Protein: ZCHC3
Zinc finger CCHC domain-containing protein 3

Gene: ZCHC3, ZCCHC3
Organism: Homo sapiens
Interactions: 177
UniProt ID: Q9NUD5

Gene Ontology (top 5):
GO:0002218 - activation of innate immune response
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1334550

LN28A
Protein lin-28 homolog A

2

11

High-throughput

0.776

High

1345912

YBOX2
Y-box-binding protein 2

1

9

High-throughput

0.691

High

929687

RACK1
Small ribosomal subunit protein RACK1

3

6

High-throughput

0.667

High

1316904

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

3

8

High-throughput

0.667

High

1327217

PAIP1
Polyadenylate-binding protein-interacting protein 1

3

2

High-throughput

0.667

High

1019662

ILF2
Interleukin enhancer-binding factor 2

3

0

High-throughput

0.638

High

1201707

ZCH18
Zinc finger CCCH domain-containing protein 18

3

0

High-throughput

0.638

High

641953

U2AF2
Splicing factor U2AF 65 kDa subunit

2

4

High-throughput

0.628

High

1020336

ELAV2
ELAV-like protein 2

2

7

High-throughput

0.628

High

1222978

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

2

2

High-throughput

0.628

High

1168962

LN28B
Protein lin-28 homolog B

1

10

High-throughput

0.618

High

171848

WDR46
WD repeat-containing protein 46

2

4

High-throughput

0.611

High

453648

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

7

High-throughput

0.611

High

971370

H11
Histone H1.1

2

11

High-throughput

0.611

High

1085982

IF16
Gamma-interferon-inducible protein 16

2

2

High-throughput

0.611

High

1116575

LARP7
La-related protein 7

2

13

High-throughput

0.611

High

1268180

LAR4B
La-related protein 4B

2

4

High-throughput

0.611

High

1345898

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

1

High-throughput

0.611

High

269074

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.586

High

603749

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

3

High-throughput

0.584

High

1018081

GRSF1
G-rich sequence factor 1

2

7

High-throughput

0.584

High

1136314

RC3H1
Roquin-1

2

3

Small-scale

0.584

High

1152539

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

3

High-throughput

0.584

High

1241025

SERB1
SERPINE1 mRNA-binding protein 1

2

1

High-throughput

0.584

High

1335190

RC3H2
Roquin-2

2

4

Small-scale

0.584

High

718231

BMI1
Polycomb complex protein BMI-1

2

2

High-throughput

0.571

High

1317606

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

8

Small-scale

0.561

High

47878

RBM47
RNA-binding protein 47

1

7

High-throughput

0.536

High

71255

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

4

High-throughput

0.536

High

241374

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

4

High-throughput

0.536

High

273273

SURF6
Surfeit locus protein 6

1

2

High-throughput

0.536

High

281439

RL1D1
Ribosomal L1 domain-containing protein 1

1

4

High-throughput

0.536

High

401136

RLA0
Large ribosomal subunit protein uL10

1

6

High-throughput

0.536

High

432957

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

9

High-throughput

0.536

High

489302

H14
Histone H1.4

1

11

High-throughput

0.536

High

550982

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.536

High

559264

H15
Histone H1.5

1

11

High-throughput

0.536

High

559512

H13
Histone H1.3

1

11

High-throughput

0.536

High

559970

H12
Histone H1.2

1

11

High-throughput

0.536

High

578158

RL17
Large ribosomal subunit protein uL22

1

5

High-throughput

0.536

High

613593

SFPQ
Splicing factor, proline- and glutamine-rich

1

8

High-throughput

0.536

High

759853

RS19
Small ribosomal subunit protein eS19

1

5

High-throughput

0.536

High

781836

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.536

High

790587

RL35
Large ribosomal subunit protein uL29

1

3

High-throughput

0.536

High

807025

RS9
Small ribosomal subunit protein uS4

1

5

High-throughput

0.536

High

898508

RS3A
Small ribosomal subunit protein eS1

1

7

High-throughput

0.536

High

916906

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.536

High

922420

RL31
Large ribosomal subunit protein eL31

1

6

High-throughput

0.536

High

952146

SRSF3
Serine/arginine-rich splicing factor 3

1

15

High-throughput

0.536

High

992957

SRSF1
Serine/arginine-rich splicing factor 1

1

12

High-throughput

0.536

High

1028841

SRSF5
Serine/arginine-rich splicing factor 5

1

12

High-throughput

0.536

High

1029124

SRSF6
Serine/arginine-rich splicing factor 6

1

17

High-throughput

0.536

High

1040707

KRR1
KRR1 small subunit processome component homolog

1

3

High-throughput

0.536

High

1042641

CUL3
Cullin-3

1

4

High-throughput

0.536

High

1073871

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

9

High-throughput

0.536

High

1076122

OASL
2'-5'-oligoadenylate synthase-like protein

1

2

High-throughput

0.536

High

1084427

SRSF7
Serine/arginine-rich splicing factor 7

1

14

High-throughput

0.536

High

1101016

RN151
RING finger protein 151

1

2

High-throughput

0.536

High

1202139

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1291210

NEIL1
Endonuclease 8-like 1

1

1

High-throughput

0.536

High

1326267

REXO4
RNA exonuclease 4

1

2

High-throughput

0.536

High

1345900

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.536

High

1345902

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

1345903

HSPB8
Heat shock protein beta-8

1

1

High-throughput

0.536

High

1345906

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

1

High-throughput

0.536

High

1345908

ABT1
Activator of basal transcription 1

1

2

High-throughput

0.536

High

1345911

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

2

High-throughput

0.536

High

1345913

RBM19
Probable RNA-binding protein 19

1

9

High-throughput

0.536

High

181258

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

945361

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1345896

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1345897

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

1345905

ZN346
Zinc finger protein 346

1

0

High-throughput

0.513

High

1345914

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

1317746

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

3

High-throughput

0.500

High

180476

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.489

High

316176

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.489

High

470576

H2A1
Histone H2A type 1

1

4

High-throughput

0.489

High

1288637

PABP5
Polyadenylate-binding protein 5

1

6

High-throughput

0.489

High

1295852

ZN668
Zinc finger protein 668

1

2

High-throughput

0.489

High

1335778

CBX8
Chromobox protein homolog 8

1

1

High-throughput

0.489

High

134221

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

High-throughput

0.479

High

228842

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

233902

