Protein: PFD1
Prefoldin subunit 1

Gene: PFD1, PFDN1
Organism: Homo sapiens
Interactions: 156
UniProt ID: O60925

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0016272 - prefoldin complex
GO:0044183 - protein folding chaperone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

246057

PFD2
Prefoldin subunit 2

5

1

Small-scale

0.920

High

246025

PFD5
Prefoldin subunit 5

5

1

Small-scale

0.915

High

171560

PFD6
Prefoldin subunit 6

3

1

High-throughput

0.861

High

245957

PFD3
Prefoldin subunit 3

3

1

High-throughput

0.861

High

246047

PFD4
Prefoldin subunit 4

3

1

High-throughput

0.861

High

245945

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.691

High

245949

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.691

High

245950

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.691

High

245965

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.691

High

246030

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.691

High

246001

TBA1A
Tubulin alpha-1A chain

4

2

Small-scale

0.683

High

246056

AAKG3
5'-AMP-activated protein kinase subunit gamma-3

4

0

High-throughput

0.670

High

245961

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

3

5

High-throughput

0.667

High

245969

MK07
Mitogen-activated protein kinase 7

4

0

High-throughput

0.661

High

246048

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.656

High

246022

DCAF5
DDB1- and CUL4-associated factor 5

2

4

High-throughput

0.628

High

246038

SKI8
Superkiller complex protein 8

2

5

High-throughput

0.628

High

245972

HDAC1
Histone deacetylase 1

3

0

High-throughput

0.622

High

246064

GIT1
ARF GTPase-activating protein GIT1

3

1

High-throughput

0.615

High

246034

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

2

4

High-throughput

0.611

High

246046

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

245926

KTNA1
Katanin p60 ATPase-containing subunit A1

1

1

High-throughput

0.536

High

245958

DCAF7
DDB1- and CUL4-associated factor 7

1

4

High-throughput

0.536

High

245960

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

5

High-throughput

0.536

High

245963

TBA1B
Tubulin alpha-1B chain

1

2

High-throughput

0.536

High

245973

ARHG7
Rho guanine nucleotide exchange factor 7

1

1

High-throughput

0.536

High

245979

ARHG6
Rho guanine nucleotide exchange factor 6

1

1

High-throughput

0.536

High

245987

DCAF6
DDB1- and CUL4-associated factor 6

1

5

High-throughput

0.536

High

246035

KATL1
Katanin p60 ATPase-containing subunit A-like 1

1

1

High-throughput

0.536

High

124351

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.518

High

245934

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.518

High

245967

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.518

High

246053

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.518

High

246054

WRP73
WD repeat-containing protein WRAP73

1

5

High-throughput

0.515

High

245924

ROCK2
Rho-associated protein kinase 2

1

0

High-throughput

0.513

High

245925

TACC1
Transforming acidic coiled-coil-containing protein 1

1

0

High-throughput

0.513

High

245933

TYSY
Thymidylate synthase

1

0

High-throughput

0.513

High

245943

MOES
Moesin

1

0

High-throughput

0.513

High

245964

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

246026

PKP4
Plakophilin-4

1

0

High-throughput

0.513

High

246041

PDCL3
Phosducin-like protein 3

1

0

High-throughput

0.513

High

246051

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

0

High-throughput

0.513

High

245993

JADE1
Protein Jade-1

1

1

High-throughput

0.508

High

245951

HAP1
Huntingtin-associated protein 1

1

1

High-throughput

0.494

High

245952

AF10
Protein AF-10

1

1

High-throughput

0.489

High

245974

GIT2
ARF GTPase-activating protein GIT2

1

1

High-throughput

0.489

High

245996

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

4

High-throughput

0.489

High

246003

WDR86
WD repeat-containing protein 86

1

6

High-throughput

0.489

High

246009

NEDD1
Protein NEDD1

1

5

High-throughput

0.489

High

246021

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.489

High

246052

DTL
Denticleless protein homolog

1

3

High-throughput

0.489

High

210868

GET3
ATPase GET3

1

0

High-throughput

0.486

High

245927

SC31A
Protein transport protein Sec31A

1

0

High-throughput

0.486

High

245931

ALBU
Albumin

1

0

High-throughput

0.486

High

245953

SUMO3
Small ubiquitin-related modifier 3

1

0

High-throughput

0.486

High

245959

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.486

High

245976

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.486

High

245992

MYOME
Myomegalin

1

0

High-throughput

0.486

High

246033

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.486

High

246037

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.486

High

246040

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

0

High-throughput

0.486

High

148021

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.479

High

245930

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

245932

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

245942

TBG1
Tubulin gamma-1 chain

1

2

High-throughput

0.479

High

245954

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.479

High

245971

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

3

High-throughput

0.479

High

245975

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

245994

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

1

High-throughput

0.479

High

246008

POC1A
POC1 centriolar protein homolog A

1

5

High-throughput

0.479

High

246010

POC1B
POC1 centriolar protein homolog B

1

5

High-throughput

0.479

High

246011

GEMI5
Gem-associated protein 5

1

5

High-throughput

0.479

High

246060

PRP19
Pre-mRNA-processing factor 19

1

5

High-throughput

0.479

High

246061

FBW1A
F-box/WD repeat-containing protein 1A

1

4

High-throughput

0.479

High

246067

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.479

High

