

1

5

High-throughput

0.489

High

600805

PIGO
GPI ethanolamine phosphate transferase 3

1

8

High-throughput

0.489

High

600806

CHPT1
Cholinephosphotransferase 1

1

5

High-throughput

0.489

High

600807

S35F5
Solute carrier family 35 member F5

1

7

High-throughput

0.489

High

600808

STAG1
Cohesin subunit SA-1

1

2

High-throughput

0.489

High

600812

BRI3B
BRI3-binding protein

1

1

High-throughput

0.489

High

600814

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.489

High

600816

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

20

High-throughput

0.489

High

600817

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

1

High-throughput

0.489

High

600818

S2546
Mitochondrial outer membrane protein SLC25A46

1

4

High-throughput

0.489

High

600819

EVI5L
EVI5-like protein

1

3

High-throughput

0.489

High

600820

F241B
Protein FAM241B

1

4

High-throughput

0.489

High

600821

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.489

High

600823

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

3

High-throughput

0.489

High

600824

CERS2
Ceramide synthase 2

1

17

High-throughput

0.489

High

600825

RN185
E3 ubiquitin-protein ligase RNF185

1

8

High-throughput

0.489

High

600827

MBOA7
Lysophospholipid acyltransferase 7

1

9

High-throughput

0.489

High

600829

SGMR1
Sigma non-opioid intracellular receptor 1

1

6

High-throughput

0.489

High

600830

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

3

High-throughput

0.489

High

600832

GCP2
Gamma-tubulin complex component 2

1

14

High-throughput

0.489

High

600833

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.489

High

600834

FUT8
Alpha-(1,6)-fucosyltransferase

1

1

High-throughput

0.489

High

600835

XPO4
Exportin-4

1

15

High-throughput

0.489

High

600837

UN93B
Protein unc-93 homolog B1

1

4

High-throughput

0.489

High

600838

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

1

High-throughput

0.489

High

600839

TM245
Transmembrane protein 245

1

1

High-throughput

0.489

High

600841

GLP3L
Golgi phosphoprotein 3-like

1

5

High-throughput

0.489

High

600844

REEP4
Receptor expression-enhancing protein 4

1

5

High-throughput

0.489

High

600845

AT133
Polyamine-transporting ATPase 13A3

1

20

High-throughput

0.489

High

600846

CERS4
Ceramide synthase 4

1

17

High-throughput

0.489

High

600847

RRAGC
Ras-related GTP-binding protein C

1

4

High-throughput

0.489

High

600850

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

4

High-throughput

0.489

High

600851

RMND1
Required for meiotic nuclear division protein 1 homolog

1

3

High-throughput

0.489

High

600852

T161A
Transmembrane protein 161A

1

8

High-throughput

0.489

High

600853

ELOV2
Very long chain fatty acid elongase 2

1

5

High-throughput

0.489

High

600855

B4GT7
Beta-1,4-galactosyltransferase 7

1

1

High-throughput

0.489

High

600858

TPC1
Two pore channel protein 1

1

3

High-throughput

0.489

High

600859

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

1

High-throughput

0.489

High

600860

TNPO3
Transportin-3

1

12

High-throughput

0.489

High

600753

SC5A3
Sodium/myo-inositol cotransporter

1

4

High-throughput

0.445

High

474440

GPHRB
Golgi pH regulator B

1

15

High-throughput

0.437

High

81785

GPHRA
Golgi pH regulator A

1

15

High-throughput

0.407

High

169385

BET1
BET1 homolog

1

0

High-throughput

0.279

Low

281541

WFS1
Wolframin

1

0

High-throughput

0.279

Low

300559

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.279

Low

600746

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.279

Low

600765

GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

1

0

High-throughput

0.279

Low

600784

SETX
Probable helicase senataxin

1

0

High-throughput

0.279

Low

600785

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

600822

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

600840

PIGM
GPI mannosyltransferase 1

1

0

High-throughput

0.279

Low

600856

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024