Protein: TR10B
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)

Gene: TR10B, TNFRSF10B
Organism: Homo sapiens
Interactions: 157
UniProt ID: O14763

Gene Ontology (top 5):
GO:0002357 - defense response to tumor cell
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0007166 - cell surface receptor signaling pathway
GO:0007250 - activation of NF-kappaB-inducing kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154326

TNF10
Tumor necrosis factor ligand superfamily member 10

19

20

Small-scale

0.985

High

154354

FADD
FAS-associated death domain protein

13

20

Small-scale

0.977

High

121420

TR10A
Tumor necrosis factor receptor superfamily member 10A

5

16

Small-scale

0.927

High

154317

TNR3
Tumor necrosis factor receptor superfamily member 3

3

16

High-throughput

0.861

High

154370

MICA
MHC class I polypeptide-related sequence A

3

1

High-throughput

0.861

High

154359

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

3

18

Small-scale

0.827

High

68218

HECA2
HEPACAM family member 2

3

6

High-throughput

0.770

High

154364

CASP8
Caspase-8

17

16

Small-scale

0.762

High

154283

CFLAR
CASP8 and FADD-like apoptosis regulator

5

16

Small-scale

0.702

High

154277

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

15

High-throughput

0.691

High

154369

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.691

High

154281

SCAM1
Secretory carrier-associated membrane protein 1

3

4

High-throughput

0.667

High

154297

FGFR1
Fibroblast growth factor receptor 1

3

19

High-throughput

0.667

High

154301

INGR1
Interferon gamma receptor 1

3

4

High-throughput

0.667

High

154367

VAMP3
Vesicle-associated membrane protein 3

3

4

High-throughput

0.667

High

154377

TM214
Transmembrane protein 214

3

3

High-throughput

0.667

High

154382

LAP4B
Lysosomal-associated transmembrane protein 4B

3

2

High-throughput

0.667

High

154386

S15A4
Solute carrier family 15 member 4

3

1

High-throughput

0.667

High

154409

NFIP1
NEDD4 family-interacting protein 1

3

3

High-throughput

0.667

High

154428

FLVC1
Heme transporter FLVCR1

3

2

High-throughput

0.667

High

154346

CD83
CD83 antigen

1

0

High-throughput

0.656

High

154352

TRAF2
TNF receptor-associated factor 2

3

20

Small-scale

0.640

High

154427

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

3

0

High-throughput

0.638

High

154294

FYN
Tyrosine-protein kinase Fyn

2

10

High-throughput

0.628

High

154299

IL1R1
Interleukin-1 receptor type 1

2

6

High-throughput

0.628

High

154321

EAA3
Excitatory amino acid transporter 3

2

3

High-throughput

0.628

High

154350

DDR1
Epithelial discoidin domain-containing receptor 1

2

17

High-throughput

0.628

High

154393

S20A1
Sodium-dependent phosphate transporter 1

2

1

High-throughput

0.628

High

154400

ARRD3
Arrestin domain-containing protein 3

2

3

High-throughput

0.628

High

154322

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.618

High

154365

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

10

Small-scale

0.618

High

154349

CKAP4
Cytoskeleton-associated protein 4

2

5

High-throughput

0.611

High

154356

STX3
Syntaxin-3

2

4

High-throughput

0.611

High

154284

TSN3
Tetraspanin-3

3

2

High-throughput

0.609

High

154330

MFAP3
Microfibril-associated glycoprotein 3

3

2

High-throughput

0.609

High

154387

RN149
E3 ubiquitin-protein ligase RNF149

3

3

High-throughput

0.609

High

154304

MUC1
Mucin-1

2

3

High-throughput

0.606

High

154351

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

1

High-throughput

0.606

High

154278

TR13B
Tumor necrosis factor receptor superfamily member 13B

2

0

High-throughput

0.602

High

154341

ASIC1
Acid-sensing ion channel 1

2

0

High-throughput

0.602

High

154333

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.595

High

154401

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.586

High

154309

CBL
E3 ubiquitin-protein ligase CBL

2

10

Small-scale

0.584

High

154338

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

Small-scale

0.584

High

154362

CUL3
Cullin-3

2

9

Small-scale

0.584

High

154425

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.578

High

154307

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

17

Small-scale

0.575

High

154311

TNR6
Tumor necrosis factor receptor superfamily member 6

1

16

Small-scale

0.575

High

154325

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

20

Small-scale

0.575

High

154404

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

3

High-throughput

0.574

High

154426

RNF11
RING finger protein 11

2

4

High-throughput

0.574

High

154335

RHOA
Transforming protein RhoA

2

20

Small-scale

0.571

High

154397

CASPA
Caspase-10

2

16

Small-scale

0.571

High

154368

CEGT
Ceramide glucosyltransferase

2

2

High-throughput

0.558

High

154406

ZDH15
Palmitoyltransferase ZDHHC15

2

3

High-throughput

0.553

High

154344

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

9

Small-scale

0.553

High

154279

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.536

High

154287

VAMP5
Vesicle-associated membrane protein 5

1

4

High-throughput

0.536

High

154306

INAR1
Interferon alpha/beta receptor 1

1

8

High-throughput

0.536

High

154314

V2R
Vasopressin V2 receptor

1

3

High-throughput

0.536

High

154315

RYK
Tyrosine-protein kinase RYK

1

17

High-throughput

0.536

High

154318

TGFR2
TGF-beta receptor type-2

1

10

High-throughput

0.536

High

154319

OPRX
Nociceptin receptor

1

3

High-throughput

0.536

High

154324

GPR3
G-protein coupled receptor 3

1

6

High-throughput

0.536

High

154327

GPM6A
Neuronal membrane glycoprotein M6-a

1

2

High-throughput

0.536

High

154334

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.536

High

154342

KC1G2
Casein kinase I isoform gamma-2

1

10

High-throughput

0.536

High

154348

ACVR1
Activin receptor type-1

1

10

High-throughput

0.536

High

154357

SLAF1
Signaling lymphocytic activation molecule

1

11

High-throughput

0.536

High

154363

AVR2B
Activin receptor type-2B

1

10

High-throughput

0.536

High

154378

I20RB
Interleukin-20 receptor subunit beta

1

4

High-throughput

0.536

High

154388

PLPR1
Phospholipid phosphatase-related protein type 1