HBP1
HMG box-containing protein 1

1

1

High-throughput

0.479

High

298827

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

304364

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

High-throughput

0.479

High

321941

RIGI
Antiviral innate immune response receptor RIG-I

1

9

Small-scale

0.479

High

323200

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

348012

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

349681

RASH
GTPase HRas

1

3

Small-scale

0.479

High

442532

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

11

High-throughput

0.479

High

516714

PABP1
Polyadenylate-binding protein 1

1

6

High-throughput

0.479

High

668434

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

9

High-throughput

0.479

High

893173

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

898765

RL26
Large ribosomal subunit protein uL24

1

9

High-throughput

0.479

High

958248

RBM3
RNA-binding protein 3

1

8

Small-scale

0.479

High

1040431

TRA2A
Transformer-2 protein homolog alpha

1

6

High-throughput

0.479

High

1052782

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

3

Small-scale

0.479

High

1054614

RBM39
RNA-binding protein 39

1

6

High-throughput

0.479

High

1056758

PUM1
Pumilio homolog 1

1

3

High-throughput

0.479

High

1089573

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

9

High-throughput

0.479

High

1128548

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1153943

IFIX
Pyrin and HIN domain-containing protein 1

1

2

High-throughput

0.479

High

1171916

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1187811

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

2

High-throughput

0.479

High

1242141

LS14A
Protein LSM14 homolog A

1

2

High-throughput

0.479

High

1269726

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1272114

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.479

High

1272491

DAZL
Deleted in azoospermia-like

1

6

High-throughput

0.479

High

1294266

FUBP3
Far upstream element-binding protein 3

1

5

High-throughput

0.479

High

1307011

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1308707

PAIP2
Polyadenylate-binding protein-interacting protein 2

1

1

High-throughput

0.479

High

1310860

TRI56
E3 ubiquitin-protein ligase TRIM56

1

1

High-throughput

0.479

High

1318510

TRI31
E3 ubiquitin-protein ligase TRIM31

1

2

High-throughput

0.479

High

1326995

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

1

High-throughput

0.479

High

1335980

MOV10
Helicase MOV-10

1

1

High-throughput

0.479

High

1345895

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

3

High-throughput

0.479

High

1345899

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

5

High-throughput

0.479

High

1345901

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1345904

AGO2
Protein argonaute-2

1

3

High-throughput

0.479

High

1345915

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

6

High-throughput

0.479

High

821056

PRC2A
Protein PRRC2A

1

0

High-throughput

0.458

High

824433

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

1053996

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

1071706

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1168852

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1192390

YTHD3
YTH domain-containing family protein 3

1

0

High-throughput

0.458

High

1206074

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

1237489

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1293515

PRR11
Proline-rich protein 11

1

0

High-throughput

0.458

High

1294049

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1344494

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

70207

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

3

High-throughput

0.445

High

484043

CALM2
Calmodulin-2

1

2

High-throughput

0.445

High

484208

CALM3
Calmodulin-3

1

2

High-throughput

0.445

High

920899

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

5

High-throughput

0.445

High

1044186

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.445

High

1284321

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

3

High-throughput

0.445

High

101220

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

379922

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.437

High

472950

H2AB2
Histone H2A-Bbd type 2/3

1

3

High-throughput

0.437

High

553841

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

721569

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

850208

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.437

High

903545

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.437

High

909198

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1063641

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.437

High

1080394

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

1188926

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1260925

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.437

High

1288587

ZBT10
Zinc finger and BTB domain-containing protein 10

1

1

Small-scale

0.437

High

1334425

NANOG
Homeobox protein NANOG

1

1

High-throughput

0.437

High

1345907

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

1345909

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.437

High

1047283

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1345910

LORF1
LINE-1 retrotransposable element ORF1 protein

1

0

Small-scale

0.426

High

517493

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.417

High

69627

B0UZZ8
Chromosome 6 open reading frame 11

1

4

High-throughput

0.407

High

1153407

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.407

High

1241643

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

814667

CDX1
Homeobox protein CDX-1

2

0

High-throughput

0.328

High

883436

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.279

Low

1029197

NOGG
Noggin

1

0

High-throughput

0.279

Low

1245201

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.279

Low

1259616

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

1327706

SHRPN
Sharpin

1

0

High-throughput

0.279

Low

175239

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

652378

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

1053668

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1152443

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.249

Low

1255704

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.249

Low

1343671

ANLN
Anillin

1

0

High-throughput

0.249

Low

1124635

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.232

Low

1145949

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low

1255806

Q8TE30
RNA-directed DNA polymerase

1

0

Small-scale

0.232

Low

1298070

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.232

Low

1299760

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024