Protein: CASC3
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)

Gene: CASC3
Organism: Homo sapiens
Interactions: 136
UniProt ID: O15234

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

172829

IF4A3
Eukaryotic initiation factor 4A-III

16

6

Small-scale

0.986

High

172839

MGN
Protein mago nashi homolog

10

0

Small-scale

0.922

High

172933

RBM8A
RNA-binding protein 8A

7

8

Small-scale

0.741

High

172903

REN3B
Regulator of nonsense transcripts 3B

5

2

Small-scale

0.713

High

172914

DDX21
Nucleolar RNA helicase 2

1

4

High-throughput

0.691

High

172857

TRA2A
Transformer-2 protein homolog alpha

3

5

High-throughput

0.667

High

172884

SNIP1
Smad nuclear-interacting protein 1

3

2

High-throughput

0.667

High

172912

LUC7L
Putative RNA-binding protein Luc7-like 1

3

1

High-throughput

0.667

High

172930

LC7L2
Putative RNA-binding protein Luc7-like 2

3

1

High-throughput

0.667

High

172890

RENT1
Regulator of nonsense transcripts 1

3

1

Small-scale

0.664

High

172907

REN3A
Regulator of nonsense transcripts 3A

3

1

Small-scale

0.662

High

172823

U2AF2
Splicing factor U2AF 65 kDa subunit

2

10

High-throughput

0.628

High

172833

CDX1
Homeobox protein CDX-1

2

6

High-throughput

0.628

High

172837

CLK2
Dual specificity protein kinase CLK2

2

6

High-throughput

0.628

High

172855

ELAV2
ELAV-like protein 2

2

7

High-throughput

0.628

High

172879

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

2

2

High-throughput

0.628

High

172881

CELF5
CUGBP Elav-like family member 5

2

5

High-throughput

0.628

High

172908

PININ
Pinin

2

1

High-throughput

0.628

High

172822

DDX6
Probable ATP-dependent RNA helicase DDX6

1

7

High-throughput

0.618

High

172889

ESR2
Estrogen receptor beta

2

20

High-throughput

0.614

High

172867

LSM12
Protein LSM12

2

2

High-throughput

0.611

High

172900

PYM1
Partner of Y14 and mago

2

0

High-throughput

0.602

High

172913

PRDM5
PR domain zinc finger protein 5

2

0

High-throughput

0.602

High

172919

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.602

High

172920

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

0

High-throughput

0.585

High

172869

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

2

High-throughput

0.584

High

172866

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

172926

DICER
Endoribonuclease Dicer

1

6

Small-scale

0.575

High

172810

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

172827

BMI1
Polycomb complex protein BMI-1

2

5

High-throughput

0.571

High

172846

CDK6
Cyclin-dependent kinase 6

1

1

Small-scale

0.569

High

172806

NBN
Nibrin

1

1

High-throughput

0.541

High

172819

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.541

High

172821

APC
Adenomatous polyposis coli protein

1

12

High-throughput

0.541

High

172828

PHB1
Prohibitin 1

1

2

High-throughput

0.541

High

172831

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

6

High-throughput

0.541

High

172860

CASP8
Caspase-8

1

1

High-throughput

0.541

High

172887

TSC1
Hamartin

1

8

High-throughput

0.541

High

172803

PER1
Period circadian protein homolog 1

1

1

High-throughput

0.536

High

172804

KIF1C
Kinesin-like protein KIF1C

1

5

High-throughput

0.536

High

172805

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

4

High-throughput

0.536

High

172815

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.536

High

172818

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

2

High-throughput

0.536

High

172830

MNDA
Myeloid cell nuclear differentiation antigen

1

5

High-throughput

0.536

High

172832

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

172838

CLK3
Dual specificity protein kinase CLK3

1

6

High-throughput

0.536

High

172844

SRSF3
Serine/arginine-rich splicing factor 3

1

9

High-throughput

0.536

High

172850

SRSF1
Serine/arginine-rich splicing factor 1

1

9

High-throughput

0.536

High

172853

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.536

High

172856

SRSF6
Serine/arginine-rich splicing factor 6

1

8

High-throughput

0.536

High

172858

MAP7
Ensconsin

1

16

High-throughput

0.536

High

172861

RNPS1
RNA-binding protein with serine-rich domain 1

1

5

High-throughput

0.536

High

172862

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

10

High-throughput

0.536

High

172863

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

172864

SRSF7
Serine/arginine-rich splicing factor 7

1

10

High-throughput

0.536

High

172865

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

10

High-throughput

0.536

High

172870

L2GL2
LLGL scribble cell polarity complex component 2

1

3

High-throughput

0.536

High

172875

NUFP2
FMR1-interacting protein NUFIP2

1

1

High-throughput

0.536

High

172877

THOC4
THO complex subunit 4

1

4

High-throughput

0.536

High

172878

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.536

High

172882

KDM1B
Lysine-specific histone demethylase 2

1

6

High-throughput

0.536

High

172886

PSPC1
Paraspeckle component 1

1

9

High-throughput

0.536

High

172888

LAR4B
La-related protein 4B

1

2

High-throughput

0.536

High

172892

MED12
Mediator of RNA polymerase II transcription subunit 12

1

18

High-throughput

0.536

High

172895

PABP5
Polyadenylate-binding protein 5

1