1

1

High-throughput

0.536

High

154389

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

6

High-throughput

0.536

High

154391

PKR1
Prokineticin receptor 1

1

2

High-throughput

0.536

High

154396

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.536

High

154398

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

10

High-throughput

0.536

High

154399

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

4

High-throughput

0.536

High

154408

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

7

High-throughput

0.536

High

154410

SYT11
Synaptotagmin-11

1

1

High-throughput

0.536

High

154412

PCDC1
Protocadherin alpha-C1

1

1

High-throughput

0.536

High

154417

GPR35
G-protein coupled receptor 35

1

4

High-throughput

0.536

High

154420

GPC5D
G-protein coupled receptor family C group 5 member D

1

4

High-throughput

0.536

High

154421

GPC5B
G-protein coupled receptor family C group 5 member B

1

4

High-throughput

0.536

High

154422

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

6

High-throughput

0.536

High

154424

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

18

High-throughput

0.536

High

154374

MARH8
E3 ubiquitin-protein ligase MARCHF8

2

6

Small-scale

0.533

High

154292

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.515

High

154329

GDIR1
Rho GDP-dissociation inhibitor 1

1

2

Small-scale

0.514

High

154288

CSPG5
Chondroitin sulfate proteoglycan 5

1

0

High-throughput

0.513

High

154375

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.513

High

154390

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

154411

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

154419

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.513

High

154429

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

154310

PRPH2
Peripherin-2

1

2

High-throughput

0.489

High

154372

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

5

High-throughput

0.489

High

154290

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

154291

RASK
GTPase KRas

1

5

High-throughput

0.479

High

154293

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

154295

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

154298

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

154300

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

154305

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

154308

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

8

Small-scale

0.479

High

154320

BCL6
B-cell lymphoma 6 protein

1

7

Small-scale

0.479

High

154328

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

154332

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

154336

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

154343

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

154347

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

154355

CBLB
E3 ubiquitin-protein ligase CBL-B

1

9

Small-scale

0.479

High

154360

IRF5
Interferon regulatory factor 5

1

1

Small-scale

0.479

High

154361

CUL1
Cullin-1

1

9

Small-scale

0.479

High

154366

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

154380

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

154403

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

Small-scale

0.479

High

154405

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

154407

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

1

2

Small-scale

0.479

High

154413

DNJC5
DnaJ homolog subfamily C member 5

1

6

High-throughput

0.479

High

154414

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

154416

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

154296

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

154337

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

154358

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

154384

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.458

High

154395

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.458

High

154402

RN183
E3 ubiquitin-protein ligase RNF183

1

0

Small-scale

0.458

High

154289

TSN12
Tetraspanin-12

1

2

Small-scale

0.445

High

154302

EZRI
Ezrin

1

9

Small-scale

0.445

High

154312

MOES
Moesin

1

9

Small-scale

0.445

High

154323

MK08
Mitogen-activated protein kinase 8

1

7

Small-scale

0.445

High

154331

BID
BH3-interacting domain death agonist

1

2

Small-scale

0.445

High

154353

PAK1
Serine/threonine-protein kinase PAK 1

1

2

Small-scale

0.445

High

154371

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

3

Small-scale

0.439

High

154280

TRI66
Tripartite motif-containing protein 66

1

2

High-throughput

0.437

High

154282

BET1
BET1 homolog

1

1

High-throughput

0.437

High

154285

PRAF2
PRA1 family protein 2

1

2

High-throughput

0.437

High

154286

PRDM1
PR domain zinc finger protein 1

1

7

Small-scale

0.437

High

154316

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

154339

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.437

High

154340

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

154345

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.437

High

154379

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

154381

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

6

High-throughput

0.437

High

154385

STX12
Syntaxin-12

1

3

High-throughput

0.437

High

154392

RN128
E3 ubiquitin-protein ligase RNF128

1

3

High-throughput

0.437

High

154423

DNJ5B
DnaJ homolog subfamily C member 5B

1

7

High-throughput

0.437

High

154376

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

6

High-throughput

0.407

High

154415

TM231
Transmembrane protein 231

3

0

High-throughput

0.347

High

154418

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.347

High

49114

TM223
Transmembrane protein 223

2

0

High-throughput

0.328

High

147988

C56D2
Transmembrane reductase CYB561D2

1

0

High-throughput

0.279

Low

154394

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

154373

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

154303

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

154313

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

154383

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024