196922

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

6

High-throughput

0.470

High

154900

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.464

High

245936

COT1
COUP transcription factor 1

1

1

High-throughput

0.464

High

47726

RBM47
RNA-binding protein 47

1

0

High-throughput

0.458

High

245980

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.458

High

245983

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

245995

SKI3
Superkiller complex protein 3

1

0

High-throughput

0.458

High

245999

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

246012

SMAP2
Stromal membrane-associated protein 2

1

0

High-throughput

0.458

High

246015

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

246018

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.458

High

246029

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

High-throughput

0.458

High

246031

DUS9
Dual specificity protein phosphatase 9

1

0

High-throughput

0.458

High

246036

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

0

High-throughput

0.458

High

246042

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

246050

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

246055

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

245991

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

238288

REV3L
DNA polymerase zeta catalytic subunit

1

1

High-throughput

0.437

High

245935

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

1

High-throughput

0.437

High

245955

FBXW4
F-box/WD repeat-containing protein 4

1

6

Small-scale

0.437

High

245966

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

1

High-throughput

0.437

High

245970

ERCC8
DNA excision repair protein ERCC-8

1

4

Small-scale

0.437

High

246058

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.437

High

246059

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.437

High

245937

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

246063

KLDC2
Kelch domain-containing protein 2

2

0

High-throughput

0.328

High

245984

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.323

High

246006

ARG39
Rho guanine nucleotide exchange factor 39

2

0

High-throughput

0.298

High

246065

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.282

High

64630

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.279

Low

245986

KR133
Keratin-associated protein 13-3

1

0

High-throughput

0.279

Low

245998

NEK10
Serine/threonine-protein kinase Nek10

1

0

High-throughput

0.279

Low

246000

LARP4
La-related protein 4

1

0

High-throughput

0.279

Low

246002

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.279

Low

246007

DB123
Beta-defensin 123

1

0

High-throughput

0.279

Low

246014

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.279

Low

246019

ESPB1
Epididymal sperm-binding protein 1

1

0

High-throughput

0.279

Low

246027

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

0

High-throughput

0.279

Low

246032

SPI2B
Spindlin-2B

1

0

High-throughput

0.279

Low

246039

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.279

Low

246045

RC3H2
Roquin-2

1

0

High-throughput

0.279

Low

246062

PKHA6
Pleckstrin homology domain-containing family A member 6

1

0

High-throughput

0.279

Low

165126

PLXB2
Plexin-B2

1

0

High-throughput

0.265

Low

245929

EOMES
Eomesodermin homolog

1

0

High-throughput

0.265

Low

245938

CMGA
Chromogranin-A

1

0

High-throughput

0.265

Low

245939

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

245940

HXD8
Homeobox protein Hox-D8

1

0

High-throughput

0.265

Low

245941

PTN
Pleiotrophin

1

0

High-throughput

0.265

Low

245968

HMGX3
HMG domain-containing protein 3

1

0

High-throughput

0.265

Low

245977

IF4A2
Eukaryotic initiation factor 4A-II

1

0

High-throughput

0.265

Low

245978

ZN235
Zinc finger protein 235

1

0

High-throughput

0.265

Low

245982

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.265

Low

245985

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.265

Low

245989

TTC38
Tetratricopeptide repeat protein 38

1

0

High-throughput

0.265

Low

245997

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.265

Low

246004

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.265

Low

246013

BRK1
Protein BRICK1

1

0

High-throughput

0.265

Low

246016

EXT2
Exostosin-2

1

0

High-throughput

0.265

Low

246020

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.265

Low

246023

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.265

Low

246024

IF140
Intraflagellar transport protein 140 homolog

1

0

High-throughput

0.265

Low

246028

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.265

Low

246044

RMI1
RecQ-mediated genome instability protein 1

1

0

High-throughput

0.265

Low

246068

SNX5
Sorting nexin-5

1

0

High-throughput

0.265

Low

245962

ACTS
Actin, alpha skeletal muscle

1

0

Small-scale

0.261

Low

153970

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.251

Low

245928

YETS4
YEATS domain-containing protein 4

1

0

Small-scale

0.251

Low

245988

GASP1
G-protein coupled receptor-associated sorting protein 1

1

0

High-throughput

0.251

Low

245990

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

245944

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

245946

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.249

Low

245947

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.249

Low

245981

SKI2
Superkiller complex protein 2

1

0

High-throughput

0.249

Low

246005

YAF2
YY1-associated factor 2

1

0

High-throughput

0.249

Low

246049

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

246066

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.249

Low

245956

DEF1
Neutrophil defensin 1

1

0

High-throughput

0.238

Low

246017

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.238

Low

246043

SYNG1
Synapse differentiation-inducing gene protein 1

1

0

High-throughput

0.238

Low

245948

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024