7

High-throughput

0.536

High

172901

MCRI2
MAPK regulated corepressor interacting protein 2

1

2

High-throughput

0.536

High

172911

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.536

High

172922

PUF60
Poly(U)-binding-splicing factor PUF60

1

10

High-throughput

0.536

High

172924

RALY
RNA-binding protein Raly

1

3

High-throughput

0.536

High

172928

YBOX2
Y-box-binding protein 2

1

5

High-throughput

0.536

High

172931

CCDC9
Coiled-coil domain-containing protein 9

1

1

High-throughput

0.536

High

172825

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.518

High

127669

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

172802

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

172814

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

172836

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

172841

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

172905

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

172906

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

0

High-throughput

0.513

High

172915

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

172917

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

172918

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.513

High

172923

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.513

High

172820

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.494

High

172854

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

2

High-throughput

0.494

High

172807

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

1

2

High-throughput

0.489

High

172899

RTP3
Receptor-transporting protein 3

1

1

High-throughput

0.489

High

172925

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

1

High-throughput

0.489

High

172842

GRB2
Growth factor receptor-bound protein 2

1

13

High-throughput

0.481

High

47723

RBM47
RNA-binding protein 47

1

6

High-throughput

0.479

High

162207

XPO1
Exportin-1

1

6

High-throughput

0.479

High

172809

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.479

High

172811

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

172812

MYCN
N-myc proto-oncogene protein

1

17

High-throughput

0.479

High

172813

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

172816

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

172817

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.479

High

172824

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

9

High-throughput

0.479

High

172826

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

172834

PRC2A
Protein PRRC2A

1

12

High-throughput

0.479

High

172835

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

172840

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

172845

RBM3
RNA-binding protein 3

1

5

Small-scale

0.479

High

172847

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

172848

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

172849

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.479

High

172851

EP300
Histone acetyltransferase p300

1

15

High-throughput

0.479

High

172852

GRSF1
G-rich sequence factor 1

1

6

High-throughput

0.479

High

172859

RBM39
RNA-binding protein 39

1

9

High-throughput

0.479

High

172871

MEX3B
RNA-binding protein MEX3B

1

2

High-throughput

0.479

High

172891

DAZL
Deleted in azoospermia-like

1

9

High-throughput

0.479

High

172893

FUBP1
Far upstream element-binding protein 1

1

4

High-throughput

0.479

High

172897

ATX2
Ataxin-2

1

8

High-throughput

0.479

High

172898

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

1

High-throughput

0.479

High

172902

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.479

High

172904

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

172921

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

172927

R3HD2
R3H domain-containing protein 2

1

8

High-throughput

0.479

High

172929

TR150
Thyroid hormone receptor-associated protein 3

1

9

Small-scale

0.479

High

172932

YTHD2
YTH domain-containing family protein 2

1

5

High-throughput

0.479

High

172883

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

172896

PRR11
Proline-rich protein 11

1

0

High-throughput

0.458

High

172910

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

70100

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

2

High-throughput

0.445

High

172808

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

Small-scale

0.445

High

172843

YBOX1
Y-box-binding protein 1

1

5

High-throughput

0.445

High

172868

CP135
Centrosomal protein of 135 kDa

1

2

High-throughput

0.445

High

172894

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

2

High-throughput

0.445

High

172872

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

172876

PAQR2
Adiponectin receptor protein 2

1

1

Small-scale

0.437

High

172909

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

172916

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

172873

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

172874

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.279

Low

172885

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

172880

OTU6B
Deubiquitinase OTUD6B

1

0

Small-scale

0.269

Low


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Last updated: 15 Jul 2024